Circulation
Articles in this Issue
Abstract P1162: Cardiac Magnetic Resonance Imaging Measures of Atrial Cardiomyopathy and Adverse Clinical Outcomes in the UK Biobank
Introduction: Atrial cardiomyopathy precedes atrial fibrillation (AF) and is a strong risk factor for downstream adverse clinical outcomes, but there is no census about the optimal method...
Abstract P1069: Health Care Professional Perspectives on IMPLEMENT-HF: A Qualitative Study Examining Successes, Facilitators, and Barriers in a Quality Improvement Program for Patients with Heart Failure
Introduction: Heart failure (HF) leads to over 1 million hospitalizations and 450,000 related deaths annually, yet there are substantial quality gaps in care. In 2021, the American Heart A...
Abstract P3146: Racial Disparities in the Association of Adiposity Measures with Cardiovascular Disease Mortality
Introduction: Body Mass Index (BMI) has been generally used to measure adiposity, but it can be inaccurate when examining diverse race groups. We examined how the association between cardi...
Abstract P2014: Baseline Sex Hormone Binding Globulin Level Modifies Intensive Lifestyle Intervention Effect on Blood Pressure in Post-Menopausal Females
Background: The Look AHEAD (Action for Health in Diabetes) randomized controlled trial showed that Intensive Lifestyle Intervention (ILI) targeting weight loss caused greater reductions in...
Abstract P1160: Gut Microbiota, Circulating Inflammatory Markers, and Cardiac Dysfunction In Women Living With HIV
Introduction: The relationships among gut microbial alterations, host inflammation, and cardiac dysfunction remain understudied, particularly in the context of HIV....
Abstract 034: Proteomic Profiles of Obesity-Related Phenotypes are Independently Associated with Incident Cardiovascular Events
Background: Obesity is a critical modifiable risk factor for adverse cardiovascular events, yet traditional measures like Body Mass Index (BMI) have limitations in capturing the complexiti...
Abstract P2078: Extreme Lipoprotein(a) Levels and the Hazard of Acute Myocardial Infarction Among Standard Modifiable Cardiovascular Risk Factors in the United States
Background: Lipoprotein(a) [Lp(a)] is a risk factor for atherosclerotic cardiovascular disease, including acute myocardial infarction (AMI). Currently, no Lp(a) targeted pharmaceutical tre...
Abstract 065: Lower Acute Healthcare Utilization Associated with Virtual Cardiometabolic Health Programs
Background: Type 2 diabetes and hypertension are common and costly conditions that increase risk for hospitalization. Lifestyle-focused virtual health programs may offer an effective and a...
Abstract P2111: Analysis of C-reactive protein omics-measures associates methylation risk score with obstructive sleep apnea-related measures
Introduction: DNA methylation (DNAm) predictors of high sensitivity C-reactive protein (CRP) offer a stable and accurate means of assessing chronic inflammation, bypassing the CRP protein...
Abstract 043: Circulating Monocyte Gene Expression Profiles of Cardiac Remodeling and Incident Heart Failure: the Multi-Ethnic Study of Atherosclerosis
Introduction: The role of circulating monocytes in non-ischemic cardiac remodeling and heart failure (HF) is complex and unclear, due in part to monocyte heterogeneity and plasticity. We a...
Abstract P1004: Epigenetic Age Acceleration Predicts All-cause and CVD-specific Mortality over 20-years in a national-representative population
Background: Epigenetic age acceleration (EAA), the difference between DNA methylation-calculated age (DNAmAge) and chronological age, reflects biological aging. However, few studies have e...
Abstract P2134: Fatigue category, quality of life, and risk of incident clinical heart failure in those with stage B heart failure in the Atherosclerosis Risk in Communities (ARIC) Study.
Background: General and exertional fatigue are common in clinical heart failure (HF) and associated with worse quality of life (QOL) and increased risk of HF re-admission and mortality. Ho...
Abstract P2042: Descriptive Analysis of Geographic and Sociodemographic Patterns in Poor Cardiovascular Health Across U.S. Census Tracts
Introduction: Examining geographic and sociodemographic differences in Poor Cardiovascular Health (PCVH) across U.S. neighborhoods can help identify where the most significant disparities...
Abstract MP37: Proteomics Of Prediabetes Progression And Remission: The Atherosclerosis Risk In Communities (ARIC) Study
Introduction: Proteomics could improve our understanding of the mechanisms underlying short-term prediabetes progression and remission, i.e., reverting to normoglycemia....
Abstract P2132: Impact of Midlife Physical Activity on Multimorbidity in a Rural Setting: Insights from the Bogalusa Heart Study
Introduction: The prevalence of multiple chronic conditions (CCs), especially cardiovascular-related, is increasing, leading to higher disability and mortality. Midlife is a critical perio...
Abstract P2120: Assessing the Accuracy of OpenStreetMap Sidewalk Data: A Comparative Study with Google Street View
Purpose: OpenStreetMap (OSM) serves as an open-and-crowd-sourced geospatial database widely utilized as a data-source in walkability studies, yet its sidewalk data accuracy remains unverif...
Abstract P2144: The Duration of Expectant Management During Hypertensive Disorders of Pregnancy and Blood Pressure 2-7 Years After Delivery
Expectant management of preterm pregnancies with hypertensive disorders (HDP), such as preeclampsia (PE), is standard practice for neonatal benefit, although the effects on the maternal cardiovascular...
Abstract P2146: Multiple Pathways of CD34 <sup>+</sup> Cell Differentiation during Embryogenesis
Introduction: CD34 + progenitor cells are widely used for stem cell therapy for cardiovascular diseases, but the effectiveness of the treatment is variable. To unde...
Abstract P2126: Physical Activity, Inflammation, and Cardiometabolic Risk in Diabetic Kidney Disease: A Population-Based Study
Introduction: Diabetic kidney disease (DKD) increases morbidity and mortality in individuals with diabetes. This study aimed to examine the relationships between cardiometabolic factors, h...
Abstract P2143: Adverse Pregnancy Outcomes – Planning for Fourth Trimester Interventions to Promote Equitable Long-Term Cardiovascular Health
Introduction: Adverse pregnancy outcomes (APOs) are significantly associated with future cardiovascular disease and cardiovascular mortality and disproportionately affect women from minori...
Abstract P2166: Neighborhood-level socioeconomic deprivation associates with monocyte phenotypes involved in atherogenesis: Results from the Multi-Ethnic Study of Atherosclerosis (MESA)
Introduction: Chronic neighborhood stressors contribute to disparate CVD outcomes, with neighborhood socioeconomic deprivation (NSD) linked to inflammation. Separately, relationships have...
Abstract P2142: Hypertensive disorders of pregnancy (HDP) and cardiovascular disease (CVD) in American Indians: The Strong Heart Family Study (SHFS)
Introduction: American Indian populations have high risks of both hypertensive disorders of pregnancy (HDP) and cardiovascular disease (CVD) yet few studies have evaluated associations of...
Abstract P3024: Phenotypic vs. Genetic Mismatch of Body Mass Index and Its Risk Factors: Evidence from the China Kadoorie Biobank and the UK Biobank
Background: The mismatch between phenotypic and genotypic BMI (BMI-PGM) contributes to the sky-rocketing obesity prevalence in both developed and developing countries. However, little is k...
Abstract MP29: Cardiovascular Health Effects of a Free-Sugar-Restricted Diet vs. a Usual Diet: A Randomized Clinical Trial in Adolescent Boys with MASLD
Introduction: High intake of added sugars (>10% total energy) is associated with major cardiovascular risk factors and cardiovascular disease (CVD). Less is known about the effects on c...
Abstract P2130: Identifying Predictors of Achieving 150 Minutes of Weekly Walking in Aging Latinx Adults Enrolled in a 12-month Physical Activity RCT: Insights from Signal Detection Analysis
Physical activity, a key component of Life’s Essential 8, is critical for cardiovascular health, especially among older Latinx adults—a demographic with a high prevalence of at least one cardiovascula...