Journal of Biological Chemistry

Cryo-EM structures reveal the PP2A–B55α and Eya3 interaction that can be disrupted by a peptide inhibitor

Shasha Shi, Xueni Li, Christopher Alderman et al. Jul 01, 2025 pp. 110287 10.1016/j.jbc.2025.110287

The human autophagy-initiating complexes ULK1C and PI3KC3-C1

Minghao Chen, James H. Hurley Jul 01, 2025 pp. 110391 10.1016/j.jbc.2025.110391

Written in chromatin: The enduring legacy of C. David Allis

Brian D. Strahl, Gang Greg Wang Jul 01, 2025 pp. 110240 10.1016/j.jbc.2025.110240

FAK activity exacerbates disturbed flow-mediated atherosclerosis via VEGFR2-CBL-NF-κB signaling

James M. Murphy, Duyen Thi Kieu Tran, Kyuho Jeong et al. Jul 01, 2025 pp. 110383 10.1016/j.jbc.2025.110383

5hmC enhances PARP trapping and restores PARP inhibitor sensitivity in chemoresistant BRCA1/2-deficient cells

Suhas S. Kharat, Arun P. Mishra, Satheesh K. Sengodan et al. Jul 01, 2025 pp. 110393 10.1016/j.jbc.2025.110393

Ancestral evolution of oxidase activity in a class of (S)-nicotine and (S)-6-hydroxynicotine-degrading flavoenzymes

Zhiyao Zhang, Parth R. Bandivadekar, Andrew J. Gaunt et al. Jul 01, 2025 pp. 110360 10.1016/j.jbc.2025.110360

Structural and functional insights into Listeria monocytogenes phage endolysin PlyP100: A promising food safety tool

Karson R. Bateman, Emma Scaletti Hutchinson, Göran Widmalm et al. Jul 01, 2025 pp. 110295 10.1016/j.jbc.2025.110295

ARRDC3 tyrosine phosphorylation functions as a switch to control c-Src versus WWP2 interactions and distinct scaffolding functions

Mika Caplan, Carolyne Bardeleben, Kanika Dhawan et al. Jul 01, 2025 pp. 110270 10.1016/j.jbc.2025.110270

Single-subunit RNA polymerases, KpnP, Ro45Iw, and CD23823, with precise terminal synthesis

Haruka Takatsuki, Ryota Miyachi, Kaito Seo et al. Jul 01, 2025 pp. 110359 10.1016/j.jbc.2025.110359

Machine learning–based multimodal radiomics and transcriptomics models for predicting radiotherapy sensitivity and prognosis in esophageal cancer

Chengyu Ye, Hao Zhang, Zhou Chi et al. Jul 01, 2025 pp. 110242 10.1016/j.jbc.2025.110242

Structural basis of cuproenzyme nitrite reduction at the level of a single hydrogen atom

Yohta Fukuda, Masami Lintuluoto, Yu Hirano et al. Jul 01, 2025 pp. 110290 10.1016/j.jbc.2025.110290

Estradiol (E2) concentration shapes the chromatin binding landscape of estrogen receptor alpha

Amy L. Han, Kiran Vinod Paul, Satyanarayan Rao et al. Jul 01, 2025 pp. 108499 10.1016/j.jbc.2025.108499

Rag GTPases control lysosomal acidification by regulating v-ATPase assembly in Drosophila

Ying Zhou, Xiaodie Yang, Wenyu Xu et al. Jul 01, 2025 pp. 110400 10.1016/j.jbc.2025.110400

BET bromodomain inhibitors attenuate transcription of a subset of IL-1-induced NF-κB targets that promote inflammation in β-cells

Joshua A. Nord, Savannah J. Makowski, Paul F.W. Sidlowski et al. Jul 01, 2025 pp. 110358 10.1016/j.jbc.2025.110358

Targeted removal of the 16S rRNA anti-Shine–Dalgarno sequence by a Mycobacterium tuberculosis MazF toxin

Timothy W. Sherrier, Valdir C. Barth, Jason M. Schifano et al. Jul 01, 2025 pp. 110323 10.1016/j.jbc.2025.110323

Retraction: Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling

Kenji Kasuno, Satoshi Takabuchi, Kazuhiko Fukuda et al. Jul 01, 2025 pp. 110219 10.1016/j.jbc.2025.110219

Perturbations in L-serine metabolism regulate protein quality control through the sensor of the retrograde response pathway RTG2 in Saccharomyces cerevisiae

Kanika Saxena, Rebecca Andersson, Per O. Widlund et al. Jul 01, 2025 pp. 110329 10.1016/j.jbc.2025.110329

CpgD is a phosphoglycerate cytidylyltransferase required for ceramide diphosphoglycerate synthesis

Tanisha Dhakephalkar, Ziqiang Guan, Eric A. Klein Jul 01, 2025 pp. 110386 10.1016/j.jbc.2025.110386

Mechanisms of USP18 specificity toward ISG15 revealed by paralog sequence analysis comparison

Thomas Bonacci, Derek L. Bolhuis, Nicholas G. Brown et al. Jul 01, 2025 pp. 110288 10.1016/j.jbc.2025.110288

Lysophospholipid stereoisomers exert distinct GPR55-mediated functions via different Gα subunits

Adam T. Guy, Yuta Kohro, Koki Kano et al. Jul 01, 2025 pp. 110324 10.1016/j.jbc.2025.110324

Crustacean methyl farnesoate–binding protein is an insect juvenile hormone–binding protein homolog that inhibits molting

Hao Yang, Ting Chen, Xin Zhang et al. Jul 01, 2025 pp. 110297 10.1016/j.jbc.2025.110297

Unique structural features define the decarboxylation activity of a CYP152 fatty acid decarboxylase from Lacicoccus alkaliphilus

Suppalak Phaisan, Aisaraphon Phintha, Duangthip Trisrivirat et al. Jul 01, 2025 pp. 110397 10.1016/j.jbc.2025.110397

Fast peptide bond formation and release by the ribosomal large subunit

Letian Bao, Anthony C. Forster Jul 01, 2025 pp. 110336 10.1016/j.jbc.2025.110336

Induction of the zinc finger transcription factor GATA2 promotes kidney inflammation-related gene expression

Jun Takai, Hinata Ueki, Satoshi Uemura Jul 01, 2025 pp. 110372 10.1016/j.jbc.2025.110372

Humanin variants aggregate to produce different fibril morphologies

Daniel L. Morris, Sarah B. Nyenhuis, James M. Gruschus et al. Jul 01, 2025 pp. 110403 10.1016/j.jbc.2025.110403