Circulation
Articles in this Issue
Abstract TH901: Geographic Disparities in Transcatheter Aortic Valve Replacement (TAVR) Outcomes at Shasta Regional Medical Center: Assessing the Impact of Rural Residence, Comorbidities, and Access to Care.
Intro: Transcatheter Aortic Valve Replacement (TAVR) is the standard of care for patients with symptomatic aortic stenosis and high surgery risk. However, access to TAVR varies and...
Abstract TU269: Cross-Sectional Associations of Sleep with Atrial Cardiopathy in Adults with Overweight or Obesity
Background: Sleep disturbances are prevalent among individuals with excess adiposity and may contribute to atrial abnormalities. However, the relationship between sleep and atrial...
Abstract TH833: Patient characteristics associated with 90-day referral to a home-based cardiac rehabilitation program in Kaiser Permanente Southern California
Background: Cardiac rehabilitation (CR) is a guideline-recommended exercise and lifestyle management program to support individuals recovering from a cardiovascular event or proced...
Abstract TU120: MS#1072 Association of chronic kidney disease with COVID-19 disease severity in the Hispanics/Latinos: the HCHS/SOL study
Introduction: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in significant morbidity and mortality. Disp...
Abstract 14: Impact of High Intensity Interval Training versus Continuous Moderate Intensity Exercise on Cardiorespiratory Fitness for People with HIV: Results from the HEALTH Multicenter Randomized Clinical Trial
Objectives: HIV is associated with reduced cardiorespiratory fitness (CRF), a strong predictor of future cardiovascular events and mortality. Supervised exercise training programs...
Abstract MPWE44: A multi-ancestry blood metabolites atlas of incident stroke in ~39,000 adults
Background: A comprehensive blood metabolome fingerprint of incident stroke and the temporal variation of metabolite levels across pre-diagnostic trajectories remain poorly defined...
Abstract 05: Evaluating the Implications of PREVENT Risk Estimates for Non-Cardiovascular Outcomes: The Atherosclerosis Risk in Communities (ARIC) Study
Introduction: In response to the growing burden of poor cardiovascular-kidney-metabolic (CKM) health, the PREVENT equations were developed to incorporate emerging risk factors and...
Abstract TH849: Machine Learning-Based Magnetic Respiratory Sensing Technology and Hypergraph Network Modeling of Respiratory and Cardiovascular Comorbidity
Background: Cardiovascular diseases (CVDs) are a leading cause of death globally, and coexisting respiratory diseases (RDs) amplify clinical risk and care complexity. A noninvasive...
Abstract TH898: Cardiovascular Health by Life's Essential 8 in Southeast Asian Adults in the United States
Background: Cardiovascular disease burden and risk factors have been shown to differ across Asian American subgroups, with notably high prevalence of elevated cholesterol and diabe...
Abstract MPWE48: Metabolomics-Based Reclassification of Ultra-Processed Foods and Risk of Cardiometabolic Outcomes
Introduction: Ultra-processed foods (UPFs) are commonly treated as a single category, yet they encompass nutritionally heterogeneous products with potentially differential health e...
Abstract 17: Aberrant Heart Rate Variability in Late Midlife Associates with Future Cognitive Decline: Findings From the 1946 British Birth Cohort
Introduction: Autonomic nervous system dysfunction has been demonstrated in Alzheimer’s disease. Impaired autonomic function represented by aberrant heart rate variability (HRV) ma...
Abstract TU230: Cholesterol Management Gaps Before a Recurrent Coronary Event: Insights From the Get With The Guidelines – Coronary Artery Disease Registry
Introduction: Guidelines recommend that patients with coronary artery disease (CAD) lower their low-density lipoprotein cholesterol (LDL-C) using maximally tolerated statin therapy...
Abstract TH952: Self-reported stress overload experience, autonomic tone and acute mental stress cardiovascular reactivity: The African-PREDICT study
Background: Stress, stress perceptions, appraisals and perceived individual ability to manage stress significantly impact cardiovascular health in humans, yet this relationship is...
Abstract WE496: Variation in Risk Factor Control in Patients with Atrial Fibrillation by Race and Ethnicity: A Nationwide Study
Introduction: Atrial fibrillation (AF) is a common arrhythmia associated with stroke, death, and complications that are more prevalent among AF patients from minoritized groups. Th...
Abstract WE416: A Novel Poly-Metabolite Score of Soy Product Intake is Prospectively Associated with Cognitive Function
Introduction: Soy intake improves dementia risk factors in clinical trials. However, population studies reported inconsistent associations with cognitive outcomes, likely due to se...
Abstract MPWE36: Proteomics Reveals Altered Muscle Structure and Organization Pathways in Older Adults with Peripheral Neuropathy
Objectives: Peripheral neuropathy (PN) of the lower extremities is highly prevalent among older adults, even in the absence of diabetes, and has been linked to substantial morbidit...
Abstract TU192: Large-scale proteomic analysis of valvular calcification: The Atherosclerosis Risk in Communities (ARIC) Study
Background: Valvular heart disease shares risk factors with atherosclerosis, but its pathophysiology is not fully understood. We aimed to conduct a large-scale proteomic analysis f...
Abstract TU189: ABO Blood Type Modifies the Association Between Fiber Intake and Incident Cardiovascular Disease: The Role of Gut Microbiota and Circulating Metabolites
Introduction: ABO blood type is related to cardiovascular disease (CVD) and influence gut microbiota (GMB). ABO antigen glycans in the gut may influence GMB composition, with effec...
Abstract WE577: Associations of Occupational and Social Factors with Incident Kidney Stones in the Pro-Saude Study
Background: While occupational factors and social determinants of health (SDOH) are associated with kidney stone disease (KSD) risk in US cohorts, their role in other populations r...
Abstract TH884: Pulse Pressure as a Mediator of the Association Between Cognition and Bone Health in Older Women: Findings from the Study of Muscle, Mobility and Aging- Bone Ancillary Study (SOMMA Bone)
Background: Stiffening arteries, a risk factor of cognitive impairment, leads to increased pulse pressure (PP, difference between systolic and diastolic blood pressure). PP directl...
Abstract WE538: Sex Differences in Actigraphy-Measured Physical Activity Among Young Survivors of Acute Myocardial Infarction
Introduction: Light and moderate-to-vigorous physical activity (LPA and MVPA) are critical for secondary prevention in individuals with recent myocardial infarction (MI). Examining...
Abstract TU188: Association of the IgG and Plasma Glycomes with Cardiometabolic Risk Factors
Background: The immunoglobulin G (IgG) and plasma N-glycomes represent biomarkers of cardiovascular disease. However, few studies have examined relationships between glycomic profi...
Abstract TU129: Stress, Sleep, and the Heart: Identifying Early Biomarkers of Cardiovascular Risk in Puerto Rican Children
Background: Psychological stress during childhood can disrupt vascular homeostasis and increase long-term cardiovascular disease (CVD) risk. Endothelin-1 (ET-1), a potent vasoconst...
Abstract WE511: Reduced Blood Pressure and Improved Survival in Patients with Normal Blood Pressure to Severe Hypertension Treated with the Very Low Sodium Rice Diet
Introduction: High sodium intake increases risks of hypertension (HTN) and mortality, but the impact of very low sodium intake is uncertain. No studies have examined dietary sodium...
Abstract MPTH63: Effects Of Exercise Training On Predicted ASCVD Risk: Meta-Analysis Across Eight Exercise Training Studies
Background: Atherosclerotic cardiovascular disease (ASCVD) risk scores are commonly used to inform therapeutic strategies in the clinical setting. Although previous studies have sh...