Journal of Biological Chemistry

The chromatin remodeling factor BAP18 promotes non–small cell lung cancer progression via the recruitment of β-catenin with the transcriptional coactivator complex ACTL6A–PAF1

Junli Hao, Qilin Hu, Xin Li et al. Sep 01, 2025 pp. 110596 10.1016/j.jbc.2025.110596

TGF-β1-dependent expression of FOXS1 attenuates adipogenic potential and enhances a myofibroblast cellular phenotype

Alexander H. Tavares, Scott P. Connelly, Daryn Maksat et al. Sep 01, 2025 pp. 110563 10.1016/j.jbc.2025.110563

Correction: of HSD3B1 upregulation via LRH1 sustains estrogen receptor signaling and promotes endocrine resistance in breast cancer

Xiuxiu Li, Yoon-Mi Chung, Monaben Patel et al. Sep 01, 2025 pp. 110553 10.1016/j.jbc.2025.110553

The E3 ubiquitin ligase MARCHF8 restricts HSV-1 infection by inhibiting replication of the viral genome

Yongyan Xia, L. Rayburn Nigos, Fernando Villalón-Letelier et al. Sep 01, 2025 pp. 110567 10.1016/j.jbc.2025.110567

Molecular basis of the autoregulatory mechanism of motor neuron-related splicing factor 30

Keiichi Izumikawa, Tatsuya Shida, Yuuka Onodera et al. Sep 01, 2025 pp. 110522 10.1016/j.jbc.2025.110522

Visualization of covalent intermediates and conformational states of proline utilization A by X-ray crystallography and molecular dynamics simulations

David P. Buckley, Donald F. Becker, John J. Tanner Sep 01, 2025 pp. 110532 10.1016/j.jbc.2025.110532

Association of protein arginine deiminase 4 with the myosin-9 motor complex

Xiaoxing Wang, Fatemeh Moadab, Farheen Shaikh et al. Sep 01, 2025 pp. 110513 10.1016/j.jbc.2025.110513

Ubiquitin-specific protease 7-mediated stabilization of discoidin domain receptor 1 drives progression of TP53-Mutant cancers

Yiying Xue, Bing Xiu, Muye Yang et al. Sep 01, 2025 pp. 110515 10.1016/j.jbc.2025.110515

Nootropic benzothiazoles promote dendritic spine formation by targeting fascin-1

Aashish Shivkumar, Kyle R. Berg, Kevin C. Sibucao et al. Sep 01, 2025 pp. 110572 10.1016/j.jbc.2025.110572

The urokinase receptor/uPAR is a major effector of p53 gain-of-function mutations in gemcitabine-treated pancreatic ductal adenocarcinoma

Carlotta Zampieri, Kourosh Kouhmareh, Parnian Sartipdolagh et al. Sep 01, 2025 pp. 110561 10.1016/j.jbc.2025.110561

The pyruvate dehydrogenase complex in concert with the DNA/RNA-binding protein YBX1 regulates cell senescence and tumorigenesis

Huan Chen, Jing Shi, Qiuping Wang et al. Sep 01, 2025 pp. 110585 10.1016/j.jbc.2025.110585

Nuclear basket proteins Nup2 and Mlp1 drive heat shock–induced 3D genome restructuring downstream of transcriptional activation

Suman Mohajan, Linda S. Rubio, David S. Gross Sep 01, 2025 pp. 110568 10.1016/j.jbc.2025.110568

The regulation of lipid A biosynthesis

Katherine R. Hummels Sep 01, 2025 pp. 110556 10.1016/j.jbc.2025.110556

Structural basis of transglucosylation in dextran dextrinase, a homolog of anomer-inverting GH15 glucoside hydrolases

Takayoshi Tagami, Wataru Saburi, Juri Sadahiro et al. Sep 01, 2025 pp. 110541 10.1016/j.jbc.2025.110541

Inactivation of cellular retinol-binding protein 1 protects against bis-retinoid accumulation and light-induced retinal degeneration in mice

Made Airanthi K. Widjaja-Adhi, Jaclyn Swigris, Jacqueline Plau et al. Sep 01, 2025 pp. 110538 10.1016/j.jbc.2025.110538

Regulation of the MDM2-p53 nexus by a nuclear phosphoinositide and small heat shock protein complex

Jeong Hyo Lee, Mo Chen, Tianmu Wen et al. Sep 01, 2025 pp. 110527 10.1016/j.jbc.2025.110527

Nanoscale chemical imaging of phagocytosis: A battle for metals between host and microbe

Nadeem Ullah, Björn De Samber, Nathalie Uwamahoro et al. Sep 01, 2025 pp. 110485 10.1016/j.jbc.2025.110485

Constitutively active orphan G protein-coupled receptors through the lenses of cryo-electron microscopy

Josep Argerich, Daniel Muñoz-Reyes, Iris del Val-García et al. Sep 01, 2025 pp. 110571 10.1016/j.jbc.2025.110571

Leveraging RNA-seq deconvolution to improve complex in vitro model characterization

Brad C. Hansen, Christopher M. Arian, Yuting Zeng et al. Sep 01, 2025 pp. 110510 10.1016/j.jbc.2025.110510

Proximity-dependent proteomics and network analysis of adenylyl cyclase isoforms 5, 6, and 9 in cardiomyocytes

Taeyeop Park, Yong Li, Neha Arora et al. Sep 01, 2025 pp. 110539 10.1016/j.jbc.2025.110539

Integrating deep learning for post-translational modifications crosstalk on Hsp90 and drug binding

Jennifer A. Heritz, Katherine A. Meluni, Sarah J. Backe et al. Sep 01, 2025 pp. 110519 10.1016/j.jbc.2025.110519

Manganese-dependent iron-superoxide dismutase drives Acinetobacter baumannii fitness during oxidative stress

Ashish Kumar Ray, Somok Bhowmik, Snehlata Saini et al. Sep 01, 2025 pp. 110549 10.1016/j.jbc.2025.110549

Variants of the Ebola virus matrix protein VP40 have differential effects on oligomerization and plasma membrane interactions

Balindile B. Motsa, Barsha Bhowal, Yogesh B. Narkhede et al. Sep 01, 2025 pp. 110489 10.1016/j.jbc.2025.110489

Disulfide bond-mediated stabilization of the oligomers of UDP-glucuronosyltransferase 2B7

Yuu Miyauchi, Haruna Koba, Madoka Sawai et al. Sep 01, 2025 pp. 110502 10.1016/j.jbc.2025.110502

In-depth analysis of the tear fluid glycoproteome reveals diverse lacritin glycosylation and spliceoforms

Vincent Chang, Keira E. Mahoney, Isaac Lian et al. Sep 01, 2025 pp. 110580 10.1016/j.jbc.2025.110580