Journal of Biological Chemistry

The deacetylase NagA mediates the remodeling and recycling of peptidoglycan-derived amino sugars in mycobacteria

Collette S. Guy, Charlotte Cooper, Magdalena Karlikowska et al. Nov 01, 2025 pp. 110597 10.1016/j.jbc.2025.110597

Transmembrane domain interactions underlie NSG1 regulation of sortilin ectodomain shedding

Malene Overby, Lasse Messell Desdorf, Lisbeth Kjølbye et al. Nov 01, 2025 pp. 110804 10.1016/j.jbc.2025.110804

Death, taxes, and rhomboids: Understanding the ubiquitous roles of the rhomboid protein superfamily

Henry Sawczyc, Spyridon Kosteletos, Adam Lange Nov 01, 2025 pp. 110699 10.1016/j.jbc.2025.110699

Widespread deployment of the human CD38 ADP-ribosyl cyclase fold in antibacterial and anti-eukaryotic polymorphic toxins

Julius Martinkus, Laurent Terradot, Dukas Jurėnas et al. Nov 01, 2025 pp. 110775 10.1016/j.jbc.2025.110775

A farnesoid X receptor T296I variant disrupts ligand-induced FXR activation and thus bile acid transport in progressive familial intrahepatic cholestasis

Annika Behrendt, Alex Bastianelli, Jan Stindt et al. Nov 01, 2025 pp. 110769 10.1016/j.jbc.2025.110769

Creatine kinase B promotes non–small cell lung cancer survival and metastasis

Mouna Tlili, Bozena Samborska, Charlotte Girondel et al. Nov 01, 2025 pp. 110805 10.1016/j.jbc.2025.110805

The nonconserved integrin cytoplasmic region determines integrin subtype–specific characteristics by modulating talin1 binding kinetics

Naoyuki Kondo, Kenji Fukui, Yuji Kamioka et al. Nov 01, 2025 pp. 110793 10.1016/j.jbc.2025.110793

SAG1.3-derived Frizzled-targeting small-molecule compounds

Lukas Grätz, Ainoleena Turku, Pawel Kozielewicz et al. Nov 01, 2025 pp. 110751 10.1016/j.jbc.2025.110751

A short SUMOylation tag modulates transcription factor activity

Antoine Y. Bouchard, Anaïs J.I. Vivet, Valérie C. Cabana et al. Nov 01, 2025 pp. 110807 10.1016/j.jbc.2025.110807

The cytoplasmic domains of the CNNM family of transmembrane proteins modulate the ion channel-kinase TRPM7

Sandra Tetteh, Pengyu Zong, Jianlin Feng et al. Nov 01, 2025 pp. 110720 10.1016/j.jbc.2025.110720

The deubiquitinase OTUD4 suppresses TAK1 kinase–dependent NF-κB signaling and inflammation

Zhaohui Liu, Xiaolong Wang, Lihui Wu et al. Nov 01, 2025 pp. 110784 10.1016/j.jbc.2025.110784

Structural insights into hormone recognition and G-protein coupling of the urotensin-II receptor

Tianyu Gao, Chongzhao You, Yinglong Cao et al. Nov 01, 2025 pp. 110794 10.1016/j.jbc.2025.110794

Systematic analysis of the RGS2 degron reveals characteristics of substrate recognition by the F-box protein FBXO44

Harrison J. McNabb, Eugene Cho, Mary Pitman et al. Nov 01, 2025 pp. 110757 10.1016/j.jbc.2025.110757

Human sperm KSper is physiologically activated by intracellular pH alkalization and CatSper-mediated Ca2+ signaling

Hang Kang, Huafeng Wang, Jie Wu et al. Nov 01, 2025 pp. 110752 10.1016/j.jbc.2025.110752

Ascorbate mitigates oxidative stress and hemin cytotoxicity in heme oxygenase-1 deficiency

Lea-Sophie Berendes, Petra Schulze Westhoff, Ann-Marie Tobinski et al. Nov 01, 2025 pp. 110705 10.1016/j.jbc.2025.110705

Compartmentalized thymidine phosphorylation by mitochondrial nucleotide kinases TK2 and CMPK2

Avery S. Ward, Vasudeva G. Kamath, Chia-Heng Hsiung et al. Nov 01, 2025 pp. 110733 10.1016/j.jbc.2025.110733

Filamentous structure of the CotVW complex, the crust proteins of the Bacillus subtilis endospore

Eunbyul Jo, Doyeon Kim, Yeongjin Baek et al. Nov 01, 2025 pp. 110714 10.1016/j.jbc.2025.110714

Microphysiological systems as a pillar of the Human Exposome Project

Fenna C.M. Sillé, Lena Smirnova, Thomas Hartung Nov 01, 2025 pp. 110782 10.1016/j.jbc.2025.110782

The ubiquitin-binding protein ANKRD13A mediates VCP-dependent mitochondrial outer membrane rupture during PINK1/Parkin-mediated mitophagy

Wei-Hua Chu, Yu-Shan Lin, Jing Guo et al. Nov 01, 2025 pp. 110739 10.1016/j.jbc.2025.110739

S2Tag, a novel affinity tag for the capture and immobilization of coiled-coil proteins: Application to the study of human β-cardiac myosin

Bipasha Barua, Robert C. Cail, Yale E. Goldman et al. Nov 01, 2025 pp. 110776 10.1016/j.jbc.2025.110776

NITAC-mediated ISGylation of eIF4E2 attenuates GSK3β proline-directed kinase activity, conferring cytoprotection

Lan Li, Jinjin Gong, Huiting Liang et al. Nov 01, 2025 pp. 110777 10.1016/j.jbc.2025.110777

Biochemical reconstitution of temozolomide-induced mutational processes

Mahima R. Sanyal, Tomohiko Sugiyama Nov 01, 2025 pp. 110676 10.1016/j.jbc.2025.110676

Nitric oxide regulates phagocytosis through S-nitrosylation of Rab5

Makoto Hagiwara, Hiroyuki Tada, Kenji Matsushita Nov 01, 2025 pp. 110696 10.1016/j.jbc.2025.110696

The growth factor FGF21 maintains neuromuscular junction through histone deacetylase HDAC4 in denervation-induced skeletal muscle atrophy

Lirong Zheng, Takashi Sasaki, Liyang Ni et al. Nov 01, 2025 pp. 110756 10.1016/j.jbc.2025.110756

Correction: Molecular basis of acyl-CoA ester recognition by α-methylacyl-CoA racemase from Mycobacterium tuberculosis

Otsile O. Mojanaga, Timothy J. Woodman, Matthew D. Lloyd et al. Nov 01, 2025 pp. 110790 10.1016/j.jbc.2025.110790