Journal of Biological Chemistry

A bacterial actin with high ATPase activity regulates the polymerization of a partner MreB isoform essential for Spiroplasma swimming motility

Daichi Takahashi, Hana Kiyama, Hideaki T. Matsubayashi et al. Aug 01, 2025 pp. 110462 10.1016/j.jbc.2025.110462

Myeloid loss of scaffolding protein menin promotes liver fibrosis via H3K36me3 reprogramming

Qing Han, Yujun Chen, Junbo Yuan et al. Aug 01, 2025 pp. 110471 10.1016/j.jbc.2025.110471

Copper acquisition in Bacillus subtilis involves Cu(II) exchange between YcnI and YcnJ

Yuri Rafael de Oliveira Silva, Grayson Barnes, Dia Zheng et al. Aug 01, 2025 pp. 110480 10.1016/j.jbc.2025.110480

Stressful situations: Molecular insights on mitochondrial quality control pathways

Sabrina Romanelli, Jean-François Trempe Aug 01, 2025 pp. 110483 10.1016/j.jbc.2025.110483

Translation-independent association of mRNAs that encode protomers of the 5-HT2A-mGlu2 receptor complex

Somdatta Saha, Javier González-Maeso Aug 01, 2025 pp. 110427 10.1016/j.jbc.2025.110427

Bioluminescence-based assays for quantifying endogenous protein interactions in live cells

Andrew L. Niles, Michael R.C. Dibble, Thomas Machleidt et al. Aug 01, 2025 pp. 110454 10.1016/j.jbc.2025.110454

Loss of integrin alpha7-mediated signaling induces a dendritic cell-like phenotype in macrophages cultured on laminin-211/221 isoforms

Nagako Yoshiba, Tomoki Maekawa, Kiyotoshi Sekiguchi et al. Aug 01, 2025 pp. 110419 10.1016/j.jbc.2025.110419

Functional analysis of amino acid substitutions within human AGT1 in a cell-based platform to support the diagnosis of primary hyperoxaluria type 1

Leonardo Gatticchi, Ilaria Bellezza, Gill Rumsby et al. Aug 01, 2025 pp. 110494 10.1016/j.jbc.2025.110494

Systematic characterization of zinc in a series of breast cancer cell lines reveals significant changes in zinc homeostasis

Mena Woyciehowsky, Portia Larson, Annika R. Stephan et al. Aug 01, 2025 pp. 110442 10.1016/j.jbc.2025.110442

Maintenance of proper phosphatidylinositol-4-phosphate level by Stt4 and Sac1 contributes to vesicular transport to and from the plasma membrane

Tomoki Sano, Makoto Nagano, Hiroki Shimamura et al. Aug 01, 2025 pp. 110410 10.1016/j.jbc.2025.110410

PTH stimulation of Rankl transcription is regulated by SIK2 and 3 and mediated by CRTC2 and 3 through action of protein phosphatases 1, 2, 4, and 5

Michael J. Mosca, Zhiming He, Nagarajan Selvamurugan et al. Aug 01, 2025 pp. 110434 10.1016/j.jbc.2025.110434

Application of NanoSIMS and isotopic labeling to analyze the spatial distribution of the plant iron chelator nicotianamine

Tomoko Nozoye, Miyuki Takeuchi, Fabian Hollmann et al. Aug 01, 2025 pp. 110478 10.1016/j.jbc.2025.110478

The GTPase κB-Ras is an essential subunit of the RalGAP tumor suppressor complex

René Rasche, Lisa Helene Apken, Sonja Titze et al. Aug 01, 2025 pp. 110460 10.1016/j.jbc.2025.110460

Understanding the substrate recognition and catalytic mechanism of 2-O-methyl fucosidases from glycoside hydrolase family 139

Zak McIver, Alicia Moraleda-Montoya, Zongjia Chen et al. Aug 01, 2025 pp. 110407 10.1016/j.jbc.2025.110407

Genetic variants linked to neurodevelopmental disorders within the β3-β4 loop of the TRIO PH2 domain release autoinhibition of GEF2 activity

Melissa G. Carrizales, Andrew D. Boulton, Anthony J. Koleske Aug 01, 2025 pp. 110429 10.1016/j.jbc.2025.110429

Proximity labeling techniques for protein–protein interaction mapping in plants

Beyza Özmen, Leonard Blaschek, Michael Ogden et al. Aug 01, 2025 pp. 110501 10.1016/j.jbc.2025.110501

Identification of SRSF9 through pooled shRNA screening links BNIP3 splicing to autophagy and metabolic reprogramming in breast cancer

Anchala Pandey, B. Jithin, Srinivas Abhishek Mutnuru et al. Aug 01, 2025 pp. 110482 10.1016/j.jbc.2025.110482

Structural biology of Parkinson’s disease-associated leucine-rich repeat kinase 2 (LRRK2)

Andres E. Leschziner Aug 01, 2025 pp. 110376 10.1016/j.jbc.2025.110376

Two stages of substrate discrimination dictate selectivity in the Escherichia coli MetNI-Q ABC transporter system

Janet G. Yang, Hulda Yuchun Chen, John H. Guardado et al. Aug 01, 2025 pp. 110493 10.1016/j.jbc.2025.110493

The metastasis-associated protein MTA3 promotes cardiac repair by inhibiting the fibroblast to myofibroblast transition during fibrosis

Xu Wang, Yihui Liu, Heng Liu et al. Aug 01, 2025 pp. 110448 10.1016/j.jbc.2025.110448

Hemoglobin β-F41K: A recombinant oxygen carrier prototype engineered for enhanced heme retention, stability, and optimal oxygenation properties

Mohd Asim Khan, Kajal Yadav, Anthony V. Signore et al. Aug 01, 2025 pp. 110477 10.1016/j.jbc.2025.110477

Regulatory mechanism of the SenX3-RegX3 two-component system in Mycobacterium smegmatis: Roles of PhoU in sensing inorganic phosphate levels

Youjin Seung, Ha-Eun Baik, Eun-Jin Park et al. Aug 01, 2025 pp. 110435 10.1016/j.jbc.2025.110435

The redox landscape of pyruvate:ferredoxin oxidoreductases reveals often conserved Fe–S cluster potentials

Sheila C. Bonitatibus, Ryan V. Pham, Andrew C. Weitz et al. Aug 01, 2025 pp. 110380 10.1016/j.jbc.2025.110380

TFAP2C drives cisplatin resistance in bladder cancer by upregulating YAP and activating β-catenin signaling

Qiufeng Pan, Changmin Zou, Zhigen Lin et al. Aug 01, 2025 pp. 110387 10.1016/j.jbc.2025.110387

Hypoxia promotes the generation of a versican-rich extracellular matrix by human coronary artery endothelial cells

Sara M. Jørgensen, Song Huang, Lasse G. Lorentzen et al. Aug 01, 2025 pp. 110459 10.1016/j.jbc.2025.110459