Journal of Biological Chemistry

CpX Hunter web tool allows high-throughput identification of CpG, CpA, CpT, and CpC islands: A case study in Drosophila genome

Martin Bartas, Michal Petrovič, Václav Brázda et al. Jun 01, 2025 pp. 108537 10.1016/j.jbc.2025.108537

Discovery and biochemical characterization of the D-aspartyl endopeptidase activity of the serine protease LACTB

Genta Ito, Naoko Utsunomiya-Tate Jun 01, 2025 pp. 108549 10.1016/j.jbc.2025.108549

Phosphorylation of SNX17 impedes activation of Retriever-mediated sorting

Jan Dominik Speidel, Kaikai Yu, Ralph Thomas Böttcher Jun 01, 2025 pp. 110222 10.1016/j.jbc.2025.110222

Altering the ligand specificity of DectiSomes

Suresh Ambati, Xiaorong Lin, Zachary A. Lewis et al. Jun 01, 2025 pp. 108566 10.1016/j.jbc.2025.108566

Characterization of a two-component kinase that initiates the bacterial catabolism of hydroxyphenylethanones

Gara N. Dexter, Jason C. Grigg, Michael Zahn et al. Jun 01, 2025 pp. 110210 10.1016/j.jbc.2025.110210

Crystal structure and mutagenesis of a nucleic acid–binding BRCT domain in human PARP4

Léonie Frigon, John M. Pascal Jun 01, 2025 pp. 110277 10.1016/j.jbc.2025.110277

In situ detection of activation of CAPN3, a responsible gene product for LGMDR1, in mouse skeletal myotubes

Chihiro Hisatsune, Fumiko Shinkai-Ouchi, Shoji Hata et al. Jun 01, 2025 pp. 108536 10.1016/j.jbc.2025.108536

Allosteric factors in the calcium/calmodulin-responsive kinase II hub domain determine selectivity of GHB ligands for CaMKIIα

Stine J. Gauger, Line B. Palmelund, Yongsong Tian et al. Jun 01, 2025 pp. 108543 10.1016/j.jbc.2025.108543

Biochemical impact of p300-mediated acetylation of replication protein A: Implications for DNA metabolic pathway choice

Onyekachi Ononye, Sneha Surendran, Tripthi Battapadi et al. Jun 01, 2025 pp. 110250 10.1016/j.jbc.2025.110250

Recently discovered heteromeric enzymes in natural product biosynthesis

Zhongtian Yu, Ikuro Abe Jun 01, 2025 pp. 108516 10.1016/j.jbc.2025.108516

The nucleocapsid protein of Crimean–Congo hemorrhagic fever virus interacts with eIF4A to promote the translation of viral mRNA in cells

Saima Ali, Songyang Ren, Alexis Agsaoa et al. Jun 01, 2025 pp. 110173 10.1016/j.jbc.2025.110173

DNA stimulates the deacetylase SIRT6 to mono-ADP-ribosylate proteins with histidine repeats

Nicholas J. Pederson, Katharine L. Diehl Jun 01, 2025 pp. 108532 10.1016/j.jbc.2025.108532

Optimization of the PROTAC linker region of the proteasome substrate receptor hRpn13 rationalized by structural modeling with molecular dynamics

Xiuxiu Lu, Venkata R. Sabbasani, Bakar Hassan et al. Jun 01, 2025 pp. 108520 10.1016/j.jbc.2025.108520

Elevated mevalonolactone from Ruminococcus torques contributes to metabolically unhealthy obesity development

Hong-Yu Nie, Meng-Fei Zhao, Tian-Yu Wu et al. Jun 01, 2025 pp. 110281 10.1016/j.jbc.2025.110281

SART1 uniquely localizes to spindle poles forming a SART1 cap and promotes spindle pole assembly

Hideki Yokoyama, Daniel Moreno-Andrés, Kaoru Takizawa et al. Jun 01, 2025 pp. 108561 10.1016/j.jbc.2025.108561

Potent activity of prostaglandin J2 on prostanoid DP receptors

Kanaho Senoo, Keijo Fukushima, Hitomi Yamamoto et al. Jun 01, 2025 pp. 108523 10.1016/j.jbc.2025.108523

UCHL1 regulates adiponectin receptors in Sertoli cells to maintain testicular homeostatic balance

Donghui Yang, Wenbo Chen, Ning Zhang et al. Jun 01, 2025 pp. 110221 10.1016/j.jbc.2025.110221

ABHD18 degrades cardiolipin by stepwise hydrolysis of fatty acids

Mindong Ren, Shiyu Chen, Miriam L. Greenberg et al. Jun 01, 2025 pp. 110237 10.1016/j.jbc.2025.110237

Endocytosis of sialic acid Neu5Gc and elevated p53 contributes to preimplantation embryonic arrest during in vitro fertilization

Xin Yuan, Yilun Wu, Yi Zhang et al. Jun 01, 2025 pp. 110254 10.1016/j.jbc.2025.110254

Microbial metabolite ammonia disrupts TGF-β signaling to promote colon cancer

Krishanu Bhowmick, Xiaochun Yang, Taj Mohammad et al. Jun 01, 2025 pp. 108559 10.1016/j.jbc.2025.108559

Structure and catalytic mechanism of methylisocitrate lyase, a potential drug target against Coxiella burnetii

William S. Stuart, Christopher H. Jenkins, Philip M. Ireland et al. Jun 01, 2025 pp. 108517 10.1016/j.jbc.2025.108517

Impact of an oxidative RNA lesion on in vitro replication catalyzed by SARS-CoV-2 RNA-dependent RNA polymerase

Masataka Akagawa, Kaoru Sugasawa, Kiyoe Ura et al. Jun 01, 2025 pp. 108512 10.1016/j.jbc.2025.108512

Damage-associated molecular patterns (DAMPs) in vascular diseases

Jacob Antonello, Partha Roy Jun 01, 2025 pp. 110241 10.1016/j.jbc.2025.110241

Constitutively active Arabidopsis cryptochrome 2 alleles identified using yeast selection and deep mutational scanning

Amir Taslimi, Axel Jeibmann, Lukas Goett-Zink et al. Jun 01, 2025 pp. 110265 10.1016/j.jbc.2025.110265

The impact of subunit type, alternative splicing, and auxiliary proteins on AMPA receptor trafficking

Tyler Couch, Tyler W. McCullock, David M. MacLean Jun 01, 2025 pp. 108569 10.1016/j.jbc.2025.108569