Journal of Biological Chemistry

Metabolic control of luteinizing hormone-responsive ovarian steroidogenesis

Emilia Przygrodzka, Fatema Bhinderwala, Robert Powers et al. Jan 01, 2025 pp. 108042 10.1016/j.jbc.2024.108042

High-affinity ELR+ chemokine ligands show G protein bias over β-arrestin recruitment and receptor internalization in CXCR1 signaling

Katrijn Boon, Nathan Vanalken, Martyna Szpakowska et al. Jan 01, 2025 pp. 108044 10.1016/j.jbc.2024.108044

Structural basis for Rab23 activation and a loss-of-function mutation in Carpenter syndrome

Yat Yin Chau, Hanbin Liang, Wai Lam Tung et al. Jan 01, 2025 pp. 108036 10.1016/j.jbc.2024.108036

An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck

Ari M. Selzer, Gabriella Gerlach, Giancarlo Gonzalez-Areizaga et al. Jan 01, 2025 pp. 108088 10.1016/j.jbc.2024.108088

Prohibitin 1 tethers lipid membranes and regulates OPA1-mediated membrane fusion

Tadato Ban, Kimiya Kuroda, Mitsuhiro Nishigori et al. Jan 01, 2025 pp. 108076 10.1016/j.jbc.2024.108076

Apoptotic signaling by TNFR1 is inhibited by the α2-6 sialylation, but not α2-3 sialylation, of the TNFR1 N-glycans

Jihye Hwang, Tejeshwar C. Rao, Jiahui Tao et al. Jan 01, 2025 pp. 108043 10.1016/j.jbc.2024.108043

Aberrant Wnt/β-catenin signaling in the mesenchymal stem cells of LZTFL1-depleted mice leads to increased adipogenesis, with implications for obesity

Yunden Badralmaa, Ven Natarajan Jan 01, 2025 pp. 108057 10.1016/j.jbc.2024.108057

The mode of subunit addition regulates the processive elongation of actin filaments by formin

Biswaprakash Mahanta, Naomi Courtemanche Jan 01, 2025 pp. 108071 10.1016/j.jbc.2024.108071

Small molecule-based regulation of gene expression in human astrocytes switching on and off the G-quadruplex control systems

Vijay Kumar M. J, Jérémie Mitteaux, Zi Wang et al. Jan 01, 2025 pp. 108040 10.1016/j.jbc.2024.108040

One-for-all gene inactivation via PAM-independent base editing in bacteria

Xin Li, Ying Wei, Shu-Yan Wang et al. Jan 01, 2025 pp. 108113 10.1016/j.jbc.2024.108113

The steroid hormone 20-hydroxyecdysone inhibits RAPTOR expression by repressing Hox gene transcription to induce autophagy

Tian-Wen Liu, Can Tian, Yan-Xue Li et al. Jan 01, 2025 pp. 108093 10.1016/j.jbc.2024.108093

Redirecting E3 ubiquitin ligases for targeted protein degradation with heterologous recognition domains

Huan Yang, Ge Zheng, Grace Y. Li et al. Jan 01, 2025 pp. 108077 10.1016/j.jbc.2024.108077

Spatial chromosome organization and adaptation of the radiation-resistant extremophile Deinococcus radiodurans

Qin-Tian Qiu, Cai-Yun Zhang, Zhi-Peng Gao et al. Jan 01, 2025 pp. 108068 10.1016/j.jbc.2024.108068

The signaling landscape of insulin-like growth factor 1

Muhammad Zahid Khan, Jose Luis Zugaza, Ignacio Torres Aleman Jan 01, 2025 pp. 108047 10.1016/j.jbc.2024.108047

Dynamic O-GlcNAcylation coordinates etoposide-triggered tumor cell pyroptosis by regulating p53 stability

Jing Wang, Yida Wang, Huan Xiao et al. Jan 01, 2025 pp. 108050 10.1016/j.jbc.2024.108050

Thrombin confers chemotherapeutic resistance by promoting transcriptional induction and post-translational stabilization of pro-survival MCL1 in TNBC

Subhojit Paul, Akash Chatterjee, Kaushik Das et al. Jan 01, 2025 pp. 108025 10.1016/j.jbc.2024.108025

Structural basis for the pathogenicity of parkin catalytic domain mutants

Julian P. Wagner, Véronique Sauvé, Anshu Saran et al. Jan 01, 2025 pp. 108051 10.1016/j.jbc.2024.108051

A conserved acidic residue drives thyroxine synthesis within thyroglobulin and other protein precursors

Camilla Stejskalova, Federica Arrigoni, Riccardo Albanesi et al. Jan 01, 2025 pp. 108026 10.1016/j.jbc.2024.108026

Inhibition of the neddylation E2 enzyme UBE2M in macrophages protects against E. coli-induced sepsis

Xuehuan Wen, Songjie Bai, Guirun Xiong et al. Jan 01, 2025 pp. 108085 10.1016/j.jbc.2024.108085

Purification of micrococcal nuclease for use in ribosomal profiling of high-salinity extremophiles

Pavlina Gregorova, Matthew Isada, Jocelyne DiRuggiero et al. Jan 01, 2025 pp. 108020 10.1016/j.jbc.2024.108020

mRNA vaccine sequence and structure design and optimization: Advances and challenges

Lei Jin, Yuanzhe Zhou, Sicheng Zhang et al. Jan 01, 2025 pp. 108015 10.1016/j.jbc.2024.108015

Iron regulatory protein 1-deficient mice exhibit hypospermatogenesis

Aileen Harrer, Niraj Ghatpande, Tiziana Grimaldini et al. Jan 01, 2025 pp. 108067 10.1016/j.jbc.2024.108067

Dual-ligand fluorescence microscopy enables chronological and spatial histological assignment of distinct amyloid-β deposits

Therése Klingstedt, Hamid Shirani, Farjana Parvin et al. Jan 01, 2025 pp. 108032 10.1016/j.jbc.2024.108032

The structural basis for high-affinity c-di-GMP binding to the GSPII-B domain of the traffic ATPase PilF from Thermus thermophilus

Konstantin Neißner, Heiko Keller, Lennart Kirchner et al. Jan 01, 2025 pp. 108041 10.1016/j.jbc.2024.108041

The putative polyamine transporter Shp2 facilitates phosphate export in an Xpr1-independent manner and contributes to high phosphate tolerance

Tochi Komamura, Tomoki Nishimura, Naoki Ohta et al. Jan 01, 2025 pp. 108056 10.1016/j.jbc.2024.108056