Journal of Biological Chemistry

Elucidating ligand interactions and small-molecule activation in the pyrrolnitrin biosynthetic enzyme PrnB

Bingnan Li, Remigio Usai, Jackson Campbell et al. Feb 01, 2025 pp. 108123 10.1016/j.jbc.2024.108123

PTEN loss in glioma cell lines leads to increased extracellular vesicle biogenesis and PD-L1 cargo in a PI3K-dependent manner

Julio C. Sanchez, Timothy M. Pierpont, Dariana Argueta-Zamora et al. Feb 01, 2025 pp. 108143 10.1016/j.jbc.2024.108143

Mutations in histones dysregulate copper homeostasis leading to defect in Sec61-dependent protein translocation mechanism in Saccharomyces cerevisiae

Santoshi Acharjee, Rajshree Pal, Smriti Anand et al. Feb 01, 2025 pp. 108163 10.1016/j.jbc.2025.108163

Enhanced dynamic coupling in a nuclear receptor underlies ligand activity

Tracy Yu, Priscilla Villalona, Sabab Hasan Khan et al. Feb 01, 2025 pp. 108081 10.1016/j.jbc.2024.108081

mTOR signaling controls protein aggregation during heat stress and cellular aging in a translation- and Hsf1-independent manner

Arthur Fischbach, Per O. Widlund, Xinxin Hao et al. Feb 01, 2025 pp. 108172 10.1016/j.jbc.2025.108172

Histone N-tails modulate sequence-specific positioning of nucleosomes

Tatiana Nikitina, Wilfried M. Guiblet, Feng Cui et al. Feb 01, 2025 pp. 108138 10.1016/j.jbc.2024.108138

Discovery of a tribenzophenazine analog for binding to the KRAS mRNA G-quadruplex structures in the cisplatin-resistant non–small cell lung cancer

Xiao-Dong Wang, Jia-Hong Lin, Ming-Hao Hu Feb 01, 2025 pp. 108164 10.1016/j.jbc.2025.108164

Human microRNA miR-197-3p positively regulates HIV-1 virion infectivity through its target DDX52 by stabilizing Vif protein expression

Anindita Dasgupta, Anjali Tripathi, Alapani Mitra et al. Feb 01, 2025 pp. 108198 10.1016/j.jbc.2025.108198

Interplay of chromatin remodeling BAF complexes in mouse embryonic and epiblast stem cell conversion and maintenance

Zhaoru Ma, Shuping Tan, Renhong Lu et al. Feb 01, 2025 pp. 108140 10.1016/j.jbc.2024.108140

SETD7 promotes LC3B methylation and degradation in ovarian cancer

Ziwei Zhang, Mingyang Li, Yanan Hou et al. Feb 01, 2025 pp. 108134 10.1016/j.jbc.2024.108134

Interaction of unphosphorylated PtsN with the K+/H+ antiporter YcgO inhibits its activity in Escherichia coli

Yogesh Patidar, Arunabh Athreya, Ravish Sharma et al. Feb 01, 2025 pp. 108153 10.1016/j.jbc.2024.108153

Cabozantinib selectively induces proteasomal degradation of p53 somatic mutant Y220C and impedes tumor growth

Fang Lin Lv, Lu Zhang, Cheng Ji et al. Feb 01, 2025 pp. 108167 10.1016/j.jbc.2025.108167

Angiogenesis-promoting effect of SKP-SC-EVs-derived miRNA-30a-5p in peripheral nerve regeneration by targeting LIF and ANGPT2

Mi Shen, Xinli Ye, Qiang Zhou et al. Feb 01, 2025 pp. 108146 10.1016/j.jbc.2024.108146

Liver fatty acid binding protein FABP1 transfers substrates to cytochrome P450 4A11 for catalysis

Kevin D. McCarty, F. Peter Guengerich Feb 01, 2025 pp. 108168 10.1016/j.jbc.2025.108168

Analysis of eIF4E-family members in fungi contributes to their classification in eukaryotes

Greco Hernández, Daniela Ross-Kaschitza, Gabriel Moreno-Hagelsieb et al. Feb 01, 2025 pp. 108129 10.1016/j.jbc.2024.108129

Correction: Characterization of a cytochrome P450 that catalyzes the O-demethylation of lignin-derived benzoates

Megan E. Wolf, Daniel J. Hinchen, John E. McGeehan et al. Feb 01, 2025 pp. 108212 10.1016/j.jbc.2025.108212

Maternal obesity alters histone modifications mediated by the interaction between EZH2 and AMPK, impairing neural differentiation in the developing embryonic brain cortex

Thilina T. Alawathugoda, Muhammad Abid Sheikh, Anil Kumar Challagandla et al. Feb 01, 2025 pp. 108173 10.1016/j.jbc.2025.108173

Pancreatic expression of CPT1A is essential for whole body glucose homeostasis by supporting glucose-stimulated insulin secretion

Maggie P. Ducote, Caroline R. Cothern, Heidi M. Batdorf et al. Feb 01, 2025 pp. 108187 10.1016/j.jbc.2025.108187

Missense mutations of the ephrin receptor EPHA1 associated with Alzheimer’s disease disrupt receptor signaling functions

Mike Matsumoto, Maricel Gomez-Soler, Sara Lombardi et al. Feb 01, 2025 pp. 108099 10.1016/j.jbc.2024.108099

Unveiling ADAMTS12: A key driver of bladder cancer progression via COL3A1-Mediated activation of the FAK/PI3K/AKT signaling pathway

Jian-hua Xiao, Li-zhe Xu, Jin-zhuo Ning et al. Feb 01, 2025 pp. 108155 10.1016/j.jbc.2025.108155

The C-terminal α-helix is crucial for the activity of the bacterial ABC transporter BmrA

Veronika Osten, Kristin Oepen, Dirk Schneider Feb 01, 2025 pp. 108098 10.1016/j.jbc.2024.108098

New insights in uranium bioremediation by cytochromes of the bacterium Geotalea uraniireducens

Alexandre Almeida, David L. Turner, Marta A. Silva et al. Feb 01, 2025 pp. 108090 10.1016/j.jbc.2024.108090

Autophagy-related 7 (ATG7) regulates food intake and liver health during asparaginase exposure

Brian A. Zalma, Maria Ibrahim, Flavio C. Rodriguez-Polanco et al. Feb 01, 2025 pp. 108171 10.1016/j.jbc.2025.108171

Specific recognition mechanism of an antibody to sulfated tyrosine and its potential use in biological research

Kan Ujiie, Makoto Nakakido, Seisho Kinoshita et al. Feb 01, 2025 pp. 108176 10.1016/j.jbc.2025.108176

Axin-binding domain of glycogen synthase kinase 3β facilitates functional interactions with voltage-gated Na+ channel Nav1.6

Timothy John Baumgartner, Nolan Michael Dvorak, Nana Aboadwe Goode et al. Feb 01, 2025 pp. 108162 10.1016/j.jbc.2025.108162