Circulation
Articles in this Issue
Abstract TH984: Adverse gestational outcomes elevate risk of cardiac and vascular dysfunction in pre-menopausal women
Introduction: Pregnancy is considered the ultimate stress test on the body, as it may reveal or accelerate underlying cardiovascular risks in women. Existing studies have focused o...
Abstract TH819: Association between adherence to the Dietary Approaches to Stop Hypertension and cognitive performance in individuals with and without diabetes: data from a large population-based study from Germany
Background: Diabetes is a known risk factor for impaired cognitive function. Higher adherence to healthy dietary patterns, such as the Dietary Approaches to Stop Hypertension (DASH...
Abstract MPTH74: Metabolomic Responses to Diets Varying in Carbohydrate and Glycemic Index Are Linked to Improved Glucose Metabolism and Insulin Sensitivity: OmniCarb and POUNDS Lost
Background: The effects of reducing dietary carbohydrate intake and glycemic index (GI) levels on temporal changes in blood metabolomic profiles and their impact on improving gluco...
Abstract TU238: Cumulative cardiovascular health over two decades and subclinical target organ damage in the Framingham Heart Study
Introduction: Single measures of cardiovascular health (CVH) have been related to risk of numerous outcomes beyond cardiovascular diseases (CVD). However, data are sparse regarding...
Abstract 12: Phthalate Exposure as a Second Hit for APOL1-Associated Chronic Kidney Disease Progression
Introduction: Carrying two risk alleles in the apolipoprotein L1 ( APOL1 ) gene is a well-established risk factor for chronic kidney disease...
Abstract WE523: Prevalence of Clinical Obesity in Brazilians: Cross-Sectional Results from the Health Survey of São Paulo with a Focus on Nutrition
Introduction: Obesity has traditionally been defined using BMI thresholds. While BMI is useful for population screening, it sometimes misclassifies individuals. Considering this,...
Abstract TH974: Left Ventricular Mass Index Changes across 20 Years of Follow-up Among Pre-Menopausal Women: The National Growth and Health Study
Introduction: Left ventricular mass index (LVMI) is a known risk factor for cardiovascular (CV) disease. However, little is known about changes in LVMI across the lifespan, especia...
Abstract WE454: Trends in Global Cardiovascular Disease Mortality from 1990 - 2022
Introduction: Heart disease remains the leading cause of mortality worldwide. We examined global heart disease mortality trends over the past three decades to assess progress made...
Abstract TH852: Real-Time Mitral Valve Segmentation on 3-D Transesophageal Echocardiography with Quality Assurance for Intraoperative Decision Support
Background: Intraoperative decision making for mitral valve repair relies on rapid, reliable assessment of leaflet anatomy from three-dimensional transesophageal echocardiography (...
Abstract 06: Comparative Effectiveness of Semaglutide and Tirzepatide on Cardiovascular Outcomes among Patients with Obesity and Established Cardiovascular Disease
Introduction: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and the dual glucose-dependent insulinotropic polypeptide and GLP-1 receptor agonist tirzepatide have shown card...
Abstract TU159: Association Between Life’s Essential 8 and Hypertension Control: Evidence From NHANES 2021–2023
Background: Hypertension remains a leading modifiable risk factor for cardiovascular disease, yet many U.S. adults fail to achieve adequate blood pressure (BP) control. The America...
Abstract TH926: Association between Frailty and Peripheral Artery Disease among Older Adults: the Atherosclerosis Risk in Communities (ARIC) Study
Introduction: Peripheral artery disease (PAD) is a subtype of atherosclerotic cardiovascular disease (CVD) involving the occlusion of arteries in the lower extremities. Frailty has...
Abstract TU114: The Neighborhood Built Environment and Cardiometabolic Risk Factors in The Bogalusa Heart Study
Introduction: Rural residents are at a higher risk for early cardiovascular morbidity and mortality in midlife compared to urban populations. The neighborhood built environment (NB...
Abstract WE555: Trends in Mortality Due to Use of Tobacco in Coronary Artery Disease Patients Among Younger and Older Adults from 1999-2023 in the USA
Background: Tobacco use remains a major modifiable risk factor for coronary artery disease (CAD), amplifying cardiovascular risk when combined with other comorbidities. While cigar...
Abstract TU276: Association Between Health Care Access and Cardiovascular Health Risk Among Reproductive-Aged Women in the SAFE HEART Study
Background: Limited access to healthcare can influence cardiovascular health behaviors and outcomes. Few studies have examined this relationship, especially among women of reproduc...
Abstract WE406: Unhealthy Alcohol Use and Sudden Death Among Working Age Adults
Background: Unhealthy alcohol use may lead to arrythmias and cardiomyopathy, but its impact on sudden death is not well known. To investigate the association of unhealthy alcohol u...
Abstract WE497: The Geography of a Heartbeat: Mapping the Social Drivers of Cardiovascular Mortality
Cardiovascular disease (CVD) is the number one cause of death in the US. Although most states have made significant headway in reducing their CVD death rates, some still lag behind. West Virginia has...
Abstract WE551: A Population-Based Study of Modifiable Social and Behavioral Factors and Heart Aging
Introduction: The novel PREVENT risk age construct (age of a hypothetical person with the same absolute risk but optimal risk factors) may better communicate risk than absolute CVD...
Abstract MPTU06: Prediction of cardiovascular diseases using statistical and machine learning approaches: The Strong Heart Study
Background: Machine learning (ML) models are highly non-linear functions that are known to have good prediction ability in the classification paradigms, from binary to multi-class...
Abstract TU127: Maternal gestational diabetes and childhood hypertension risk
Background: Several studies have investigated the association between maternal gestational diabetes mellitus (GDM) and the risk of elevated blood pressure in offspring, but finding...
Abstract WE450: Association between Multiple Urinary Metals and Metal Mixtures and Ectopic Adiposity in Caribbean Men: The Tobago Health Study
Background: Previous studies reported an association between several urinary metals/metalloids (e.g. arsenic, cadmium, lead) and obesity. However, the majority of studies assessed...
Abstract TU212: Prediction of Early-Onset Preeclampsia Using Deep Learning: A Systematic Review of Clinical and Imaging Models
Background: Early-onset preeclampsia is a leading cause of maternal and perinatal morbidity and mortality. Deep learning (DL) offers a promising approach for early prediction, but...
Abstract MPTH66: No Significant Six-Month Changes in Lifestyle Behaviors Among Adults with Elevated BP or Stage 1 Hypertension in the LINKED-BP Program
Background: Lifestyle modification is central to hypertension prevention and control. Despite its recognized importance, few community-based clinical trials have evaluated short-te...
Abstract TH802: Adverse Events Associated with Immune Checkpoint Inhibitors in a Real-World Hispanic Cohort: Analysis of Cardiovascular Outcomes
Background: Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, yet data on cardiovascular and thrombotic safety in Hispanic populations are limited. Evidence from...
Abstract MPTU21: Proactive Outreach May Mitigate Disengagement in Electronic Healthy Eating Interventions: A Qualitative Study
Background: The US population eats less than recommended amounts of fruit and vegetables (F&V). We conducted a randomized clinical trial to test whether a $160 monthly F&V...