Journal of Biological Chemistry

Kinetics insight into the roles of the N- and C-lobes of calmodulin in RyR1 channel regulation

Jingyan Zhang, Levy M. Treinen, Skylar J. Mast et al. Mar 01, 2025 pp. 108258 10.1016/j.jbc.2025.108258

Differential producibility analysis reveals drug-associated carbon and nitrogen metabolite expressions in Mycobacterium tuberculosis

Ye Xu, Ruma Banerjee, Sunitha Kasibhatla et al. Mar 01, 2025 pp. 108288 10.1016/j.jbc.2025.108288

Modulation of the substrate preference of a MYST acetyltransferase by a scaffold protein

Raghuvir N. Sengupta, Oleg Brodsky, Patrick Bingham et al. Mar 01, 2025 pp. 108262 10.1016/j.jbc.2025.108262

The glycoprotein GPNMB protects against oxidative stress through enhanced PI3K/AKT signaling in epidermal keratinocytes

Natsuki Nishida, Mariko Otsu, Yukiko Mizutani et al. Mar 01, 2025 pp. 108299 10.1016/j.jbc.2025.108299

Topology-driven discovery of transmembrane protein S-palmitoylation

Michael T. Forrester, Jacob R. Egol, Sinan Ozbay et al. Mar 01, 2025 pp. 108259 10.1016/j.jbc.2025.108259

O-GlcNAc modification differentially regulates microtubule binding and pathological conformations of tau isoforms in vitro

Mohammed M. Alhadidy, Paul M. Stemmer, Nicholas M. Kanaan Mar 01, 2025 pp. 108263 10.1016/j.jbc.2025.108263

Sulfoglycolysis sustains Eubacterium rectale in low-fiber diets

Mahima Sharma, Nicholas Pudlo, Michael A. Järvå et al. Mar 01, 2025 pp. 108320 10.1016/j.jbc.2025.108320

Structure of a mutated photosystem II complex reveals changes to the hydrogen-bonding network that affect proton egress during O–O bond formation

David A. Flesher, Jieun Shin, Richard J. Debus et al. Mar 01, 2025 pp. 108272 10.1016/j.jbc.2025.108272

Combined deletion of cytosolic 5′-nucleotidases IA and II lowers glycemia by improving skeletal muscle insulin action and lowering hepatic glucose production

Roxane Jacobs, Gaëtan Herinckx, Noémie Galland et al. Mar 01, 2025 pp. 108295 10.1016/j.jbc.2025.108295

Spider-derived peptide LCTx-F2 suppresses ASIC channels by occupying the acidic pocket

Canwei Du, Fuchu Yuan, Zhongzhe Zhang et al. Mar 01, 2025 pp. 108286 10.1016/j.jbc.2025.108286

FXR-ApoC2 pathway activates UCP1-mediated thermogenesis by promoting the browning of white adipose tissues

Sang Hee Kim, Woo Yong Park, Beomsu Kim et al. Mar 01, 2025 pp. 108181 10.1016/j.jbc.2025.108181

Molecular sorting of nitrogenase catalytic cofactors

Alvaro Salinero-Lanzarote, Josh Lian, Gil Namkoong et al. Mar 01, 2025 pp. 108291 10.1016/j.jbc.2025.108291

Extremophilic hemoglobins: The structure of Shewanella benthica truncated hemoglobin N

Jaime E. Martinez Grundman, Thomas D. Schultz, Jamie L. Schlessman et al. Mar 01, 2025 pp. 108223 10.1016/j.jbc.2025.108223

Recombinant antibodies inhibit enzymatic activity of the E3 ubiquitin ligase CHIP via multiple mechanisms

Dong hee Chung, Emily J. Connelly, Aparna Unnikrishnan et al. Mar 01, 2025 pp. 108220 10.1016/j.jbc.2025.108220

Blocking activation of the C1r zymogen defines a novel mode of complement inhibition

Huiquan Duan, Wei Wu, Ping Li et al. Mar 01, 2025 pp. 108301 10.1016/j.jbc.2025.108301

Aquaporin five deficiency suppresses fatty acid oxidation and delays liver regeneration through the transcription factor PPAR

Bin Li, Shixu Liu, Wenshuo Han et al. Mar 01, 2025 pp. 108303 10.1016/j.jbc.2025.108303

Transmembrane Parkinson’s disease mutation of PINK1 leads to altered mitochondrial anchoring

Raelynn Brassard, Elena Arutyunova, Emmanuella Takyi et al. Mar 01, 2025 pp. 108253 10.1016/j.jbc.2025.108253

A novel FOXM1–BCL2A1 axis determines unfavorable response to venetoclax in AML

Sanjeev Raghuwanshi, Ahmed Magdy, Nissim Hay et al. Mar 01, 2025 pp. 108240 10.1016/j.jbc.2025.108240

Enhanced kinase translocation reporters for simultaneous real-time measurement of PKA, ERK, and calcium

Shang-Jui Tsai, Yijing Gong, Austin Dabbs et al. Mar 01, 2025 pp. 108183 10.1016/j.jbc.2025.108183

Correction: Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression

Dandan Wang, Xiaoxiao Yang, Yuanli Chen et al. Mar 01, 2025 pp. 108269 10.1016/j.jbc.2025.108269

Aggregated proinsulin in pancreatic β-cells is degraded by the autophagy pathway

Yueh-Fu Madey, Samreen K. Syed, Robert Daniel Van Horn et al. Mar 01, 2025 pp. 108257 10.1016/j.jbc.2025.108257

The yeast checkpoint kinase Dun1p represses transcription of RNR genes independently of catalytic activity or Rad53p during respiratory growth

Shreya Nagar, Riddhi Mehta, Pritpal Kaur et al. Mar 01, 2025 pp. 108232 10.1016/j.jbc.2025.108232

MIA40 circumvents the folding constraints imposed by TRIAP1 function

Jordi Pujols, Marc Fornt-Suñé, Marcos Gil-García et al. Mar 01, 2025 pp. 108268 10.1016/j.jbc.2025.108268

Auranofin induces disulfide bond–mimicking S-Au adducts in protein thiol pairs

Laísa Quadros Barsé, Petra Düchting, Natalie Lupilov et al. Mar 01, 2025 pp. 108159 10.1016/j.jbc.2025.108159

Stabilized designs of the malaria adhesin protein PvRBP2b for use as a potential diagnostic for Plasmodium vivax

Jaison D Sa, Lucas Krauss, Lauren Smith et al. Mar 01, 2025 pp. 108290 10.1016/j.jbc.2025.108290