A farnesoid X receptor T296I variant disrupts ligand-induced FXR activation and thus bile acid transport in progressive familial intrahepatic cholestasis
A
Annika Behrendt
A
Alex Bastianelli
J
Jan Stindt
E
Eva-Doreen Pfister
M
Malte Sgodda
T
Tobias Cantz
S
Sebastian Hook
M
Mohanraj Gopalswamy
K
Kathrin Grau
S
Stefanie Brands
C
Carola Dröge
A
Amelie Stalke
M
Michele Bonus
S
Sabine Franke
U
Ulrich Baumann
V
Verena Keitel
H
Holger Gohlke
Article Details
Journal
Journal of Biological Chemistry
Volume / Issue
Vol. 301, Issue 11
Published
November 01, 2025
Pages
110769
ISSN
0021-9258
Publisher
Elsevier BV
Authors (17)
A
Annika Behrendt
A
Alex Bastianelli
J
Jan Stindt
E
Eva-Doreen Pfister
M
Malte Sgodda
T
Tobias Cantz
S
Sebastian Hook
M
Mohanraj Gopalswamy
K
Kathrin Grau
S
Stefanie Brands
C
Carola Dröge
A
Amelie Stalke
M
Michele Bonus
S
Sabine Franke
U
Ulrich Baumann
V
Verena Keitel
H
Holger Gohlke
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