Circulation
Articles in this Issue
Abstract P1172: From adverse pregnancy outcome to preventive care: insights from patient interviews on barriers to primary care after adverse pregnancy outcomes, and how to overcome them
Introduction: Primary care is needed to assess and address cardiovascular risk after adverse pregnancy outcomes (APOs) like preeclampsia and gestational diabetes. Yet 40% of individuals wi...
Abstract P1023: Temporal Changes in High-Sensitivity C-Reactive Protein and Risk of Atrial Fibrillation in African Americans: The Jackson Heart Study
Background: Atrial fibrillation (AF) is associated with significant morbidity and mortality. Inflammation plays an important role in AF pathogenesis. The relationship between high-sensitiv...
Abstract P1020: Relationship Between CHA <sub>2</sub> DS <sub>2</sub> -VASc, Health Literacy, and Atrial Fibrillation Knowledge
Introduction: It is unknown how comorbid diagnoses affect patients’ disease-specific knowledge or how patients’ health literacy or numeracy affects this relationship. In patients with atri...
Abstract P1039: Inhibition Of Drug Metabolizing Enzyme Cytochrome P450 2C8 By Acyl-Glucuronide Metabolites Of Gemfibrozil And Clopidogrel.
Human cytochrome P450 (CYP) enzymes are a superfamily of heme-containing oxidoreductases essential in the metabolism of various xenobiotics. CYP2C8 is responsible for the oxidative metabolism of many...
Abstract 028: The Role of Low Physical activity in Exacerbating Global Ischemic Heart Disease: A Three-Decade Global Comprehensive Analysis
Introduction: Ischemic heart disease (IHD) remains one of the leading causes of morbidity and mortality worldwide, with physical inactivity identified as a key modifiable risk factor. This...
Abstract 010: Peripheral Neuropathy is Detected in More than Half of Very Old Adults
Objectives: Emerging evidence suggests peripheral neuropathy (PN) may be more common in older individuals than previously reported, even in the absence of diabetes. However, most studies d...
Abstract P3009: Biomarkers and Risk of Cognitive Impairment in Atrial Fibrillation: The Reasons for Geographic and Racial Differences in Stroke (REGARDS) Cohort
Introduction: Atrial fibrillation (AF) is highly prevalent, and its health effects outside of stroke are under intense study. AF increases dementia risk, but underlying mechanisms are unkn...
Abstract P1053: Impact of Adversity and Birth Outcomes on the Prevalence of Heart-Related Conditions in Children
Background: Adverse childhood experiences (ACEs), social determinants of health, and adverse birth outcomes significantly impact children's well-being. Stress, psychological distress, and...
Abstract P1085: Heart Failure Incidence Among Disaggregated Asian American, Native Hawaiian, and Pacific Islander Subgroups: Insights from the PANACHE Study
Background: Asian American, Native Hawaiian, and other Pacific Islander (AANHPI) persons comprise ~10% of the U.S. population—24 million people—yet a significant gap exists in contemporary...
Abstract P3006: Glycemia and Lipids Profiles Levels, Awareness and Control in the Adult Population: the Italian Health Examination Survey 2023-2024 - CUORE Project
Introduction: WHO recommends monitoring glycemic and lipid profiles in the population to control and prevent NCDs. The target for glycemic/diabetes is to halt the rise within 2025 (2010 as...
Abstract MP11: Association of fixed dose combination therapy use with blood pressure control and cardiovascular outcomes in the Systolic Blood Pressure Reduction Intervention (SPRINT) Trial: A post-hoc analysis
Background: The seminal SPRINT trial demonstrated that intensive blood pressure (BP) control is associated with lower risk of adverse cardiovascular (CV) outcomes. However, BP control amon...
Abstract P2089: Heavy coffee consumption is associated with borderline high risk of coronary heart disease - a meta-analysis
Background: Coffee's global popularity arises from its stimulating effects on the central nervous system, taste, and aroma, making it one of the most widely consumed beverages. Numerous st...
Abstract P3049: Metabolic Measures and Incident Cardiovascular Disease and Mortality: A Pooled Analysis of Multi-ethnic NHLBI Cohorts
Background: The added roles of metabolic measures in health outcomes in racial/ethnic groups in the US remain poorly understood. Pooling data from multi-ethnic cohorts can improve the powe...
Abstract P1173: Opportunities for Intervention: Mental Health and Cardiovascular Health Literacy in Women – Insights from the Research Goes Red Initiative
Introduction: Cardiovascular health literacy (CVHL) is vital for managing cardiovascular risk. However, poor mental health can be a barrier, and there's a gap in understanding how mental h...
Abstract P2136: Prognostic Value of the Six-Minute Walk Test in Patients with Hypertrophic Cardiomyopathy
Background: The six-minute walk test (6MWT) is a simpler, safer, and more cost-effective measure of functional capacity than cardiopulmonary exercise testing (CPET) and can be used for ris...
Abstract P1158: Agreement of Non-Invasive Devices that Measure Pulse Wave Velocity: VaSera vs VICORDER
Background: Adequately assessing subclinical cardiovascular disease (CVD) risk is crucial to mitigate CVD globally. A functional and structural measure of subclinical CVD risk, arterial st...
Abstract P2068: Prevalence of blood pressure control among adults with hypertrophic cardiomyopathy and hypertension
Introduction: Hypertension (HTN) occurs in ~50% of adults with hypertrophic cardiomyopathy (HCM), the most common inherited cardiac disorder. Most individuals with HCM (~70%) have left ven...
Abstract P3008: Plasma Proteomic Signatures Of Organ Aging Are Not Responsive To Exercise Training: HERITAGE Family Study
Introduction: A recent study utilized plasma proteins to identify organ-specific aging signatures that were related to health and disease. However, it is unknown whether exercise intervent...
Abstract P3144: Association Between Perceived Discrimination and Depression/Anxiety Symptoms
Introduction: Research linking perceived discrimination and depression and anxiety symptoms as well as brain function is limited. Objective: T...
Abstract P2097: Association of atrial fibrillation with probable dementia in the SPRINT Trial
Background: Emerging evidence suggests that atrial fibrillation (AF) is associated with cognitive impairment and dementia, though the extent of this relationship in certain populations rem...
Abstract P3075: Diet quality and risk of hypertension in women cancer survivors
Background: Higher diet quality has been associated with reduced hypertension risk in the general population. Although women cancer survivors are at elevated risk of hypertension following...
Abstract P3165: Summary Measure of Social Determinants of Health/Health Equity and Stroke Burden among Mississippi Adults
Background: In 2022, ~97,000 Mississippi adults self-reported receiving a stroke diagnosis. Social determinants of health (SDOH) contribute to stroke burden and associated disparities and...
Abstract P2135: Nicorandil improves health status outcomes in patients with angina pectoris: a prospective, multicenter, cohort study (GREAT)
Background: Coronary artery disease (CAD) is a major contributor to cardiovascular mortality, with angina pectoris affecting nearly half of CAD patients. The GREAT study aims to establish...
Abstract P3074: Metabolomic Insights into Meat Consumption and Blood Pressure: The INTERLIPID Study
Introduction: The westernization and modernization of diet have gradually increased among the Japanese people, resulting in greater consumption of meat. Metabolic profiling can be consider...
Abstract P2085: Variation in Incident Atherosclerotic Cardiovascular Disease Across Asian American, Native Hawaiian and other Pacific Islander Subgroups: The PANACHE Study
Introduction: Atherosclerotic cardiovascular disease (ASCVD) risk varies substantially across racial and ethnic groups, yet few data exist among disaggregated Asian American, Native Hawaii...