Journal of Biological Chemistry

Hypoxia induces ferroptotic cell death mediated by activation of the inner mitochondrial membrane fission protein MTP18/Drp1 in invertebrates

Jiaqi Liu, Xichao Sun, Yijie Wu et al. Mar 01, 2025 pp. 108326 10.1016/j.jbc.2025.108326

Tetraspanin CD9 alters cellular trafficking and endocytosis of tetraspanin CD63, affecting CD63 packaging into small extracellular vesicles

Leanne C. Duke, Allaura S. Cone, Li Sun et al. Mar 01, 2025 pp. 108255 10.1016/j.jbc.2025.108255

Mechanisms of dual modulatory effects of spermine on the mitochondrial calcium uniporter complex

Yung-Chi Tu, I-Chi Lee, Tsai-Wei Chang et al. Mar 01, 2025 pp. 108218 10.1016/j.jbc.2025.108218

p53-mediated regulation of LINE1 retrotransposon-derived R-loops

Pratyashaa Paul, Arun Kumar, Ankita Subhadarsani Parida et al. Mar 01, 2025 pp. 108200 10.1016/j.jbc.2025.108200

Drosophila Modulo is essential for transposon silencing and developmental robustness

Rasesh Y. Parikh, Dhananjaya Nayak, Haifan Lin et al. Mar 01, 2025 pp. 108210 10.1016/j.jbc.2025.108210

A CRISPR-edited isoform of the AMPK kinase LKB1 improves the response to cisplatin in A549 lung cancer cells

Matheus Brandemarte Severino, Ana Paula Morelli, Isadora Carolina Betim Pavan et al. Mar 01, 2025 pp. 108308 10.1016/j.jbc.2025.108308

Cyclophilin J limits linear ubiquitin signaling and controls colorectal cancer progression

Chunjie Sheng, Chen Yao, Jing Wang et al. Mar 01, 2025 pp. 108323 10.1016/j.jbc.2025.108323

Downregulation of the phosphatase PHLPP1 contributes to NNK-induced malignant transformation of human bronchial epithelial cells (HBECs)

Xuelei Liu, Shirui Huang, Xiaozhen Gu et al. Mar 01, 2025 pp. 108221 10.1016/j.jbc.2025.108221

Profiling Tel1 signaling reveals a non-canonical motif targeting DNA repair and telomere control machineries

William J. Comstock, Shrijan Bhattarai, Ethan J. Sanford et al. Mar 01, 2025 pp. 108194 10.1016/j.jbc.2025.108194

Binding of small molecules at the P-stalk site of ricin A subunit trigger conformational changes that extend into the active site

John E. McLaughlin, Michael J. Rudolph, Arkajyoti Dutta et al. Mar 01, 2025 pp. 108310 10.1016/j.jbc.2025.108310

Complement-activated fragment Ba functions as an antibacterial protein and mediates immune responses in lower vertebrates

Xiao-yan Jin, Hong-qiang Zhang, Zhe Feng et al. Mar 01, 2025 pp. 108278 10.1016/j.jbc.2025.108278

Colorectal cancer hot spot mutations attenuate the ASXL-MLL4 interaction

Soumi Biswas, Ji-Eun Lee, Guojia Xie et al. Mar 01, 2025 pp. 108333 10.1016/j.jbc.2025.108333

Pathogenic mechanism of abnormal expression of HDAC3 in ovulatory granulosa cells inducing oocyte maturation disorder and its application in IVM

Huarong Wang, Han Cai, Meiling Zhang et al. Mar 01, 2025 pp. 108287 10.1016/j.jbc.2025.108287

Single-cell metabolomics profiling of somatosensory neurons in various stages of neuropathic pain

Lin Yi, Tiepeng Liao, Man Yuan et al. Mar 01, 2025 pp. 108309 10.1016/j.jbc.2025.108309

A predictive chromatin architecture nexus regulates transcription and DNA damage repair

Audesh Bhat, Sonali Bhan, Aindrila Kabiraj et al. Mar 01, 2025 pp. 108300 10.1016/j.jbc.2025.108300

Maresin-1 promotes neuroprotection and modulates metabolic and inflammatory responses in disease-associated cell types in preclinical models of multiple sclerosis

Insha Zahoor, Mohammad Nematullah, Mohammad Ejaz Ahmed et al. Mar 01, 2025 pp. 108226 10.1016/j.jbc.2025.108226

An in vitro platform for the enzymatic characterization of the rhomboid protease RHBDL4

Satarupa Bhaduri, Mac Kevin E. Braza, Stancho Stanchev et al. Mar 01, 2025 pp. 108275 10.1016/j.jbc.2025.108275

NUMB alternative splicing and isoform-specific functions in development and disease

Sascha E. Dho, Kamal Othman, Yangjing Zhang et al. Mar 01, 2025 pp. 108215 10.1016/j.jbc.2025.108215

Correction: KLF6 activates Sp1-mediated prolidase transcription during TGF-β1 signaling

Ireti Eni-Aganga, Zeljka Miletic Lanaghan, Farah Ismail et al. Mar 01, 2025 pp. 108214 10.1016/j.jbc.2025.108214

Rad5 and Ubc4 directly ubiquitinate PCNA at Lys164 in vitro

Yixiong Hu, Kaiyang Liu, Xue Bai et al. Mar 01, 2025 pp. 108192 10.1016/j.jbc.2025.108192

Exogenous L-fucose attenuates depression induced by chronic unpredictable stress: Implicating core fucosylation has an antidepressant potential

Dan Wang, Tomohiko Fukuda, Tiangui Wu et al. Mar 01, 2025 pp. 108230 10.1016/j.jbc.2025.108230

Dengue virus is particularly sensitive to interference with long-chain fatty acid elongation and desaturation

Julia Hehner, Lisa Ludenia, Laura Bierau et al. Mar 01, 2025 pp. 108222 10.1016/j.jbc.2025.108222

The levels of the long noncoding RNA MALAT1 affect cell viability and modulate TDP-43 binding to mRNA in the nucleus

Adarsh Balaji, Aileen C. Button, Simone D. Hall et al. Mar 01, 2025 pp. 108207 10.1016/j.jbc.2025.108207

RNA G-quadruplexes regulate mammalian mirtron biogenesis

Uzma Salim, Manoj B. Menon, Sonam Dhamija et al. Mar 01, 2025 pp. 108276 10.1016/j.jbc.2025.108276

Biomedical effects of protein arginine methyltransferase inhibitors

Mengtong Cao, Terry Nguyen, Jiabao Song et al. Mar 01, 2025 pp. 108201 10.1016/j.jbc.2025.108201