Journal of Biological Chemistry

O-GlcNAc transferase couples nutrient availability to synaptic plasticity in paraventricular neurons to regulate satiety

Mario Pérez-del-Pozo, Manish Bhattacharjee, Anushree Tripathi et al. Feb 01, 2026 pp. 111124 10.1016/j.jbc.2025.111124

A revised model of nuclear actin import: Importin 9 competes with cofilin, profilin, and RanGTP for actin binding

Amanda J. Keplinger, Prithi A. Srinivasan, Sarah M. Christensen et al. Feb 01, 2026 pp. 111123 10.1016/j.jbc.2025.111123

Cantu syndrome–associated SUR2[H60Y] mutation confers selective gain of function on Kir6.1 ATP-sensitive potassium channels

Jian Gao, Ellen T. Thompson, Colin G. Nichols Feb 01, 2026 pp. 111105 10.1016/j.jbc.2025.111105

Elevated adipose inflammation, but reduced hepatic triacylglycerol storage in diet-induced obese Plin4−/− mice

Atanaska Ivanova Doncheva, Ryoko Higa, Prabhat Khanal et al. Feb 01, 2026 pp. 111043 10.1016/j.jbc.2025.111043

Global discovery of RNA modifications and functional analysis of m5C methylome in cyanobacteria

Gaoxiang Cao, Mingtian Ling, Jiao Zhan et al. Feb 01, 2026 pp. 111133 10.1016/j.jbc.2026.111133

Lipopolysaccharide induces HIF-1α accumulation via MAPK p38–mediated mRNA stabilization and dexamethasone-sensitive protein stabilization

Chloe Lockwood, Kalbinder K. Daley, John D. O’Neil et al. Feb 01, 2026 pp. 111094 10.1016/j.jbc.2025.111094

Protein tyrosine kinase Src suppresses hepatitis C virus particle release through regulation of Ndrg1

Leihua Fu, Kenji Takeuchi, Kazuyasu Chihara et al. Feb 01, 2026 pp. 111125 10.1016/j.jbc.2025.111125

Temperature downshifts induce biofilm formation in Pseudomonas aeruginosa through the SiaABCD signal and functional module

Yanran Li, Zhe Chen, Tingying Xia et al. Feb 01, 2026 pp. 111086 10.1016/j.jbc.2025.111086

Mitotic chromatin compaction tethers extrachromosomal DNA to chromosomes and prevents their mis-segregation into micronuclei

Lu M. Yang Feb 01, 2026 pp. 111081 10.1016/j.jbc.2025.111081

The cytochrome c oxidase subunit COX6B1 is required for redox-sensitive early assembly and late stabilization of complex IV

Kristýna Čunátová, Marek Vrbacký, Michal Knězů et al. Feb 01, 2026 pp. 111070 10.1016/j.jbc.2025.111070

Structural basis underlying the autoinhibition of the formin FHOD1 and its phosphorylation-dependent activation

Mokhamad Fahmi Rizki Syaban, Shafiyyah Maratush Shalihah, Yohko Kage et al. Feb 01, 2026 pp. 111109 10.1016/j.jbc.2025.111109

Oligomerization is required for channel formation of MctB and for copper resistance of Mycobacterium tuberculosis

Axel Siroy, Demeng Sun, Avraneel Paul et al. Feb 01, 2026 pp. 111037 10.1016/j.jbc.2025.111037

VarLand: A pipeline to map the structural landscape of missense variants at the proteome scale

Francisco J. Guzmán-Vega, Kelly J. Cardona-Londoño, Ana C. González-Álvarez et al. Feb 01, 2026 pp. 111071 10.1016/j.jbc.2025.111071

IRF1 is a context-dependent homeostatic gatekeeper of basal immunity and antiviral readiness

Eyal Zoler, Irina Miodownik, Shifra Ben-Dor et al. Feb 01, 2026 pp. 111118 10.1016/j.jbc.2025.111118

A luminescent reporter assay to quantify SORL1 ectodomain shedding and retromer-dependent endosome recycling activity

Elnaz Fazeli, Asad Jan, Ann-Kathrin Huber et al. Feb 01, 2026 pp. 111136 10.1016/j.jbc.2026.111136

Gene expression analysis and proximity labeling reveal post-transcriptional functions of the yeast RNA polymerase II regulator Def1

Oluwasegun T. Akinniyi, Shardul Kulkarni, Mikayla M. Hribal et al. Feb 01, 2026 pp. 111003 10.1016/j.jbc.2025.111003

The divergent roles of tryptophans W354 and W217 in OCT1 transport: Similar localization, distinct functions

Sarah Römer, Lennart Ebel, Anna Neumann et al. Feb 01, 2026 pp. 111051 10.1016/j.jbc.2025.111051

Identification of receptor-binding domains of Bacteroidales antibacterial pore-forming toxins

Sofia Borgini, Edwin Pasveer, Chloé Petre et al. Feb 01, 2026 pp. 111113 10.1016/j.jbc.2025.111113

A high diversity naïve variable new antigen receptor, vNAR, phage library for rapid nanobody discovery across diverse antigens

Vivek Kumar, Kuldeep Jangid, B. Santhosh et al. Feb 01, 2026 pp. 111083 10.1016/j.jbc.2025.111083

CDC123 is an ATPase that modulates mRNA translation and the integrated stress response by regulating eIF2 complex assembly

Anthony L. Erb, Sara K. Young-Baird Feb 01, 2026 pp. 111116 10.1016/j.jbc.2025.111116

The biosynthesis of N-acylated tryptazolone in Mycobacterium tuberculosis and related bacteria

Julia Kleetz, Jason C. Grigg, Adam A. Hassan et al. Feb 01, 2026 pp. 111079 10.1016/j.jbc.2025.111079

GRK phosphorylation drives β-arrestin–independent internalization of chemokine receptor CXCR5

Joseph M. Crecelius, Ya Zhuo, Aaren R. Manz et al. Feb 01, 2026 pp. 111114 10.1016/j.jbc.2025.111114

Sphingosine-1-phosphate receptor 2 inhibition ameliorates familial exudative vitreoretinopathy models

Hirad A. Feridooni, Rachel Fody, Mahtab Tavasoli et al. Feb 01, 2026 pp. 111107 10.1016/j.jbc.2025.111107

UBE2I promotes immune infiltration and tumor progression in thyroid cancer and modulates hnRNPA2B1 SUMOylation

Jinmiao Wang, Minghan Qiu, Li Dong et al. Feb 01, 2026 pp. 111091 10.1016/j.jbc.2025.111091

The RNA-binding protein hnRNP E1 regulates p53 and p21 translation via KH1 and KH2 domain interactions with 3′ UTR C-rich motifs

Abhisekh Samanta, Arpita Kar, Sandipan Mukherjee et al. Feb 01, 2026 pp. 111042 10.1016/j.jbc.2025.111042