Journal of Biological Chemistry

Covalent inhibition of the SARS-CoV-2 NiRAN domain via an active-site cysteine

Genaro Hernandez, Adam Osinski, Abir Majumdar et al. Apr 01, 2025 pp. 108378 10.1016/j.jbc.2025.108378

The glycolytic enzyme PKM2 regulates inflammatory osteoclastogenesis by modulating STAT3 phosphorylation

Mingjuan Li, Feng Li, Chongjie Zhu et al. Apr 01, 2025 pp. 108389 10.1016/j.jbc.2025.108389

A novel spider toxin as a selective antagonist of the Kv1 subfamily of voltage-gated potassium channels through gating modulation

Zhen Xiao, Xia You, Minzhi Chen et al. Apr 01, 2025 pp. 108341 10.1016/j.jbc.2025.108341

YibN, a bona fide interactor of the bacterial YidC insertase with effects on membrane protein insertion and membrane lipid production

Zhiyu Zhao, Nachi Yamamoto, John W. Young et al. Apr 01, 2025 pp. 108395 10.1016/j.jbc.2025.108395

Interaction between CaV2.1 and Junctophilin3/4 depends on the II-III loop of CaV2.1 and on the α-helical region of Junctophilin3/4

Stefano Perni, Alexander Polster, Kurt G. Beam Apr 01, 2025 pp. 108424 10.1016/j.jbc.2025.108424

Substrate-specific effects point to the important role of Y361 as part of the YER motif in closing the binding pocket of OCT1

Sarah Römer, Erika Lazzarin, Anna Neumann et al. Apr 01, 2025 pp. 108318 10.1016/j.jbc.2025.108318

Pseudomonas aeruginosa PfpI is a methylglyoxalase

Larson Grimm, Andre Wijaya, Isabel Askenasy et al. Apr 01, 2025 pp. 108374 10.1016/j.jbc.2025.108374

Mitochondrial glutaredoxin Grx5 functions as a central hub for cellular iron-sulfur cluster assembly

Ashutosh K. Pandey, Jayashree Pain, Pratibha Singh et al. Apr 01, 2025 pp. 108391 10.1016/j.jbc.2025.108391

Double prenylation of budding yeast Ykt6 regulates cell wall integrity and autophagy

Masaki Tateishi, Kota Goto, Eiji Hishinuma et al. Apr 01, 2025 pp. 108384 10.1016/j.jbc.2025.108384

Substrate recognition and cleavage-site preferences of Lon protease

Melanie Cragan, Neha Puri, A. Wali Karzai Apr 01, 2025 pp. 108365 10.1016/j.jbc.2025.108365

ST3GAL1 regulates cancer cell migration through crosstalk between EGFR and neuropilin-1 signaling

Tan-chi Fan, Hui Ling Yeo, Tsai-Hsien Hung et al. Apr 01, 2025 pp. 108368 10.1016/j.jbc.2025.108368

Utility of binding protein fusions to immunoglobulin heavy chain constant regions from mammalian and avian species

Ningyu Zhu, Philip M. Smallwood, John Williams et al. Apr 01, 2025 pp. 108324 10.1016/j.jbc.2025.108324

Carbohydrate deacetylase, a key enzyme in oxidative chitin degradation, is evolutionarily linked to amino acid deacetylase

Jing-Ping Wang, Xiang-Ming Zhao, Xiao-Lei Liu et al. Apr 01, 2025 pp. 108420 10.1016/j.jbc.2025.108420

Differential association of EphA2 intracellular regions in biased signaling

Elmer Zapata-Mercado, Randall R. Rainwater, Ece Özdemir et al. Apr 01, 2025 pp. 108383 10.1016/j.jbc.2025.108383

Structural and functional characterization of the extended-diKH domain from the antiviral endoribonuclease KHNYN

Rebecca L. Youle, María José Lista, Clement Bouton et al. Apr 01, 2025 pp. 108336 10.1016/j.jbc.2025.108336

Polarization-independent regulation of the subcellular localization of Yes-associated protein 1 during preimplantation development

Shun Saito, Koji Nishiyama, Hanako Bai et al. Apr 01, 2025 pp. 108429 10.1016/j.jbc.2025.108429

Androgen receptor–induced lncRNA SOX2-OT promotes triple-negative breast cancer tumorigenesis via targeting miR-320a-5p–CCR5 axis

Yixuan Hu, Jin Bian, Weiwei Chen et al. Apr 01, 2025 pp. 108428 10.1016/j.jbc.2025.108428

The contribution of the Golgi and the endoplasmic reticulum to calcium and pH homeostasis in Toxoplasma gondii

Abigail Calixto, Katherine E. Moen, Silvia N.J. Moreno Apr 01, 2025 pp. 108372 10.1016/j.jbc.2025.108372

Spiroplasma eriocheiris FtsZ assembles the ring-like structure assisted by SepF

Taishi Kasai, Yuhei O. Tahara, Makoto Miyata et al. Apr 01, 2025 pp. 108373 10.1016/j.jbc.2025.108373

Spermine attenuates TGF-β-induced EMT by downregulating fibronectin

Huidong Liu, Ye-Guang Chen Apr 01, 2025 pp. 108352 10.1016/j.jbc.2025.108352

The structural basis of substrate selectivity of the acinetobactin biosynthetic adenylation domain, BasE

Syed Fardin Ahmed, Andrew M. Gulick Apr 01, 2025 pp. 108413 10.1016/j.jbc.2025.108413

Glutamate decarboxylase confers acid tolerance and enhances survival of mycobacteria within macrophages

Rupal Rai, Bijina J. Mathew, Rashmi Chourasia et al. Apr 01, 2025 pp. 108338 10.1016/j.jbc.2025.108338

In vitro characterization of the yeast DEAH/RHA RNA helicase Dhr1

Ran Lin, Ezzeddine Elmir, Madison J. Reynolds et al. Apr 01, 2025 pp. 108366 10.1016/j.jbc.2025.108366

BANCR-containing extracellular vesicles enhance breast cancer resistance

Xinming Song, Shen Liu, Ying Zeng et al. Apr 01, 2025 pp. 108304 10.1016/j.jbc.2025.108304

Direct observation of importin α family member KPNA1 in axonal transport with or without a schizophrenia-related mutation

Katsutoshi Mizuno, Masaki Sugahara, Osamu Kutomi et al. Apr 01, 2025 pp. 108343 10.1016/j.jbc.2025.108343