Journal of Biological Chemistry

Cell targeting by the bicomponent leukocidin subunit HlgB drives Staphylococcus aureus pathophysiology

Julia Sproch, Rachel Prescott, Hee Jin Kim et al. Oct 01, 2025 pp. 110592 10.1016/j.jbc.2025.110592

Argonaute 1 contributes to the transcriptional silencing of HIV-1

Sophie Goudey, Melissa Ait Said, Juliette Desforges et al. Oct 01, 2025 pp. 110612 10.1016/j.jbc.2025.110612

CLIC5A binds to and stabilizes the open and active conformation of ezrin

Md. Mizanur Rahman, Jong S. Kim, Laiji Li et al. Oct 01, 2025 pp. 110646 10.1016/j.jbc.2025.110646

Chromatin deactivation in pregranulosa cells contributes to primordial follicle formation

Xuzhao Wang, Xin Qiu, Yuxiao Ma et al. Oct 01, 2025 pp. 110598 10.1016/j.jbc.2025.110598

Dissecting the Cdc37 cochaperone code: Functional roles in chaperone-mediated stress adaptation

Megan M. Mitchem, Ashley Choi, Duhita A. Mirikar et al. Oct 01, 2025 pp. 110672 10.1016/j.jbc.2025.110672

Cysteine redoxome landscape in the liver of male mice fed a high-fat high-sucrose diet

Cynthia M. Galicia-Medina, Hein Ko Oo, Takumi Nishiuchi et al. Oct 01, 2025 pp. 110730 10.1016/j.jbc.2025.110730

Defined media reveal the essential role of lipid scavenging in supporting cancer cell proliferation

Oliver J. Newsom, Eric Zheng, Lucas B. Sullivan Oct 01, 2025 pp. 110693 10.1016/j.jbc.2025.110693

ARHGAP10 is a novel microtubule-associated protein that regulates the resorption activity of osteoclasts

Laura Jentschel, Anne Blangy, Guillaume Bompard Oct 01, 2025 pp. 110668 10.1016/j.jbc.2025.110668

Andrographolide modulates glucose metabolism in visceral adipose tissue in an Alzheimer's disease obese mouse model

Paulina Ormazabal, Camila Gherardelli, Cristina Pinto et al. Oct 01, 2025 pp. 110607 10.1016/j.jbc.2025.110607

Mapping cellular cytosolic pH in vivo under physiological and pathophysiological conditions

Shuwei Zhang, Xiaoxin Hu, Bowen Zhang et al. Oct 01, 2025 pp. 110637 10.1016/j.jbc.2025.110637

Annexin A2 interferes with complement regulation within the glomerulus

Brandon Renner, Jennifer Laskowski, Felix Poppelaars et al. Oct 01, 2025 pp. 110657 10.1016/j.jbc.2025.110657

Key roles in copper efflux and protein homeostasis of the intrinsically disordered region of a bacterial outer membrane channel

Amira Khochtali, Marine Ote, Hugo Bâlon et al. Oct 01, 2025 pp. 110670 10.1016/j.jbc.2025.110670

The cytoplasmic domain of the pseudoprotease iRhom2 mediates distinct signaling mechanisms to control activation of the cell surface protease ADAM17

Fangfang Lu, Marjorie Fournier, Matthew Freeman Oct 01, 2025 pp. 110643 10.1016/j.jbc.2025.110643

Structural bias in vitamin A metabolism: Why α-retinoids miss the eye

Sepalika Bandara, Aicha Saadane, Pranesh Ravichandran et al. Oct 01, 2025 pp. 110713 10.1016/j.jbc.2025.110713

Withdrawal: A regulatory role for p38δ MAPK in keratinocyte differentiation: Evidence for p38δ-ERK1/2 complex formation

Tatiana Efimova, Ann-Marie Broome, Richard L. Eckert Oct 01, 2025 pp. 110619 10.1016/j.jbc.2025.110619

Platelet Jak2 deficiency accelerates atherosclerosis with increased inflammatory response

Daeun Kim, Yu Zhe Li, Jiaqi Yang et al. Oct 01, 2025 pp. 110603 10.1016/j.jbc.2025.110603

MilM from mildiomycin biosynthesis is an oxygen-, pyridoxal phosphate-dependent arginine hydroxylase

Kairel E.K. Edwards, Megan E. Wolf, Lindsay D. Eltis et al. Oct 01, 2025 pp. 110605 10.1016/j.jbc.2025.110605

Degradation of CaMKII is stimulated by its active conformation

Christina Quasney, Leslie C. Griffith Oct 01, 2025 pp. 110601 10.1016/j.jbc.2025.110601

BR-bodies facilitate adaptive responses and survival during copper stress in Caulobacter crescentus

Christie Passos, Dylan T. Tomares, Hadi Yassine et al. Oct 01, 2025 pp. 110648 10.1016/j.jbc.2025.110648

WNT7A/B assemble a GPR124-RECK-LRP5/6 coreceptor complex to activate β-catenin signaling in brain endothelial cells

Robin Heiden, Laura Hannig, Calvin J. Kuo et al. Oct 01, 2025 pp. 110682 10.1016/j.jbc.2025.110682

A small-sized imidazole-derived ligand binds to the KRAS promoter G-quadruplex and inhibits cancer growth with enhanced immunomodulation

Xiao-Dong Wang, Qian-Wen Nie, Ming-Hao Hu Oct 01, 2025 pp. 110647 10.1016/j.jbc.2025.110647

Quantitative parameters of productive transcription on T5 N25–based promoters are modulated by the initial transcribed sequence and template supercoiling

Lilian M. Hsu, N. Natalie Han Oct 01, 2025 pp. 110610 10.1016/j.jbc.2025.110610

Catalytic region mimetics in Na+/H+ exchanger regulatory factor 4 suppress guanylate cyclase 2C activity to regulate enterotoxin triggered diarrhea

Yashaswini Ramananda, Pramodha Liyanage, Yunjie Huang et al. Oct 01, 2025 pp. 110559 10.1016/j.jbc.2025.110559

Phosphoglycerate dehydrogenase interacts with and inhibits the protein kinase TAK1 to mitigate septic shock

Penghui Hu, Zemin Ji, Hui Xiong et al. Oct 01, 2025 pp. 110658 10.1016/j.jbc.2025.110658

Correction: Curcumin suppresses AP1 transcription factor-dependent differentiation and activates apoptosis in human epidermal keratinocytes

Sivaprakasam Balasubramanian, Richard L. Eckert Oct 01, 2025 pp. 110625 10.1016/j.jbc.2025.110625