Circulation
Articles in this Issue
Abstract TU145: Associations between per- and polyfluoroalkyl substance (PFAS) levels during early pregnancy and circulating cardiovascular proteins in women at 3 years postpartum: results from Project Viva
Introduction: PFAS are synthetic chemicals that persist in the environment and accumulate in humans. Higher PFAS exposure during pregnancy has been associated with poorer long-term...
Abstract TH947: Associations of Breakfast Skipping with Mental Health Status and Overweight, Obesity among African American College Students in the Southern US
Background: Breakfast skipping is common among college students and has been linked to adverse weight and psychological outcomes. African American adolescents and young adults expe...
Abstract TH981: Associations of Diet during Pregnancy with Cardiovascular Health (Life’s Essential 8) among Women in Midlife
Background: Cardiovascular health (CVH) often worsens among midlife women. Diet during pregnancy, a similarly sensitive period due to physiological and weight changes, may influenc...
Abstract WE408: Association of Acculturation with Ventricular Arrhythmias: Preliminary Findings from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Introduction: Some studies suggest that Hispanic/Latino immigrants in the U.S. have a lower risk of sudden cardiac death compared to non-Hispanic Whites and Blacks. However, it rem...
Abstract TU226: SALAM: Study of Arab-American Longitudinal Assessment of Morbidity Cardiometabolic Burden Across Age and Sex in a U.S. Health System
Background: Middle Eastern and North African (MENA) populations remain largely invisible in U.S. cardiovascular research due to the absence of ethnicity identifiers in clinical reg...
Abstract TH894: Blood Pressure at Intensive and Conservative Thresholds has Sex/Gender-Specific Associations With Cognition Function and Decline: a Quantile Regression Analysis in the Health and Retirement Study
Introduction: Sex/gender and age variability in the impact of elevated blood pressure (BP) on older adult cognitive function remains understudied across the continuum of cognition....
Abstract TU214: Profiles of Healthy Behaviors in Early Pregnancy are Associated with Maternal Allostatic Load in Pregnancy and 2-7 Years Following Delivery: The nuMoM2b-HHS1 Cohort
Background: Modifiable health behaviors are key components of cardiovascular health in pregnancy and the years after delivery, but the mechanisms by which early pregnancy behaviors...
Abstract TH933: Age-Related Differences in Uptake of Guideline-Directed Therapy for HFpEF During Hospitalization
Background: Guideline-directed medical therapy (GDMT) is a cornerstone of heart failure (HF) management. However, older adults often receive suboptimal treatment due to comorbiditi...
Abstract TH922: Dietary Conjugated Linoleic Acid Shapes the Host Plasma Metabolome and Gut Microbiome and Is Associated with Coronary Heart Disease in U.S. Individuals
Introduction: Conjugated linoleic acid (CLA), a ruminant-derived fatty acid abundant in dairy and red meat, has been consumed as a dietary supplement for its purported health benef...
Abstract WE457: Comparative Analysis of Hypertension Management Plans Generated by Large Language Models
Background: The use of large language models (LLMs) in clinical practice, medical education, and by patients is increasing rapidly. It is essential to ensure that information provi...
Abstract MPWE26: Breastfeeding and Early Childhood Cardiovascular Health in the ECHO Program
Background: Breastfeeding is linked with single indicators of maternal and child cardiovascular health (CVH), but its association with comprehensive childhood CVH as defined by AHA...
Abstract TH800: Shared Clinical and Genetic Determinants of Cardiometabolic Disease and Lung Cancer
Introduction: Cardiometabolic disease (CMD) may influence lung cancer risk through shared biological pathways and treatment effects. We examined clinical and genetic factors underl...
Abstract MPWE29: Maternal Cardiovascular Disease Events Within Four Years of Delivery Following Pregnancy Complicated by COVID-19 Infection in 2020-2022.
Introduction: COVID-19 has been associated with increased risk during pregnancy and increased long-term cardiovascular disease (CVD) risk; however, few studies have examined CVD ri...
Abstract WE546: Sex-Specific Lipidomic Signatures Associated With Obstructive Sleep Apnea Severity
Background: Obstructive sleep apnea (OSA) is a prevalent cardiometabolic disorder with known sex differences in presentation and diagnosis. The apnea–hypopnea index (AHI) often und...
Abstract WE541: Early Detection of Subclinical Myocardial Dysfunction in Diabetes Using Leak-Safe Machine Learning on Routine Clinical Data
Background: Diabetic patients may develop subclinical myocardial dysfunction despite preserved ejection fraction (EF≥50%) and normal Doppler indices. Speckle-tracking echocardiogra...
Abstract TH878: Explainable OCT-Based Atherosclerotic Plaque Segmentation Using Convolutional Neural Networks and Large Language Models
Objective: To develop and evaluate an explainable framework for automated segmentation of atherosclerotic plaque morphological features in optical coherence tomography (OCT) images...
Abstract MPTU18: Single Family Zoning and Optimal Cardiovascular Health Measured using the American Heart Association’s Life’s Essential 8 in the Multi-Ethnic Study of Atherosclerosis
Background: Single-family zoning (SFZ) is an urban planning regulation that prevents neighborhoods zoned for single-family homes from developing multifamily housing units, which ar...
Abstract TU221: The Role of Home Visiting Programs in Addressing Postpartum Cardiovascular Care Gaps: Evidence from a Large U.S. Community-Based Sample
Background: Maternal mortality in the United States has doubled over the last two decades, largely from cardiovascular disease, with over half of deaths occurring postpartum. Despi...
Abstract MPTU08: Semaglutide versus liraglutide and incidence of diabetes and cardiovascular disease: a target trial emulation using real-world data
Background: The glucagon-like peptide-1 receptor agonists (GLP-1 RAs) semaglutide (2.4 mg) and liraglutide (3.0 mg) are approved for chronic weight management. Both drugs also have...
Abstract TU141: Smoking-Related Proteins and Incident Chronic Obstructive Pulmonary Disease Hospitalizations: The Atherosclerosis Risk in Communities (ARIC) Study
Background: Cross-sectional studies have identified associations between smoking and various plasma proteins. Some studies have examined the association of these cross-sectional sm...
Abstract WE490: Neighborhood Socioeconomic Conditions Classify Patients with Variable Recovery Trajectories After Similar Initial Treatments for Myocardial Infarction
Introduction: Healthy Places Index (HPI) is a California-based, neighborhood-level index comprising 8 domains and 23 socioeconomic metrics on local conditions (e.g., access to educ...
Abstract WE467: Neuro-endocrine markers and Pulse Wave Analyses in young adults with Masked Hypertension: the African-PREDICT study
Background: Sustained physiological stress is an independent cardiovascular risk factor in young adults and may be key in the pathogenesis of masked hypertension (MHT). As stress-i...
Abstract TU148: Predicted Shallow Groundwater Nitrate Concentrations Have Little Effect on the Association between Private Well Use and Rates of Hypertensive Heart Disease, Ischemic Heart Disease, and Stroke/Cerebrovascular Deaths in Alabama
Alabama has the highest age-adjusted CVD mortality in the US. Despite this, our group showed that lower rates of hypertensive heart disease, ischemic heart disease, and stroke/cerebrovascular deaths w...
Abstract TH950: Association between psychological resilience and biological age among early midlife Black women
Background: Black women experience disproportionate exposure to chronic psychosocial stressors that may contribute to accelerated biological aging and heightened cardiovascular dis...
Abstract TU132: Health Behaviors of Middle School Children by Community Type: Metropolitan, Micropolitan, and Rural
Background: Previous research examining differences in health behaviors between urban and rural children has yielded inconsistent results. This study aims to enhance understanding...