Journal of Biological Chemistry

The role of human Shu complex in ATP-dependent regulation of RAD51 filaments during homologous recombination–associated DNA damage response

Sam S.H. Chu, Guangxin Xing, Hong Ling Jun 01, 2025 pp. 110212 10.1016/j.jbc.2025.110212

Nrf2-and p53-inducible REDD2/DDiT4L/Rtp801L confers pancreatic β-cell dysfunction, leading to glucose intolerance in high-fat diet-fed mice

Yukiho Yamada, Natsuho Urakawa, Hisato Tamiya et al. Jun 01, 2025 pp. 110271 10.1016/j.jbc.2025.110271

Bile acids inhibit equilibrative adenosine transport to alter adenosine receptor signaling in cholestasis

Arnav Joshi, Sijie Chen, Fazlur Md Rahman et al. Jun 01, 2025 pp. 108563 10.1016/j.jbc.2025.108563

Conditional lethality and suppressor analysis of plasmid-based temperature-sensitive fabZ expression in Pseudomonas aeruginosa

Zhenhua Chen, Junpeng Lu, Qinghai Tang et al. Jun 01, 2025 pp. 108553 10.1016/j.jbc.2025.108553

Smooth muscle Cxcl12 contributions to vascular remodeling in flow and hypoxia-induced pulmonary hypertension

Timothy Klouda, Savas T. Tsikis, Thomas I. Hirsch et al. Jun 01, 2025 pp. 110207 10.1016/j.jbc.2025.110207

NOTCH2 disrupts the synovial fibroblast identity and the inflammatory response of epiphyseal chondrocytes

Ernesto Canalis, Rosa Guzzo, Lauren Schilling et al. Jun 01, 2025 pp. 110206 10.1016/j.jbc.2025.110206

The transcriptional regulator Sin3a activates CD44 and promotes collective luminal breast cancer cell migration

Yaqi Qiu, Guangxin Luan, Yiwen Liu et al. Jun 01, 2025 pp. 110264 10.1016/j.jbc.2025.110264

CRAC channel activity pulsates during cytosolic Ca2+ oscillations

Yu-Ping Lin, Erica Scappini, Gary R. Mirams et al. Jun 01, 2025 pp. 108519 10.1016/j.jbc.2025.108519

High uric acid exacerbates nonalcoholic steatohepatitis through NLRP3 inflammasome and gasdermin D-mediated pyroptosis

Zixin Xu, Chenxi Tang, Xin Song et al. Jun 01, 2025 pp. 110249 10.1016/j.jbc.2025.110249

The ribonuclease RNase T2 mediates selective autophagy of ribosomes induced by starvation in Saccharomyces cerevisiae

Atsushi Minami, Kohei Nishi, Rikusui Yamada et al. Jun 01, 2025 pp. 108554 10.1016/j.jbc.2025.108554

ProOvErlap: Assessing feature proximity/overlap and testing statistical significance from genomic intervals

Nicolò Gualandi, Alessio Bertozzo, Claudio Brancolini Jun 01, 2025 pp. 110209 10.1016/j.jbc.2025.110209

Evidence of bidirectional transmembrane signaling by the sensor histidine kinase GacS from Pseudomonas aeruginosa

Safoura Salar, Steve Silletti, Florian D. Schubot Jun 01, 2025 pp. 108521 10.1016/j.jbc.2025.108521

A SUMO-interacting motif in the guanine nucleotide exchange factor EPAC1 is required for subcellular targeting and function

Wenli Yang, Fang Mei, Wei Lin et al. Jun 01, 2025 pp. 110279 10.1016/j.jbc.2025.110279

Circadian clock-independent ultradian rhythms in lipid metabolism in the Drosophila fat body

Blanca Lago Solis, Rafael Koch, Emi Nagoshi Jun 01, 2025 pp. 110245 10.1016/j.jbc.2025.110245

An uncharacterized gene from the Actinobacillus genus encodes a glucosyltransferase with successive transfer activity and unique substrate specificity

Takahiro Yamasaki, Daisuke Kohda Jun 01, 2025 pp. 108567 10.1016/j.jbc.2025.108567

Key amino acids in RNA polymerase and helicase proteins regulate RNA synthesis efficiency in porcine reproductive and respiratory syndrome virus

Hui Li, Riteng Zhang, Honglin Xie et al. Jun 01, 2025 pp. 110247 10.1016/j.jbc.2025.110247

CaV3.3 T-type calcium channels contribute to carboplatin resistance in retinoblastoma

Sooyun Kim, Chang Sik Cho, Ha Young Jang et al. Jun 01, 2025 pp. 108535 10.1016/j.jbc.2025.108535

Specific phosphoinositide interaction of Jps1 is a key feature during unconventional secretion in Ustilago maydis

Sanchi Dali, Michèle Schultz, Marian Köster et al. Jun 01, 2025 pp. 110215 10.1016/j.jbc.2025.110215

Symmetric stimulation of Hsp90 catalyzed ATP hydrolysis through enhanced active site gate dynamics

Breanna Magnan, Thomas Dumont, Suad Rashid et al. Jun 01, 2025 pp. 110262 10.1016/j.jbc.2025.110262

Fatty acyl-CoA reductase FAR1 is essential for the testicular seminolipid synthesis required for spermatogenesis and male fertility

Ayano Tamazawa, Tatsuro Naganuma, Kento Otsuka et al. Jun 01, 2025 pp. 108538 10.1016/j.jbc.2025.108538

Antioxidant capacity of the iron–sulfur cluster assembly protein IscU2 is mediated by aspartate metabolism to promote tumor survival

Xunjun Yang, Na Liang, Dandan Liu et al. Jun 01, 2025 pp. 110234 10.1016/j.jbc.2025.110234

Delayed inactivation of TRPC6 as a determinative characteristic of FSGS-associated variants

Ryo Okada, Reiko Sakaguchi, Tatsuya Komaki et al. Jun 01, 2025 pp. 110256 10.1016/j.jbc.2025.110256

Alisertib impairs the stemness of hepatocellular carcinoma by inhibiting purine synthesis

Zhuoran Qi, Jie Luo, Wenfeng Liu et al. Jun 01, 2025 pp. 108558 10.1016/j.jbc.2025.108558

The ubiquitin ligase NKLAM promotes apoptosis and suppression of cell growth

Paul A. Willard, Jacki Kornbluth Jun 01, 2025 pp. 108527 10.1016/j.jbc.2025.108527

Identification and design principles of far-red–absorbing chlorophyll in the light-harvesting complex

Keisuke Saito, Makiko Kosugi, Linhao Qiu et al. Jun 01, 2025 pp. 108518 10.1016/j.jbc.2025.108518