Chordin-Like 1 mRNA Therapy for Acute Myocardial Infarction

Mateusz Tomczyk; Izabela Kraszewska; Gang Li; Matthew John Hayes; Luca Venditti; Josef Huntington; Chun Kit Wong; Angelica Cadoni; Francesca Bortolotti; Antonio Mura; Manendra Pachauri; Gianfranco Sinagra; Mauro Giacca

doi:10.1161/circulationaha.125.074078

Chordin-Like 1 mRNA Therapy for Acute Myocardial Infarction

M Mateusz Tomczyk (School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King’s College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).) I Izabela Kraszewska (School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King’s College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).) G Gang Li (State Key Laboratory of Molecular Reaction Dynamics and Dalian Coherent Light Source Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China) M Matthew John Hayes (Institute of Ophthalmology, University College London, London, United Kingdom (M.J.H.).) L Luca Venditti (School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King’s College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).) J Josef Huntington (School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King’s College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).) C Chun Kit Wong (School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King’s College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).) A Angelica Cadoni (School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King’s College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).) F Francesca Bortolotti (Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy (F.B., A.M., M.P., M.G.).) A Antonio Mura (Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy (F.B., A.M., M.P., M.G.).) M Manendra Pachauri (Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy (F.B., A.M., M.P., M.G.).) G Gianfranco Sinagra M Mauro Giacca (Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy (F.B., A.M., M.P., M.G.).)

View Original

APA MLA Chicago BibTeX RIS

Article Details

Journal Circulation

Volume / Issue Vol. 152, Issue 22

Published December 02, 2025

Pages 1586-1589

DOI 10.1161/circulationaha.125.074078

ISSN 0009-7322

Publisher Lippincott Williams & Wilkins

Journal Info

Circulation

Lippincott Williams & Wilkins

ISSN: 0009-7322 Health Sciences

Authors (13)

M

Mateusz Tomczyk

School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King’s College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).

I

Izabela Kraszewska

School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King’s College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).

G

Gang Li

State Key Laboratory of Molecular Reaction Dynamics and Dalian Coherent Light Source Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China

M

Matthew John Hayes

Institute of Ophthalmology, University College London, London, United Kingdom (M.J.H.).

L

Luca Venditti

School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King’s College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).

J

Josef Huntington

School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King’s College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).

C

Chun Kit Wong

School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King’s College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).

A

Angelica Cadoni

School of Cardiovascular and Metabolic Medicine and Sciences and BHF Centre for Research Excellence and Medical Research Council/British Heart Foundation Centre of Research Excellence in Advanced Cardiac Therapies, King’s College London, London, United Kingdom (M.T., I.K., G.L., L.V., J.H., C.K.W., A.C.).

F

Francesca Bortolotti

Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy (F.B., A.M., M.P., M.G.).

A

Antonio Mura

Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy (F.B., A.M., M.P., M.G.).

M

Manendra Pachauri

Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy (F.B., A.M., M.P., M.G.).

G

Gianfranco Sinagra

M

Mauro Giacca

Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy (F.B., A.M., M.P., M.G.).

Chordin-Like 1 mRNA Therapy for Acute Myocardial Infarction

Article Details

Journal Info

Authors (13)

Related Articles from this Journal

Occupational Radiation Safety in Electrophysiology During Pregnancy: Evaluating Uterine Radiation Doses During Catheter Ablations and Device Implantations

Response by Rogers et al to Letter Regarding, “Deep Learning-Based Continuous QT Monitoring to Identify High-Risk Prolongation Events After Class III Antiarrhythmic Initiation”

Clinical Cardiology at the Crossroads: Perspectives on the Next Era at <i>Circulation</i>

ABHD11-Mediated mtDNA Transcription Restored Mitochondrial Function to Attenuate Cardiomyocyte Ferroptosis After Myocardial Infarction

Letter by Li et al Regarding Article, “Deep Learning-Based Continuous QT Monitoring to Identify High-Risk Prolongation Events After Class III Antiarrhythmic Initiation”