Journal of Biological Chemistry

Electromotility can be disassociated from gating charge movement in outer hair cells of conditional alpha2 spectrin knockout mice

Jun-Ping Bai, Micheal C. Stankewich, Jie Yang et al. Mar 01, 2026 pp. 111226 10.1016/j.jbc.2026.111226

Contribution of organic anion transporting polypeptides to bile acid uptake in the Caco-2 cell monolayer and gastrointestinal tract

Yuki Kurobe-Takashima, Kota Yanagisawa, Yuta Saito et al. Mar 01, 2026 pp. 111205 10.1016/j.jbc.2026.111205

A GluN2B disease-associated variant promotes the degradation of NMDA receptors via autophagy

Taylor M. Benske, Marnie P. Williams, Pei-Pei Zhang et al. Mar 01, 2026 pp. 111147 10.1016/j.jbc.2026.111147

Engineering an orthogonal ubiquitin transfer cascade with RING E3 RNF38 by phage display to reveal its regulation of nuclear transport

Li Zhou, In Ho Jeong, Hang Li et al. Mar 01, 2026 pp. 111199 10.1016/j.jbc.2026.111199

HIF-2α induction in de novo lipogenesis in metabolic dysfunction-associated steatohepatitis is dependent on IL-21 signaling

Karla K. Frietze, Alyssa Brown, Dividutta Das et al. Mar 01, 2026 pp. 111212 10.1016/j.jbc.2026.111212

An evolutionarily conserved salt bridge stabilizes the active site for GTP hydrolysis in Rho GTPases

Kendra Marcus, Michael Schwabe, Ryan Knihtila et al. Mar 01, 2026 pp. 111260 10.1016/j.jbc.2026.111260

Hypoxia-inducible factor 1αa regulates lipid metabolism to coordinate adipocyte hypertrophy and hyperplasia in grass carp

Mingkui Wei, Zhiqi Tian, Lei Song et al. Mar 01, 2026 pp. 111195 10.1016/j.jbc.2026.111195

The KANSL1-ARL17A fusion gene generates oncogenic chKANSARL and F-circKA RNAs that synergistically drive lung cancer progression via a novel F-circKA/miR-6860/chKANSARL axis

Xinchao Guan, Tao Liu, Sili Chen et al. Mar 01, 2026 pp. 111170 10.1016/j.jbc.2026.111170

Effect of pH on small-molecule inhibitor binding to influenza virus hemagglutinin

Varada Anirudhan, Irina Gaisina, Amir Shimon et al. Mar 01, 2026 pp. 111150 10.1016/j.jbc.2026.111150

Phosphorylation-dependent regulation of serine/arginine-rich proteins and U2AF1 interactions in early spliceosome assembly

Zihan Zhang, Puspa Kunwar, Yanbao Yu et al. Mar 01, 2026 pp. 111222 10.1016/j.jbc.2026.111222

Multilineage differentiating stress-enduring cells alleviate neuropathic pain in mice through TGF-β and IL-10-dependent anti-inflammatory signaling

Yayu Zhao, Ying Fei, Yunyun Cai et al. Mar 01, 2026 pp. 111270 10.1016/j.jbc.2026.111270

Chronological lifespan extension and nucleotide salvage inhibition in yeast by isonicotinamide supplementation

Agata I. Kalita, Christopher T. Letai, Elisa Enriquez-Hesles et al. Mar 01, 2026 pp. 111158 10.1016/j.jbc.2026.111158

Time-dependent changes in meibum lipid composition and progression of dry eye following disruption of the fatty acid elongase Elovl1

Himari Tada, Keisuke Jojima, Taiga Hiranuma et al. Mar 01, 2026 pp. 111160 10.1016/j.jbc.2026.111160

Motif V is an allosteric couple between the SARS-CoV-2 nsp13 nucleotide triphosphatase and helicase active sites

Michael A. Mingroni, Brooke M. Enney, Lauren E. Malsick et al. Mar 01, 2026 pp. 111198 10.1016/j.jbc.2026.111198

F2,6BP restores mitochondrial genome integrity in Huntington’s disease

Anirban Chakraborty, Santi M. Mandal, Mikita Mankevich et al. Mar 01, 2026 pp. 111156 10.1016/j.jbc.2026.111156

A high-throughput screen for nucleolar function reveals a role for the signaling protein, SPRR3, in ribosome biogenesis

Emily C. Sutton, Carson J. Bryant, Janina I.S. Gbenoba et al. Mar 01, 2026 pp. 111132 10.1016/j.jbc.2026.111132

A new family of TonB-dependent copper transporters linked to respiratory oxidase function

Majda Hachmi, Manon Mirgaux, René Wintjens et al. Mar 01, 2026 pp. 111180 10.1016/j.jbc.2026.111180

A brain-gut excitatory peptide/CCHamide homolog regulates satiation and motivational state transitions in the Aplysia feeding circuit

Cui-Ping Liu, Ping Fu, Daniel Pang et al. Mar 01, 2026 pp. 111257 10.1016/j.jbc.2026.111257

Molecular mechanisms of mitochondrial AAA+ proteases

S. Quinn W. Currie, Monica M. Goncalves, Aaron D. Schimmer et al. Mar 01, 2026 pp. 111264 10.1016/j.jbc.2026.111264

Loss of ATM causes R-loop–associated transcriptional dysregulation and attenuates the related response to DNA damage

Katherine R. Westover, Yingzi Hou, Feng Wang et al. Mar 01, 2026 pp. 111161 10.1016/j.jbc.2026.111161

Pex6 and ubiquitination regulate topological remodeling of the peroxisomal membrane protein Pex14

Takehiko Yasumitsu, Yuichi Yagita, Yukio Fujiki et al. Mar 01, 2026 pp. 111203 10.1016/j.jbc.2026.111203

CEP55 promotes prostate cancer progression via TPX2-dependent activation of AURKA–PI3K–AKT signaling and inhibition of ferroptosis

Lizhe Xu, Jinzhuo Ning, Jinrun Wang et al. Mar 01, 2026 pp. 111218 10.1016/j.jbc.2026.111218

Correction: Abstract 2280 Time To Be Knowledgeable 1n TTBK1

James Greig, Dililah Hao, Elva (Wankun) Liang et al. Mar 01, 2026 pp. 111228 10.1016/j.jbc.2026.111228

The cytoplasmic protein YedX is a potent inhibitor of CsgA amyloid assembly in E. coli

Bharat Gurnani, Neha Jain Mar 01, 2026 pp. 111201 10.1016/j.jbc.2026.111201

A conserved salt bridge network stabilizes the hepatic organic anion transporters OATP1B1 and OATP1B3

Drew Barber, Fiona Naughton, Niek van Hilten et al. Mar 01, 2026 pp. 111217 10.1016/j.jbc.2026.111217