Journal of Biological Chemistry

Mechanistic insights into mutation in the proton-coupled folate transporter (SLC46A1) causing hereditary folate malabsorption

Prithviraj Nandigrami, I. David Goldman, Andras Fiser Mar 01, 2025 pp. 108280 10.1016/j.jbc.2025.108280

Knocking out p38α+p38β+p38γ is required to abort the myogenic program in C2C12 myoblasts and to impose uncontrolled proliferation

Navit Mooshayef, Nechama Gilad, Manju P. Mohanam et al. Mar 01, 2025 pp. 108281 10.1016/j.jbc.2025.108281

Synthetic transcription factors establish the function of nine amino acid transactivation domains of Komagataella phaffii Mxr1

Prachi Priya, Vedanth Bellad Shivashankar, Pundi N. Rangarajan Mar 01, 2025 pp. 108211 10.1016/j.jbc.2025.108211

Mobility of four structural regions drives isoform-specific properties of photoenzyme LPOR in plants

Michał Gabruk, Mateusz Łuszczyński, Katarzyna Szafran et al. Mar 01, 2025 pp. 108261 10.1016/j.jbc.2025.108261

The regulation of cell metabolism by hypoxia and hypercapnia

Ben Reddan, Eoin P. Cummins Mar 01, 2025 pp. 108252 10.1016/j.jbc.2025.108252

Leucine 7 is a key residue for mutant huntingtin–induced mitochondrial pathology and neurotoxicity in Huntington's disease

Shengrong Zhang, Shengda Wang, Zeyue Yang et al. Mar 01, 2025 pp. 108297 10.1016/j.jbc.2025.108297

USP1 promotes pancreatic cancer progression and autophagy by deubiquitinating ATG14

Leilei Li, Zhili Fan, Mengfei Liu et al. Mar 01, 2025 pp. 108190 10.1016/j.jbc.2025.108190

A BRAF-activated noncoding RNA attenuates clear cell renal cell carcinoma via repression of glucose-6-phosphate dehydrogenase

Wenjing Liu, Yueli Ni, Honggang Bai et al. Mar 01, 2025 pp. 108247 10.1016/j.jbc.2025.108247

Sodium proton exchanger NHE9 pHine-tunes exosome production by impairing Rab7 activity

Mariam Duhaini, Perla Fares, Lili Hafezi et al. Mar 01, 2025 pp. 108264 10.1016/j.jbc.2025.108264

Discovery and characterization of an FAD-dependent glucose 6-dehydrogenase

Takahiro Fujii, Michinari Honda, Wataru Fujii et al. Mar 01, 2025 pp. 108189 10.1016/j.jbc.2025.108189

Identifying the copper coordination environment between interacting neurodegenerative proteins: A new approach using pulsed EPR with 14N/15N isotopic labeling

Amanda Smart, Kevin Singewald, Zikri Hasanbasri et al. Mar 01, 2025 pp. 108311 10.1016/j.jbc.2025.108311

Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein pocket domain

Anthony Castro, Alfredo Ruiz Rivera, Chad C. Moorman et al. Mar 01, 2025 pp. 108284 10.1016/j.jbc.2025.108284

PDE4 inhibitor rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer

Arka Bagchi, Anuran Bhattacharya, Analava Bera et al. Mar 01, 2025 pp. 108239 10.1016/j.jbc.2025.108239

A quantitative intracellular peptide-binding assay reveals recognition determinants and context dependence of short linear motifs

Mythili S. Subbanna, Matthew J. Winters, Mihkel Örd et al. Mar 01, 2025 pp. 108225 10.1016/j.jbc.2025.108225

Structural insights into 2-oxindole-forming monooxygenase MarE: Divergent architecture and substrate positioning versus tryptophan dioxygenases

Inchul Shin, Romie C. Nguyen, Samuel R. Montoya et al. Mar 01, 2025 pp. 108241 10.1016/j.jbc.2025.108241

The sterol-regulating human ARV1 binds cholesterol and phospholipids through its conserved ARV1 homology domain

Jessie Lee Cunningham, Hsing-Yin Liu, Jamie Francisco et al. Mar 01, 2025 pp. 108306 10.1016/j.jbc.2025.108306

Correction: A putative cAMP-binding protein in Trypanosoma brucei cooperates with FLAM3 to promote flagellar connection and cell morphogenesis

Qing Zhou, Phu Van Nguyen, Ziyin Li Mar 01, 2025 pp. 108238 10.1016/j.jbc.2025.108238

AnimalGWASAtlas: Annotation and prioritization of GWAS loci and quantitative trait loci for animal complex traits

Yuwei Gou, Yunhan Jing, Yifei Wang et al. Mar 01, 2025 pp. 108267 10.1016/j.jbc.2025.108267

Nanobody fusion enhances production of difficult-to-produce secretory proteins

Runchuan Yan, Yan Zhang, Hui Zhang et al. Mar 01, 2025 pp. 108292 10.1016/j.jbc.2025.108292

The juxtamembrane sequence of small ankyrin 1 mediates the binding of its cytoplasmic domain to SERCA1 and is required for inhibitory activity

Yi Li, Nathan T. Wright, Robert J. Bloch Mar 01, 2025 pp. 108216 10.1016/j.jbc.2025.108216

Integrin beta 1 and fibronectin mediate extracellular vesicle uptake and functional RNA delivery

Omnia M. Elsharkasy, Willemijn S. de Voogt, Maria Laura Tognoli et al. Mar 01, 2025 pp. 108305 10.1016/j.jbc.2025.108305

Emerging approaches to investigating functional protein dynamics in modular redox enzymes: Nitric oxide synthase as a model system

Ting Jiang, Megan C. Thielges, Changjian Feng Mar 01, 2025 pp. 108282 10.1016/j.jbc.2025.108282

Metformin inhibits the histone methyltransferase CARM1 and attenuates H3 histone methylation during gluconeogenesis

Sinjini Dhang, Atanu Mondal, Chandrima Das et al. Mar 01, 2025 pp. 108271 10.1016/j.jbc.2025.108271

Anaplerosis by medium-chain fatty acids through complex interplay with glucose and glutamine metabolism

Hannah M. German, Jolita Ciapaite, Nanda M. Verhoeven-Duif et al. Mar 01, 2025 pp. 108307 10.1016/j.jbc.2025.108307

Isolation and structure elucidation of Dm-CVNH, a new cyanovirin-N homolog with activity against SARS-CoV-2 and HIV-1

Maria Orfanoudaki, Lauren R.H. Krumpe, Shilpa R. Shenoy et al. Mar 01, 2025 pp. 108319 10.1016/j.jbc.2025.108319