Journal of Biological Chemistry

A novel autopolysialylation activity of the ganglioside sialyltransferase ST8Sia5 regulates its secretion and enzyme activity

Fumiya Sakamoto, Rina Hatanaka, Masaya Hane et al. Jul 01, 2026 pp. 113106 10.1016/j.jbc.2026.113106

Prenatal cannabinoid exposure alters excitation-inhibition balance through glutamate and GABA receptor-mediated signaling

Priyanka D. Pinky, Warren D. Smith, Miles T. Wiley et al. Jul 01, 2026 pp. 113196 10.1016/j.jbc.2026.113196

DNA methylation, nucleic acid structure, and rett mutations tune MeCP2 binding affinity and cooperativity

Manana Melikishvili, Matthew Rea, Colt Capan et al. Jul 01, 2026 pp. 113227 10.1016/j.jbc.2026.113227

Nuclear translocation of triosephosphate isomerase 1 under aerobic glycolytic conditions is associated with HIV-1 transcription

Towa Abe, Tae Yasutake, Satoshi Miura et al. Jul 01, 2026 pp. 113148 10.1016/j.jbc.2026.113148

Hexosamine biosynthesis drives hemocyanin O-GlcNAcylation to potentiate antibacterial immunity in shrimp

Qian Feng, Maoshuai Fu, Wei Wang et al. Jul 01, 2026 pp. 113213 10.1016/j.jbc.2026.113213

Proximal labeling of the Golgi secretome reveals fat body–derived humoral factors in Drosophila disc regeneration

Yutaka Yoshida, Soshiro Kashio, Masayuki Miura Jul 01, 2026 pp. 113198 10.1016/j.jbc.2026.113198

Correction: Colchicine inhibits vascular calcification by suppressing inflammasome activation through the enhancement of the Sirt2-PP2Ac signaling pathway

Shu Yang, Heming Huang, Kewei Jiang et al. Jul 01, 2026 pp. 113171 10.1016/j.jbc.2026.113171

The Rho guanine-nucleotide exchange factor P-Rex2 exhibits structural and regulatory features distinct from the related RhoGEF P-Rex1

Lauren K. Anderson, Rohan Marde, Grace Muma et al. Jul 01, 2026 pp. 113229 10.1016/j.jbc.2026.113229

Titin cleavage in living cardiomyocytes induces sarcomere disassembly but does not trigger cell proliferation

Maria Rosaria Pricolo, Miguel A. López-Unzu, Natalia Vicente et al. Jul 01, 2026 pp. 113167 10.1016/j.jbc.2026.113167

Parasite-specific essential bromodomain protein TgBDP4 is a key epigenetic reader and a potential drug target for the parasite Toxoplasma gondii

Rajkumar Gurupwar, Chitti Raju Khandavalli, Abhijit S. Deshmukh Jul 01, 2026 pp. 113160 10.1016/j.jbc.2026.113160

Basigin (CD147) and calpain 4 (CapnS1) are partners in the generation of traction force but not in mechanosensing

Jacob DeTone, Savannah Kozole, Mia Stewart et al. Jul 01, 2026 pp. 113170 10.1016/j.jbc.2026.113170

HPV16 E2 protein possesses intrinsic helicase activity and sterically hinders E1 function through direct interaction

Ping Xu, Shuning Cai, Lihong Zhang et al. Jul 01, 2026 pp. 113143 10.1016/j.jbc.2026.113143

Structural basis of glucosinolate recognition and polyspecific transport by the glucosinolate transporter GTR1

Jing Nan, Hao Xu, Sisi Kang et al. Jul 01, 2026 pp. 113190 10.1016/j.jbc.2026.113190

Correction: A p.N92K variant of the GTPase RAC3 disrupts cortical neuron migration and axon elongation

Ryota Sugawara, Keisuke Hamada, Hidenori Ito et al. Jul 01, 2026 pp. 113219 10.1016/j.jbc.2026.113219

Acid-sensing ion channel 2a assembles with epithelial Na+ channel β and γ subunits to form mechanosensitive ion channels

Shujie Shi, Sarah Christine M. Whelan, Kennedy G. Szekely et al. Jul 01, 2026 pp. 113151 10.1016/j.jbc.2026.113151

Structure of a stand-alone homodimeric nonribosomal peptide synthetase condensation domain reveals occlusion of the canonical carrier-protein interface

Jitendra Singh, Thomas D. Grant, Andrew M. Gulick Jul 01, 2026 pp. 113208 10.1016/j.jbc.2026.113208

p53 regulates mitochondrial function and alpha-synuclein aggregation in Parkinson's disease

Kaiying Hou, Jialin Chen, Yuxin Xie et al. Jul 01, 2026 pp. 113184 10.1016/j.jbc.2026.113184

Global identification of Chromobacterium violaceum T6SS effectors reveals an Rhs antibacterial toxin featuring FIX and ADP-ribosyltransferase domains

Júlia A. Alves, Genady Pankov, Andrew M. Frey et al. Jul 01, 2026 pp. 113216 10.1016/j.jbc.2026.113216

A high-sensitivity strategy to screen NAD(P)H-dependent reductase activity by coupled enzyme cascade

Trisha Ghosh, Jacob Sicheri, David H. Kwan Jul 01, 2026 pp. 113135 10.1016/j.jbc.2026.113135

Functional characterization of UHRF1 variants in facilitating DNA methylation

Bigang Liu, Kaila Nayvelt, Swanand Hardikar et al. Jul 01, 2026 pp. 113149 10.1016/j.jbc.2026.113149

Atomistic scattering modeling of the solution structure of human dimeric IgA1 reveals a structural and mechanistic basis for IgA nephropathy

Jayesh S. Bhatt, See Cheng Yeo, Sam M. Ireland et al. Jul 01, 2026 pp. 113156 10.1016/j.jbc.2026.113156

A side-by-side biophysical comparison of five single-domain antibody scaffolds used for synthetic display libraries

Marlene Rauschmayer, Mustafa Abdellatif, Anna Chubanova et al. Jul 01, 2026 pp. 113155 10.1016/j.jbc.2026.113155

Creatine metabolism regulates trophectoderm formation in early mouse embryos via an energy-cytoskeleton-YAP axis

Xiangyi Chen, Bo Pan, Jianpeng Qin et al. Jul 01, 2026 pp. 113147 10.1016/j.jbc.2026.113147

HIF-1α drives distinct aspects of hypoxia-induced glucose metabolism in intestinal epithelial cells

Sarah J. Kierans, Ciarán Kennedy, Rory Turner et al. Jul 01, 2026 pp. 113193 10.1016/j.jbc.2026.113193

Constitutive activation of a hybrid two-component regulator reveals cross-regulation of polysaccharide utilization genes in Bacteroides

Rong Gao, Brynn Sillick, Leonard M. Thomas et al. Jul 01, 2026 pp. 113195 10.1016/j.jbc.2026.113195