Circulation
Articles in this Issue
Abstract P2124: Association between accelerometer-corrected physical activity and the prevalence of hypertension, diabetes, and obesity: Results from Korea National Health and Nutrition Examination Survey, 2014-2017
Background: Self-reported measurements have been used as a monitoring approach because it is difficult to objectively assess physical activity levels at a population level. Our aims were t...
Abstract 041: A Novel Machine Learning Strategy to Integrate Multi-Omics Data and Detect Genomic Loci and Gene-Environment Interactions for LDL Cholesterol
Introduction: LDL cholesterol (LDLC) is highly heritable, and understanding its mechanism is crucial for cardiovascular disease treatment and prevention. While multi-omics data is widely a...
Abstract P2106: Serum Metabolomic Markers of Dietary Potassium and Incident Chronic Kidney Disease Risk
Introduction: Potassium is found in many foods and has been inversely associated with incident chronic kidney disease (CKD). Untargeted metabolomic profiling is a powerful approach for dis...
Abstract P2149: Obstructive Sleep Apnea Is Associated With Lower In-Hospital Mortality Among Non-ST Segment Myocardial Infarction Patients With Gender Disparities In Cardiac Intervention
Introduction: Obstructive Sleep Apnea (OSA) is a known risk factor for cardiovascular diseases and has been linked to a higher incidence of non-ST segment elevation myocardial infarction (...
Abstract P3018: Spanish Language Preference is not associated with Prediabetes Risk among Hispanic Adolescents with Overweight or Obesity in an Integrated Healthcare System
Introduction: Nationally, up to 1 in 5 Hispanic adolescents have prediabetes. While obesity and other metabolic risk factors contribute to their disproportionate metabolic risk, fewer stud...
Abstract P3002: Hypoalbuminemia genetic variants are associated with higher cholesterol levels but not atherosclerotic heart disease
Introduction: Secondary hypoalbuminemia is associated with many clinical conditions including hypercholesterolemia, liver disease, kidney disease, and diabetes. These clinical conditions a...
Abstract P1134: Sedentary and Lighter-Intensity Activity Patterns across Trimesters of Pregnancy: the Pregnancy 24/7 Cohort
Background: At least 150 minutes/week of moderate intensity physical activity is recommended during pregnancy, yet pregnancy presents barriers to achieving these guidelines. Some data sugg...
Abstract P3021: Inflammatory Metabolomic Profiles are Associated with Increased Cardiovascular Disease Risk in Women
Background: Cardiovascular disease (CVD) is the leading cause of death worldwide; ischemic stroke (IS) and coronary heart disease (CHD) are the two leading causes of CVD. The burden of CVD...
Abstract MP44: Plasma Proteomic Signature Of BMI Reveals Heterogeneous Cardiometabolic Risk Profiles Within And Across Standard BMI Classifications
Background: The proteome is altered in obesity and proteomic signatures of BMI have been identified. However, few studies have examined differences in clinical profiles between actual and...
Abstract P2101: Association of circulating senescence-associated secretory phenotype (SASP) proteins with the development of frailty in late-life: the Atherosclerosis Risk in Communities (ARIC) Study
Introduction: Emerging evidence suggests a role for cellular senescence in the pathogenesis of adverse late-life outcomes including frailty. Senescence-associated secretory phenotype (SASP...
Abstract P3036: Predicting Risk of Obesity-Related Outcomes in People with Obesity or Overweight: the Role of Social Risk Factors
Introduction: Social risk factors have been shown to be related to overweight/obesity and developing related poor health outcomes. Prediction models for obesity-related outcomes in people...
Abstract MP78: Device-Based Assessment of 24-Hour Activity Across Three Trimesters of Pregnancy: The Pregnancy 24/7 Cohort Study
Introduction: The 24-hour activity cycle, including moderate-to-vigorous intensity physical activity (MVPA), light-intensity physical activity (LPA), sedentary behavior (SED), and sleep, i...
Abstract 060: Associations of Neighborhood Walkability with Baseline Physical Activity and Sedentary Time among US South Asian Adults from the SAHELI Randomized Clinical Trial
Introduction: High neighborhood walkability, defined as presence of crosswalks, sidewalks, and parks, is associated with higher physical activity (PA) and lower sedentary time (ST) among U...
Abstract P3071: Trends in blood pressure among Veterans who initiated antihypertensive medication from 2014 to 2020
Introduction: The prevalence of blood pressure (BP) control of <140/90 mmHg in the Veterans Health Administration (VHA) in the early 2000s was high (>75%). However, the 2017 American...
Abstract P3116: Household Food Insecurity and Adiposity Changes Among Adolescents: A Longitudinal Study of Gender-Specific Outcomes in the Greater Baton Rouge Area
Background: Food insecurity has been consistently linked with obesity in adults, but research findings have been less conclusive among adolescents. Previous studies have suggested that foo...
Abstract P1116: The DASH Dietary Pattern and Risk of Cardiovascular Disease Mortality During 1988-2019 in US Adults: A Population-Based Cohort Study
Introduction: The Dietary Approaches to Stop Hypertension (DASH) diet reduces cardiovascular disease (CVD) risk factors in clinical trials and has been associated with reduced CVD risk. Ho...
Abstract P3127: Loneliness and Social Isolation from Reduced Activities Increase Ischemic Heart Disease Risk via Metabolic and Behavioral Mediators: Evidence from Mendelian Randomization Study
Introduction: Observational studies have linked loneliness or social isolation (SI) to ischemic heart disease (IHD), but results are inconsistent. Moreover, modifiable risk factors mediati...
Abstract P3151: Association Between Life’s Essential 8 and Cardiovascular Disease by Depression Status
Cardiovascular health (CVH), as measured by the American Heart Association's Life’s Essential 8 (LE8) metrics, plays a vital role in determining cardiovascular disease (CVD) risk. Depression is also k...
Abstract 007: Associations of Accelerometer Measures of Physical Activity and Sedentary Behavior with Alzheimer’s Disease Related Dementias and Vascular Dementias Classified Using Medicare Claims Data Among Older Black, Hispanic and White Women: The Objective Physical Activity and Cardiovascular Health Study
Introduction: Higher amounts of physical activity (PA) have been shown to be associated with lower risk of Alzheimer’s disease related dementias (ADRD), however few studies have prospectiv...
Abstract P3141: Psychological Health and Life’s Essential 8 Cardiovascular Health Risk among Women of Reproductive Age
Introduction: Few studies have explored how stress, anxiety, and depression impact cardiovascular health among women of reproductive age. This study examines the relationship between psych...
Abstract P3160: The Effect of Early-Life Area-Level Socioeconomic Deprivation on Cognitive Function in Middle-Aged Adults: Findings from the Bogalusa Heart Study
Background: Area-level socioeconomic deprivation is linked to cognitive impairment in older adults, but its impact from middle age is unclear. Evidence on the early-life deprivation effect...
Abstract P2093: Chronic Kidney Disease Severity and Incident Cognitive Impairment in Patients with Chronic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort
Background: Patients with chronic kidney disease (CKD) face a disproportionate burden of dementia compared to the general population. However, prospective associations between kidney funct...
Abstract 047: Plasma metabolic signatures of healthy diets and healthspan: an integrative analysis of metabolomics and genetics among 12,478 US adults with 32 years of follow-up
Background: Extending the healthspan – years of lived without disease – is a public health priority. Healthy diets have been linked to lower chronic disease risk, but the underlying mechan...
Abstract P3169: Significant Social Determinants of Health Disparities Exist Between Rural and Non-rural Residents with Elevated Blood Pressure: Findings from the LINKED-BP Study
Background: Rural populations face multiple challenges related to social determinants of health (SDOH). However, the extent of these disparities between rural and non-rural residing people...
Abstract P2110: Differences by Race, but not Sex, in Metabolomic Profiles Associated with Red and Processed Meat Consumption in the Coronary Artery Risk Development in Young Adults (CARDIA) Study
Introduction: Higher red and processed meat (RPM) consumption is associated with higher cardiometabolic risk. While consumption patterns vary by sex and race in the US population, it is no...