Circulation
Articles in this Issue
Abstract P3052: Ttitle: Multi-Omic Responses to Low-Calorie Diet Intervention for Remission of Type 2 Diabetes and Individual Variability Short title: Multi-Omics, Low-Calorie Diet, and Diabetes Remission
Introduction: Remission of type 2 diabetes (T2D) can be achieved by a low-calorie diet (LCD) intervention, but molecular mechanisms remain poorly understood. Furthermore, whether responder...
Abstract MP08: The Association of Urinary Sodium with Incident Apparent Treatment Resistant Hypertension among African Americans: Findings from The Jackson Heart Study
Background: Hypertension is a leading cause of cardiovascular disease and disproportionately affects African American (AA) adults, contributing significantly to morbidity and mortality in...
Abstract P2090: Comparison of Medicare Claims Recorded and Surveillance Identified Myocardial Infarction in the Strong Heart Study
Introduction: The Strong Heart Study (SHS) is a cohort study of cardiovascular disease (CVD) in American Indians. Center for Medicare and Medicaid Service (CMS) data may improve CVD outcom...
Abstract P3046: Association of Epigenetic Age Acceleration with Diabetes and Glucose Metabolism Markers Among Hispanic/Latino Adults in The Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
Background: Epigenetic age acceleration (AA) has been associated with diabetes, but associations differ across DNA methylation (DNAm) based epigenetic clocks and populations. We examined w...
Abstract P1033: The Association of Adverse Pregnancy Outcomes with Left Ventricular Structure and Function in Early Midlife: Results from the Bogalusa Heart Study
Background: Studies about the association between the adverse pregnancy outcomes (APO) and cardiac structure and function in midlife are scarce despite evidence that APO increases the risk...
Abstract P2084: Independent prognostic factors of mortality in young patients after STEMI
Young patients (pts) with acute myocardial infarction and ST-segment elevation (STEMI) are a specific subset of a population with different risk factor profiles, clinical presentations, and prognosis...
Abstract P3080: Factor IX and Incident Hypertension in Black and White Adults: The REasons for Geographic and Racial Differences in Stroke (REGARDS) Cohort
Background: A significant fraction of Americans are diagnosed with hypertension. Prior studies have shown Black adults experience a disproportionate amount of this burden. Certain biomarke...
Abstract P2114: Metabolites Associated with Long Term Risk of Peripheral Artery Disease and Critical Limb Ischemia: The Atherosclerosis Risk in Communities (ARIC) Study
Background: Peripheral artery disease (PAD) is a prevalent yet underrecognized vascular condition associated with significant morbidity and mortality. Traditional atherosclerotic risk fact...
Abstract P3061: Uncovering Neighborhood-Level Inequities in Access to Transthoracic Echocardiograms
Methods: From a sample cohort of 274,539 consecutive adults who sought care at Mayo Clinic between 2018-2022, we ascertained demographic and clinical information, including clinically indi...
Abstract P3082: Pregnancy heavy metal, essential element, and micronutrient mixtures and mid-life blood pressure and hypertension: findings from a prospective U.S. pregnancy cohort study with two decades of follow-up
Background: Heavy metals are cardiovascular disease risk factors, while essential elements possess antioxidant and anti-inflammatory properties and are crucial for health at trace levels....
Abstract P2128: Can We Swim Our Way to Better Health? A Cross-sectional National Survey
Background: This study examined obesity and comorbidity rates, physical activity levels, and cardiovascular health, using Life’s Essential 8 (LE8), among the United States Masters Swimming...
Abstract P3106: Association Between Diet Quality, Hypertension, And Hypertension Awareness Among Adults In Puerto Rico
Background: Hypertension (HTN) prevalence in Puerto Rico (PR) is among the highest in the US. Few studies have objectively measured HTN prevalence compared to awareness (i.e., diagnosed) a...
Abstract P3163: Social Determinants of Health Among Rural Underserved Patients with Uncontrolled Hypertension
Introduction: Hypertension remains one of the most prevalent chronic conditions in the United States, with significant racial and ethnic disparities. Similar disparities are also seen amon...
Abstract P2127: AHA Life's essential 8 and ideal cardiovascular health among adult swimmers
Background: This study examined cardiovascular health (CVH), using the American Heart Association Life’s Essential 8 (LE8) scores among the United States Masters Swimming (USMS) adult swim...
Abstract P3057: Interactions Between Coffee Consumption and Genetic Pathways Uncover Biological Mechanisms Related to Type 2 Diabetes Risk Reduction
Introduction: Higher coffee consumption has been consistently associated with lower type 2 diabetes (T2D) risk but the underlying mechanisms are largely unknown. Our prior study showed hig...
Abstract P1014: The associations of financial barriers to dental health care with incident cardiovascular disease and dementia: a longitudinal analysis in the All of Us cohort
Introduction: Though poor oral health is linked to elevated risk of later-life cardiovascular disease (CVD) and Alzheimer’s Disease and Related Dementias (ADRD) via systemic inflammation,...
Abstract P3001: Associations of Biomarkers with Epicardial Adipose Tissue Volume and Density in Cardiovascular Risk Assessment: Insights from the PROMISE Trial
Introduction: Epicardial adipose tissue (EAT) has emerged as a potential biomarker due to its relationship with cardiovascular (CV) events. This study leverages data from the PROMISE trial...
Abstract P3114: Measured Obesity and Overweight in the Adult Population: the Italian Health Examination Survey 2023-2024 - CUORE Project
Introduction: Obesity is associated with an increased risk of non-communicable diseases, such as diabetes, coronary heart disease, stroke, cancers, and other conditions, including obstruct...
Abstract 020: An Innovative HTN Intervention in Partnership with the AHA Promotes Access to Self-Measured Blood Pressure Monitoring in Public Libraries
Background: In response to the 2020 Surgeon General’s call to action for HTN control, this study examines a unique intervention leveraging public libraries to promote self-measured blood p...
Abstract P2160: Exploring Racial and Ethnic Disparities in the Social Determinants of Health among Participants in a Hypertension Prevention Trial, the LINKED-BP Program
Background: Hypertension (HTN) remains a highly prevalent risk factor for cardiovascular disease. To reduce the burden of HTN and advance health equity, social determinants of health (SDOH...
Abstract 045: Genome-wide Association Study for Metabolites in the Tryptophan Metabolism Pathway among African American Patients with Chronic Kidney Disease
Introduction: Impaired tryptophan metabolism is a signature in chronic kidney disease (CKD), leading to adverse cardiovascular outcomes. Genome-wide association studies (GWAS) in CKD patie...
Abstract P1115: A Qualitative Study of Perspectives on South Asian Dietary Practices: Exploring a Framework for Culturally Tailored Food-is-Medicine Interventions
Introduction: South Asians (SA) have a 2-4-fold increased risk of developing cardiometabolic disease (CMD) compared to non-Hispanic Whites in the US. Certain dietary practices (“fried snac...
Abstract P3007: Relationship between ET-1 Gene Polymorphism rs5370 and Cardiovascular Disease among Hispanics Using All of Us data
Background: The Hispanic population in the continental US has grown by 23% over the last decade. Cardiovascular disease (CVD) remains the leading cause of death in this group, affecting 42...
Abstract 008: Effect of a daily multivitamin on 2 year changes in DNA methylation measures of biological aging: Findings from the COSMOS Randomized Clinical Trial
Introduction: Although some trials have reported that multivitamin-multimineral (MVM) supplements reduce age-related chronic conditions such as cancer, cataracts, and cognitive decline amo...
Abstract MP09: Number of incident cardiovascular disease events and deaths prevented among Black adults by achieving blood pressure equity with White adults in the US.
Background: There are preventable disparities in blood pressure (BP) levels by race in the US, that contribute to a higher rate of cardiovascular disease (CVD) events and mortality among n...