Circulation
Articles in this Issue
Abstract P3030: Associations of Co-Existing Hypertension and Diabetes with Mortality Risk in US Adults: A Prospective Analysis of the 1999-2018 National Health and Nutrition Examination Surveys
Introduction: Hypertension (HTN) and type 2 diabetes (T2D) prevalence is on the rise resulting in an increasing number of US adults living with multiple cardiometabolic morbidities. The as...
Abstract P1084: Association of Body Composition and Incident Heart Failure and Heart Failure with Preserved Ejection Fraction and Heart Failure with Reduced Ejection Fraction in postmenopausal women
Background: As the US population ages, Heart Failure (HF) is reaching epidemic proportions, with heart failure with preserved ejection fraction (HFpEF) placing a particular burden on elder...
Abstract P2028: Air Pollution Induces Atrial Fibrosis via CARD9-Mediated Immune Response
Background: Exposure to ambient fine particulate matter (PM) triggers systemic inflammation and is associated with atrial fibrosis (AF) and cardiac arrhythmia. The cytosolic adaptor caspas...
Abstract P3077: Pro-Enkephalin A and Risk of Incident Hypertension: The REasons for Geographic and Racial Differences in Stroke (REGARDS) Study
Introduction: Hypertension, a risk factor for cardiovascular disease and chronic kidney disease, poses a significant burden in the U.S, especially among Black U.S. adults. Higher pro-enkep...
Abstract P1120: Association Between Depression and Movement Behaviors with Risk of Mortality among people with Arthritis: The National Health and Nutrition Examination Survey (NHANES) 2007-2016
Arthritis is a chronic inflammatory disease characterized by joint pain, swelling and limited range of motion. Depression is prevalent among individuals with arthritis and is associated with increased...
Abstract P2107: Sex-Specific Associations of Plasma Proteins with HF Risk: The Atherosclerosis in Communities (ARIC) Study
Introduction: Heart failure (HF) epidemiology and pathophysiology differ by sex. Large scale plasma proteomics offers promise to provide insight into biologic mechanisms underlying sex-bas...
Abstract P3170: Identifying moderate to severe food insecurity among hypertensive patients in a low and middle-income Caribbean country
Introduction: The Caribbean is experiencing a high burden from food insecurity (FI) and cardiovascular disorders including hypertension. Hypertensive patients with FI need to be easily ide...
Abstract P2032: Associations of Volatile Organic Compound Metabolites with Urinary Catecholamines: A Cross-Sectional Study with Green Heart Louisville
Volatile organic compounds (VOCs) are ubiquitous gaseous chemicals present in indoor and outdoor air. These compounds are emitted from several sources such as automobiles, paints, and household items....
Abstract 019: Association Of Sleep Irregularity And Variability With Leptin And Adiponectin Levels In Adolescents
Introduction: Hormone fluctuations and circadian rhythms, including the sleep-wake cycle, are reciprocally associated. Lipid and glucose metabolism pace depend on leptin and adiponectin le...
Abstract 015: Sleep Health and Cardiometabolic Risk in Health Care Workers: The role of heart rate and heart rate variability
Purpose: Despite strong evidence linking poor sleep with cardiometabolic risk, underlying mechanisms are poorly understood, limiting interventions to improve sleep&cardiometabolic heal...
Abstract P1035: The Association between PREVENT 10-Year Overall Cardiovascular Disease Risk and Incident Fractures in Postmenopausal Women
Background: This study aimed to estimate the association between cardiovascular disease (CVD) risk and incident fracture in postmenopausal women. Methods:...
Abstract P1136: Fetal C-Reactive Protein rs1205 Genotype Associated with Maternal Pre-eclampsia
Introduction: Maternal variants including C-Reactive Protein, CRP rs1205 have previously been associated with risk of pre-eclampsia (PE). These findings were replic...
Abstract MP64: PREVENT 30-Year CVD Risk During Pregnancy Is Associated With Inflammatory and Vascular Placental Pathology
Introduction: Many adverse pregnancy outcomes (APOs) associated with long-term CVD risk, such as preeclampsia, are mediated by placental function. Notably, the vascular and inflammatory pl...
Abstract P2049: Race and Ethnicity and Oral Anticoagulation Adherence in Older Adults with Atrial Fibrillation: A Nationwide Study
Background: Atrial fibrillation (AF) is the most common arrhythmia and is associated with morbidity from ischemic stroke. Oral anticoagulant (OAC) therapy reduces stroke risk. Prior work h...
Abstract P1005: Associations between circulating reproductive hormones and cardiovascular-kidney-metabolic syndrome in older men
Introduction: The American Heart Association (AHA) recently introduced the cardiovascular-kidney-metabolic (CKM) syndrome as a systemic disorder with connections among heart disease, kidne...
Abstract P1119: Model-based Replacement of Sedentary Time with Light Intensity Physical Activity is Associated with Improved Cardiometabolic Risk Score over 15 Years of Midlife in the CARDIA Study
Introduction: Current physical activity (PA) recommendations support replacing time spent sedentary with PA of any intensity. Replacing sedentary time with light intensity PA (LPA) may be...
Abstract P3048: Relationships of Body Roundness Index and Triglyceride–glucose Index with 5-year All-cause Mortality in Patients with Diabetes and Comorbid Hypertension: Evidence from Two Prospective Cohort Studies
Aims: We aimed to characterise the complex relationships of body roundness index (BRI) and triglyceride-glucose index (TyG) with 5-year all-cause mortality in patients with diabetes and co...
Abstract P2158: Neighborhood poverty, John Henryism, and incident cardiovascular disease events in the Jackson Heart Study
Background: John Henryism (JH), or high effort-coping, is common when facing adversity. Little is known about cardiovascular disease (CVD) risk when living in poverty and having to cope wi...
Abstract 005: Plasma Senescence-Associated Secretory Phenotype (SASP) Proteins are Associated with the Development of Cognitive Impairment in Late Life: the ARIC study
Introduction: The senescence-associated secretory phenotype (SASP) consists of paracrine signaling molecules with deleterious effects secreted by senescent cells. However, little human dat...
Abstract MP13: Insomnia with Objective Short Sleep Duration is Associated with Hypertension in Adolescents
Introduction: Several studies have examined the association between insomnia and short sleep duration with elevated blood pressure (eBP) and stage 2 hypertension (HTN) in middle-aged adult...
Abstract P2051: Community-academic partnership to optimize retention in a hypertension prevention trial in Black Men
Background: Black adults, particularly Black men are underrepresented in cardiovascular research studies, limiting interpretation and generalization of findings, adversely impacting health...
Abstract 021: The Effectiveness of a Community Health Worker-Led Intensive Blood Pressure Intervention on Coronary Heart Disease and Heart Failure
Background: Coronary heart disease (CHD) and heart failure are increasing in China and represent significant public health and economic challenges. Although community health worker (CHW)-l...
Abstract P2098: The Interaction of Vascular Risk Factors in Midlife and Late-life on Incident Dementia: The Atherosclerosis Risk in Communities Neurocognitive Study
Introduction: Vascular risk factors of hypertension, diabetes, and smoking in midlife (45-64 years) and possibly early late-life (65-74 years) are associated with increased risk of dementi...
Abstract MP18: Association of Sleep Duration with Cardiac Structure and Function in African Caribbeans: a preliminary report from the Tobago Heart Study
Emerging evidence suggests a potential relationship between sleep and cardiac abnormalities, even in the absence of apnea. Therefore, we aimed to test the association of sleep duration and cardiac str...
Abstract MP03: Metabolite Signature of Ultra-processed Foods Intake and Cardiovascular Morbidity and Mortality Among Low-income Black and White Americans
Background: High ultra-processed foods (UPF) intake may increase risks of CVD morbidity and mortality, but the mechanisms are unclear, and there is no biomarker for UPF intake. We aimed to...