Journal of Biological Chemistry

Dynein light chains 1 and 2 are auxiliary proteins of pH-sensitive Kir4.1 channels

Sun-Joo Lee, Jian Gao, Ellen Thompson et al. Apr 01, 2025 pp. 108393 10.1016/j.jbc.2025.108393

G protein–coupled estrogen receptor deficiency exacerbates demyelination through microglial ferroptosis

Xiaojuan Mi, Junjie Li, Ziqi Feng et al. Apr 01, 2025 pp. 108312 10.1016/j.jbc.2025.108312

CCCTC-binding factor N-terminal domain regulates clustered protocadherin gene expression by enhancing cohesin processivity

Yijun Zhang, Qiang Wu Apr 01, 2025 pp. 108337 10.1016/j.jbc.2025.108337

Epitomic profiling and functional characteristics of pemphigus vulgaris autoantibody binding to keratinocyte M3 muscarinic acetylcholine receptor

Jorge Mauricio Reyes-Ruiz, Alex Chernyavsky, Sergei A. Grando et al. Apr 01, 2025 pp. 108434 10.1016/j.jbc.2025.108434

Mutant protein chemical rescue: From mechanisms to therapeutics

Timothy R. O'Meara, Brad A. Palanski, Maggie Chen et al. Apr 01, 2025 pp. 108417 10.1016/j.jbc.2025.108417

Cryo-EM structure of apo-form human DNA polymerase δ elucidates its minimal DNA synthesis activity without PCNA

Yeonoh Shin, Mark Hedglin, Katsuhiko S. Murakami Apr 01, 2025 pp. 108342 10.1016/j.jbc.2025.108342

The molecular basis of immunosuppression by soluble CD52 is defined by interactions of N-linked and O-linked glycans with HMGB1 box B

Nicholas J. DeBono, Silvia D’Andrea, Esther Bandala-Sanchez et al. Apr 01, 2025 pp. 108350 10.1016/j.jbc.2025.108350

Structural basis of a distinct α-synuclein strain that promotes tau inclusion in neurons

Chuanqi Sun, Kang Zhou, Peter DePaola et al. Apr 01, 2025 pp. 108351 10.1016/j.jbc.2025.108351

Not all 5′-deoxyadenosines are created equal: Tracing the provenance of 5′-deoxyadenosine formed by the radical S-adenosyl-L-methionine enzyme 7-carboxy-7-deazaguanine synthase

Saswata Nayak, Andrew S. Jochimsen, Vahe Bandarian Apr 01, 2025 pp. 108347 10.1016/j.jbc.2025.108347

Ovarian tachykinin signaling system induces the growth of secondary follicles during the gonadotropin-independent process

Tsuyoshi Kawada, Masato Aoyama, Shin Matsubara et al. Apr 01, 2025 pp. 108375 10.1016/j.jbc.2025.108375

Emerging concepts in the molecular cell biology and functions of mammalian erythrocytes

Sangeetha Devi Kumar, Japita Ghosh, Swati Ghosh et al. Apr 01, 2025 pp. 108331 10.1016/j.jbc.2025.108331

ATP synthesis of Enterococcus hirae V-ATPase driven by sodium motive force

Akihiro Otomo, Lucy Gao Hui Zhu, Yasuko Okuni et al. Apr 01, 2025 pp. 108422 10.1016/j.jbc.2025.108422

Pyruvate dehydrogenase kinase 1 controls triacylglycerol hydrolysis in cardiomyocytes

Michael G. Atser, Chelsea D. Wenyonu, Elyn M. Rowe et al. Apr 01, 2025 pp. 108398 10.1016/j.jbc.2025.108398

Cargo adaptor identity controls the mechanism and kinetics of dynein activation

John P. Gillies, Saffron R. Little, Aravintha Siva et al. Apr 01, 2025 pp. 108358 10.1016/j.jbc.2025.108358

Pak1 dysregulates pyruvate metabolism in PDAC cells by exerting a phosphorylation-mediated regulatory effect on PDHA1

Sowmiya Murugan, Srikanth Swamy Swaroop B, Prarthana Gopinath et al. Apr 01, 2025 pp. 108409 10.1016/j.jbc.2025.108409

Microvillus inclusion disease-causing MYO5B point mutations exert differential effects on motor function

Deanna M. Bowman, Leslie M. Meenderink, Kyra S. Thomas et al. Apr 01, 2025 pp. 108328 10.1016/j.jbc.2025.108328

Cryo-EM structures define the electron bifurcating flavobicluster and ferredoxin binding site in an archaeal Nfn-Bfu transhydrogenase

Xiansha Xiao, Gerrit J. Schut, Xiang Feng et al. Apr 01, 2025 pp. 108410 10.1016/j.jbc.2025.108410

In vitro reconstitution reveals substrate selectivity of protein S-acyltransferases

Tanmay Mondal, James Song, Anirban Banerjee Apr 01, 2025 pp. 108406 10.1016/j.jbc.2025.108406

O-GlcNAcylation modification of MyoD regulates skeletal muscle fiber differentiation by antagonizing the UPF1 pathway

Lele Kou, Meng Zhang, Xiaoshuang Li et al. Apr 01, 2025 pp. 108364 10.1016/j.jbc.2025.108364

Structure-function studies of a nucleoplasmin isoform from Plasmodium falciparum

Ketul Saharan, Somanath Baral, Surajit Gandhi et al. Apr 01, 2025 pp. 108379 10.1016/j.jbc.2025.108379

An alternative adaptation strategy of the CCA-adding enzyme to accept noncanonical tRNA substrates in Ascaris suum

Valerie Thalhofer, Claudius Doktor, Lena Philipp et al. Apr 01, 2025 pp. 108414 10.1016/j.jbc.2025.108414

Requirements for nuclear GRP78 transcriptional regulatory activities and interaction with nuclear GRP94

Ze Liu, Dat P. Ha, Liangguang Leo Lin et al. Apr 01, 2025 pp. 108369 10.1016/j.jbc.2025.108369

Structural insight into the catalytic mechanism of the bifunctional enzyme l-fucokinase/GDP-fucose pyrophosphorylase

Sheng-Wei Lin, Tzu-Ping Ko, Hung-Yu Chiang et al. Apr 01, 2025 pp. 108344 10.1016/j.jbc.2025.108344

The structural basis of TRIM25-mediated regulation of RIG-I

Yunlong Li, Siqi Wu, Xuyang Tian et al. Apr 01, 2025 pp. 108367 10.1016/j.jbc.2025.108367

Upregulation of the interferon-inducible antiviral gene RSAD2 in neuroendocrine prostate cancer via PVT1 exon 9 dependent and independent pathways

Rachel E. Bonacci, Meghan McGill, Nu Thuy Anh Le et al. Apr 01, 2025 pp. 108370 10.1016/j.jbc.2025.108370