Circulation
Articles in this Issue
Abstract TH891: Association of Cardiovascular and Social Risk Factors with Cognitive Function in Low Income Hypertension Patients with Low Cognitive Reserve
Introduction: Increasing evidence has identified modifiable risk factors for Alzheimer’s disease and related dementias (ADRD). Yet most studies include individuals with few cardiov...
Abstract TH876: Twenty-four-month Changes in Lipid Optimization among Urban and Rural Veterans: VALOR-QI program
Background: Optimal lipid management is critical for reducing cardiovascular events among those with atherosclerotic cardiovascular disease (ASCVD). When implementing LDL-C lowerin...
Abstract TU256: Trends and Disparities in Mortality from Pulmonary Embolism by Place of Death in the United States, 1999–2023
Background: Pulmonary embolism (PE) is a life-threatening cardiovascular condition with significant mortality. Despite advances in care, limited data exist on place of death (POD)...
Abstract WE570: Heat and cold waves are associated with increased stroke mortality in Brazil
Stroke is the second leading cause of death worldwide and a major public health concern in Brazil. Extreme heat is well recognized as a risk factor for ischemic stroke, but evidence on cold spells, ev...
Abstract WE460: Impact of Socioeconomic Status on Outcomes of a Digital Cardiovascular Self-Management Program
Background: Digital health programs can expand access to preventive care and potentially reduce inequities driven by social determinants of health. However, individuals with fewer...
Abstract WE452: Association of Diabetes with Cardiac Structure and Function Among African Caribbeans in Tobago: A Population Based Cohort Study
Diabetes Mellitus (DM) is closely associated cardiovascular events and adversely effects the cardiac structure and function. Although persons from African ancestry are at high risk of diabetes-related...
Abstract TH841: Advancing Life’s Essential 8: Machine Learning Reveals Actionable Predictors of Cardiovascular Mortality in NHANES 1999–2018
Introduction: In 2022, the American Heart Association introduced the Life's Essential 8 (LE8) enhanced metric of cardiovascular health (CVH), a strong predictor of all-cause and ca...
Abstract MPTU12: Impact of the DASH4D Diet on Post-prandial Glucose Patterns assessed by Continuous Glucose Monitoring in Adults with Type 2 Diabetes
Introduction: In a recent randomized trial, we showed that a DASH-style diet optimized for adults with type 2 diabetes (DASH4D) reduced mean glucose assessed by continuous glucose...
Abstract WE458: Effects of a Food-is-Medicine Intervention on Blood Pressure Among Black and Hispanic Adults with Hypertension in Healthy Food Priority Areas: The THRIVE Pilot Trial
Background: Nearly half of all U.S. adults live with hypertension, the most significant modifiable contributor to cardiovascular morbidity and mortality. Food is Medicine (FIM) int...
Abstract TU130: Food Insecurity and Pediatric Heart Health in US
Background: Food insecurity is a significant public health concern that may adversely affect children’s physical and emotional well-being, including cardiovascular health. Limited...
Abstract WE422: Prognostic Value of Cardiovascular-Kidney-Metabolic Syndrome Stage 3 Components: Dallas Heart Study
Background: The Cardiovascular-Kidney Metabolic (CKM) Syndrome Stages are associated with heightened risk of cardiovascular diseases (CVD). However, the individual and additive imp...
Abstract 24: Prospective Associations of PFAS with Cardiovascular Disease in Prediabetes: Diabetes Prevention Program
Background: Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants linked to cardiometabolic dysfunction, yet their prospective association with cardi...
Abstract WE481: Disrupted Circadian Rest-Activity Rhythms and Incident Heart Failure in the Aging Population: The Atherosclerosis Risk in Communities Study
Introduction: Circadian rhythm disruption is prevalent in older adults and has been linked to autonomic dysfunction, chronic inflammation, and metabolic dysregulation, which are ke...
Abstract WE514: Changes in epigenomics and metabolomics biomarkers after a lifestyle intervention with diet and physical activity for weight loss in high cardiovascular risk individuals
Background and aims: Obesity is recognized as an important cardiovascular risk factor. Consequently, weight loss is regarded as a protective factor. Nevertheless, the effects of we...
Abstract TH816: Carbohydrate Quality, Pathway-specific Polygenic Risk Scores, and Risk of Type 2 Diabetes among US Men and Women
Introduction: Carbohydrate quality is associated with type 2 diabetes (T2D) risk, but whether intakes of specific carbohydrates interact with genetic susceptibility remains unclear...
Abstract WE572: Intravascular ultrasound and hemodynamics in stenotic lesions of arteriovenous fistulas or grafts in patients on hemodialysis
Background: Chronic kidney disease (CKD) is a major public health crisis. In the US, one out of seven people has CKD. Of these, over 815,000 people have end-stage kidney disease (E...
Abstract WE530: Latinos that Engage in High Occupational Physical Activity are Less Likely to Engage in High Sedentary Activity
Introduction: Foreign-born Latinos engage in higher levels of occupational physical activity (OPA), yet lower levels of leisure-time physical activity, compared with US-born Latino...
Abstract MPWE45: Proteomic-Based Biological Aging Clocks Are Associated with Cognitive Aging: The Atherosclerosis Risk in Community Study
Background: Proteomic aging clocks (PACs) reflect multifactorial biological aging and have shown strong associations with dementia risk. However, it remains unclear whether PACs ca...
Abstract TU186: Plasma Metabolomics and Incident Heart Failure in Patients with Gout
Background: Individuals with gout have an elevated risk of developing heart failure (HF) compared to the general population. Larger HDL particle size associates with a higher HF ri...
Abstract TH956: Grim Age Acceleration Does Not Improve Risk Prediction of the PREVENT (Predicting Risk of Cardiovascular Disease Events) Base Equation
Introduction: The PREVENT (Predicting Risk of Cardiovascular Disease Events) equations estimate 10-year absolute risks for atherosclerotic CVD (ASCVD), heart failure (HF), and CVD...
Abstract TU162: Association Between Perceived Risk of Hypertension and Healthcare Utilization among Black Adults with Elevated Blood Pressure or Untreated Stage 1 Hypertension: Findings from the RESTORE Network
Introduction: Perceived risk of hypertension may influence health behaviors, but data are limited among Black adults, a population with a high prevalence of hypertension and low pr...
Abstract 67: Objectively Measured vs. Self-Reported Physical Activity and Coronary Artery Calcification: The Atherosclerosis Risk in Communities Study
Introduction: Coronary artery calcification (CAC) is a marker of subclinical atherosclerosis with important implications for cardiovascular risk assessment. Despite established car...
Abstract TH854: Digital Twins Powered by Generative Artificial Intelligence Support Long-Term Evaluation of Obesity and Cardiometabolic Outcomes
Introduction: Obesity and cardiometabolic diseases are leading contributors to global morbidity and mortality. Their interdependent progression is not well captured by existing mod...
Abstract TU227: Annual Change in High-Sensitivity Cardiac Troponin T and Risk of Cardiovascular Disease and Mortality: The Atherosclerosis Risk in Communities (ARIC) Study
Background: Measurable concentrations of high-sensitivity cardiac troponins (hs-cTn; hs-cTnT and hs-cTnI) reflect subclinical myocardial damage, define stage B heart failure (HF) w...
Abstract TH863: Assessing Differences in Hypertension Prevalence and Incidence by Sexual Orientation: Analysis using Electronic Health Records from an Illinois Health System
Background: The weathering hypothesis proposes that sexual minorities would have earlier onset of chronic disease like hypertension (HTN) due to chronic stress and discrimination....