Circulation
Articles in this Issue
Abstract P3020: A prognostic molecular signature of hepatic steatosis is spatially heterogeneous and dynamic in human liver
Introduction: The prevalence of hepatic steatosis—a central and early phenotype in multi-system metabolic dysfunction—is increasing in parallel with the obesity pandemic, calling for novel...
Abstract P1094: Patient-Specific Barriers to Establishing Outpatient Heart Failure Care Following Hospitalization
Background: Heart failure (HF) is a complex chronic disease that requires long-term outpatient care. Patients with a high burden of adverse social determinants of health have fewer opportu...
Abstract P3039: A New Biomarker of Aging Derived From Electrocardiogram Improves Risk Prediction of Incident Myocardial Infarction and Stroke.
Introduction: Deep neural networks are increasingly used to generate diagnostic algorithms in cardiovascular medicine. A biomarker of cardiovascular aging, derived from a deep-learning alg...
Abstract P1072: Underutilization of Novel Guideline-Directed Medical Therapy in Patients with Heart Failure
Background: Guideline directed medical therapy (GDMT) for patients with heart failure (HF) now includes SGLT2i and ARNI regardless of ejection fraction. Despite strong evidence supporting...
Abstract P3040: Associations between Triglyceride-glucose-obesity Indicators with Cardiovascular Disease Across Combination of Body Mass Index and Central Obesity Categories: The China Health and Retirement Longitudinal Study
Introduction: The triglyceride glucose-body mass index (TyG-BMI) and triglyceride glucose-waist circumference (TyG-WC) are fast and simple clinical indices with proven reliability in predi...
Abstract 042: Estimating the effect of menopausal hormone therapy on CVD risk among women with vasomotor symptoms: A target trial emulation within the SWAN Study
Introduction: Frequent and/or persistent vasomotor symptoms (VMS) are associated with cardiovascular disease (CVD) risk. Although menopausal hormone therapy (HT) is the standard treatment...
Abstract P3037: Racial and Ethnic Disparities in Cardiovascular Outcomes and the Role of Physical Activity and Sleep as Mediators: 2011-2020 National Health and Nutrition Examination Survey
Background: Cardiovascular Disease (CVD) - including coronary artery disease, heart failure, stroke, and hypertension - disproportionately affects Black and Hispanic populations. However,...
Abstract 067: Long-term Cardiovascular Outcomes After COVID-19 Hospitalization in the Omicron Era: Retrospective Cohort Study
Introduction: Hospitalization for COVID-19 in the Pre-Omicron era was associated with an increased risk of major adverse cardiovascular events (MACE), but data from the Omicron era are spa...
Abstract P3159: Long-term and recurrent antibiotic use during early life is associated with incident cardiovascular disease during adulthood
Background: Long-term antibiotic use during adulthood has been associated with a high risk of cardiovascular disease (CVD) in adults. However, it remains unclear whether antibiotic use dur...
Abstract P1052: Metabolomics signatures of childhood cardiovascular risk factor burdens associate with midlife cognitive function: Findings from the Bogalusa Heart Study
Introduction: The excess childhood burden of cardiovascular risk factors (CVRFs) is linked to poorer midlife cognitive performance, independent of adult exposure. Despite the importance of...
Abstract P3096: Barriers Associated with The Use of Smart Blood Pressure Monitors Among Minority Older Adults
Background: Smart blood pressure monitors (SBPMs) are increasingly used among older adults to monitor hypertension, improve health and independence, and decrease hospitalization cost. Howe...
Abstract P1001: Life-course Epidemiology of Cardiovascular-related Factors and Pace of Aging, Insights from Age Gene/Environment Susceptibility-Reykjavik Longitudinal Study
Background: Biological aging reflects the age and physiological function of cells and tissues. In this study, we examined the potential long-term influence of cardiovascular-related factor...
Abstract 074: Interplays of ADH1B Genotype, Alcohol Consumption, and Gut Microbiota in Relation to Insulin Resistance
Background: Alcohol consumption has been linked to alterations in gut microbiota and insulin resistance. The alcohol dehydrogenase 1B ( ADH1B) gene plays a crucial...
Abstract P1093: Race, Sex, and SES Differences in Heart Failure Incidence: A Cross-Cohort Collaboration
Background: Health disparities regarding heart failure (HF) incidence by age, race, sex at birth, socioeconomic status (SES) and their intersections remain under-researched....
Abstract P2010: Extra-Coronary Calcification and Risk of Incident Cardiovascular Disease in Adults 75 and Older: The Atherosclerosis Risk in Communities (ARIC) Study
Background: The coronary artery calcium (CAC) score is one of the most potent predictors of cardiovascular disease (CVD). During a CAC scan, extra-coronary calcification (ECC) can be simul...
Abstract P1098: Serum Metabolites and Heart Failure Risk: the Multi-Ethnic Study of Atherosclerosis and the Rotterdam Study
OBJECTIVE To examine the association between serum metabolites and incident heart failure (HF) and to assess the added value of identified metabolites for 10-year HF risk prediction....
Abstract P2027: Associations Between Paraben Exposure and Cardiometabolic Outcomes in Pediatric Populations: A Systematic Review
Introduction: Parabens are antimicrobial chemicals frequently used as preservatives in consumer products. Due to their chemical structure, exposure to parabens may impact cardiometabolic h...
Abstract P2021: Association between Alcohol Consumption and the Risk of Cardiovascular Events by Renal Function Status in Japanese Community Dwellers
Introduction: The association between alcohol consumption and cardiovascular events differs according to the presence or absence of cardiovascular risk factors such as hypertension or dysl...
Abstract P1112: Improving School Food: A Novel Tool to Identify Priorities for Effective Policy Change in Nepal School Environments
In Nepal, four noncommunicable diseases (NCDs) (cardiovascular disease, cancer, chronic respiratory disease, and diabetes) account for over half of total mortality. Diet is a modifiable risk factor fo...
Abstract MP28: Healthy Eating for the Planet, Cardiovascular Health, and Longevity: An Observational Study
Introduction: There is insufficient evidence on the impact of the environmentally sustainable diet proposed by the EAT- Lancet Commission on cardiovascular disease...
Abstract P2100: Longitudinal association between MIND diet adherence, inflammatory mechanism, and cognitive health
Introduction: Evidence is limited on the cognitive benefits of the Mediterranean-DASH Intervention for Neurodegenerative Delay(MIND) diet and biological mechanism for middle-age adults. We...
Abstract P3059: Exploring Genetic Ancestry, Socioeconomic and Acculturation Factors in Hispanic/Latino Hypertrophic Cardiomyopathy Genotype Carriers: Insights from the Hispanic Community Health Study / Study of Latinos (HCHS-SOL)
Introduction: Hypertrophic Cardiomyopathy (HCM) is associated with rare sarcomeric variants. Little is known about the profiles of HCM sarcomeric variant carriers in diverse populations, p...
Abstract P3084: Yield of Various Recruitment Approaches for an Observational Cohort of Patients with Heart Failure with Preserved Ejection Fraction: A Single Center Experience from HeartShare
Introduction: The HeartShare Network aims to improve understanding of heart failure with preserved ejection fraction (HFpEF), a condition that disproportionately affects those with adverse...
Abstract P1087: Impact of Allostatic Load on Prevalent and Incident Pre-Heart Failure in the Echocardiographic Study of Latinos (ECHO-SOL)
Introduction: Allostatic load (AL) is multi-system index that physiologically quantifies the effects of chronic stress. The relationship of AL to pre-heart failure (HF), a precursor of cli...
Abstract P3154: Out-Of-Hospital Pediatric Cardiac Arrest, Survival, And Associated Factors – A Systematic Review And Meta-Analysis
Introduction: Pediatric out-of-hospital cardiac arrest (OHCA) is associated with poor survival and neurological outcomes. Large variations in the incidence and survival have been reported...