Journal of Biological Chemistry

Ago1 is required for the regulation of mitochondrial translation under heat stress in Schizosaccharomyces pombe

Mengling Yu, Yuanqi Xu, Yijing Lu et al. Jul 01, 2026 pp. 113235 10.1016/j.jbc.2026.113235

Tail-anchored protein C-terminal domains stimulate ATP hydrolysis by the P5A-ATPase Spf1p

Elio O. Cianci, Luciana R. Mazzitelli, Hugo P. Adamo Jul 01, 2026 pp. 113205 10.1016/j.jbc.2026.113205

An ART-fold Rhs toxin from Pluralibacter gergoviae defines Tne5, a novel family of NAD(P) glycohydrolases effectors

Jonas B. Desjardins, Martin Durrmeyer, Olivier Bornet et al. Jul 01, 2026 pp. 113182 10.1016/j.jbc.2026.113182

EsxA is required for antibacterial toxin export by the type VIIb secretion system

Prakhar Y. Shah, Stephen R. Garrett, Timothy A. Klein et al. Jul 01, 2026 pp. 113240 10.1016/j.jbc.2026.113240

Cell type-specific expression and subcellular localization of the human insulin upstream open reading frame (INSU) protein in pancreatic β-cells

Qing-Rong Liu, Min Zhu, Lisa M. Hartnell et al. Jul 01, 2026 pp. 113209 10.1016/j.jbc.2026.113209

Hydrogen-deuterium exchange points to inter-domain interactions in reverse gyrase that modulate conformational changes in positive DNA supercoiling

Vaibhav P. Mhaindarkar, Frederic Collin, Philipp Koldewey et al. Jul 01, 2026 pp. 113233 10.1016/j.jbc.2026.113233

Alpha-cell glucagon is essential for maintaining β-cell function and identity in adult mice

Krishna Prasadan, Mohamed Saleh, Madison Thomas et al. Jul 01, 2026 pp. 113145 10.1016/j.jbc.2026.113145

Differential ErbB receptor dimerization modulates the ability of EGF receptor ligands to regulate metabolic flux

Jennifer Macdonald-Obermann, Kevin Cho, Gary J. Patti et al. Jul 01, 2026 pp. 113230 10.1016/j.jbc.2026.113230

Ginkgolide A enhances cardiomyocyte differentiation from pluripotent stem cells by targeting cytochrome c to attenuate intrinsic apoptosis

Wenjie Xu, Xiaolong Wu, Zuo Lei et al. Jul 01, 2026 pp. 113224 10.1016/j.jbc.2026.113224

Structural basis for selective thymidine binding by the Borrelia burgdorferi substrate-binding protein BmpA

Qianqiao Liu, Victor A. Nuñez, Daniel Fernandez et al. Jul 01, 2026 pp. 113206 10.1016/j.jbc.2026.113206

LeGenD: High-throughput N-glycan profiling using explainable AI and lectin profiling

Haining Li, Angelo G. Peralta, Sanne Schoffelen et al. Jul 01, 2026 pp. 113234 10.1016/j.jbc.2026.113234

LATS kinase activity and tumor suppressor function are regulated by a second autophosphorylation site

Ruxin Jin, Zhenxing Zhong, Rui Zhu et al. Jul 01, 2026 pp. 113177 10.1016/j.jbc.2026.113177

SARS-CoV-2 5′-UTR stem-loops activate the antiviral protein oligoadenylate synthetase 1 (OAS1)

Alejandro Oviedo, Camden R. Bair, Alexander P. Vasilakopoulos et al. Jul 01, 2026 pp. 113194 10.1016/j.jbc.2026.113194

Control of the committed step in lipopolysaccharide biosynthesis

Wei Mi, Rajkanwar Nathawat, Hongpeng Wang et al. Jul 01, 2026 pp. 113238 10.1016/j.jbc.2026.113238

LRRC71 is essential for sperm motility, fertilization, and male fertility

Lu Yuan, Chuan Xu, Tingting Ge et al. Jul 01, 2026 pp. 113176 10.1016/j.jbc.2026.113176

GRP75 chaperone-driven mitochondria–ER membrane coupling promotes Ca2+-dependent ROS accumulation and ferroptosis during hypoxic stress

Haoxiao Yan, Penggeng Chen, Yaoyi Zhang et al. Jul 01, 2026 pp. 113215 10.1016/j.jbc.2026.113215

Starvation-induced HSC70 O-GlcNAcylation activates chaperone-mediated autophagy

Ningda Xu, Xiangpeng Wang, Jiyue Zhang et al. Jul 01, 2026 pp. 113165 10.1016/j.jbc.2026.113165

microRNAs bidirectionally regulate FUT1 to modulate α-1,2-fucosylation and cancer-associated biology

Tigist Batu, Chu Thu, Lara K. Mahal Jul 01, 2026 pp. 113217 10.1016/j.jbc.2026.113217

Deciphering resistance mechanisms to auxin-inducible protein degradation in mammalian cells

Judith Hyle, Zhenling Liu, Shaela Fields et al. Jul 01, 2026 pp. 113232 10.1016/j.jbc.2026.113232

The carbohydrate-binding module of TrCel7A aids in navigating hemicellulose barriers in plant cell walls

Nerya Zexer, Alec Paradiso, Anuleka Dutta et al. Jul 01, 2026 pp. 113218 10.1016/j.jbc.2026.113218

HuR-HuB autoregulatory network governs inflammatory factors expression

Xingyue Fu, Yuhan Lu, Leying Kong et al. Jul 01, 2026 pp. 113175 10.1016/j.jbc.2026.113175

Stable maintenance of MERVL-positive embryonic stem cells reveals sustained transcriptional programs and enhancer remodeling

Rui Geng, Benjamin L. Kidder Jul 01, 2026 pp. 113166 10.1016/j.jbc.2026.113166

Higher-order structural organization of mitochondrial metabolism

Greg Kafetzopoulos, Jonas Döbler, Panagiotis L. Kastritis Jul 01, 2026 pp. 113174 10.1016/j.jbc.2026.113174

The multiple sclerosis drug fingolimod induces pore-like membrane defects, contributing to its antimicrobial activity

Antara Syam, Benjamin Rees, Sebastian Cuervo et al. Jul 01, 2026 pp. 113164 10.1016/j.jbc.2026.113164

Lactate-fueled H3K18 lactylation sustains ΔNp63α-dependent self-renewal in limbal epithelial stem cells

Longfei Li, Lin Zhu, Liyuan Wang et al. Jul 01, 2026 pp. 113207 10.1016/j.jbc.2026.113207