Journal of Biological Chemistry

Decoding the glycan shield: Immune recognition and response to the HIV-1 envelope trimer

Fathima Zahra Nawaz, Trevor M. Adams, Mariye Erol Demirturk et al. Apr 01, 2026 pp. 111350 10.1016/j.jbc.2026.111350

Temperature-dependent conformational dynamics govern regioselectivity in a CYP152 decarboxylase

Mayara C. Avila, Leticia L. Rade, Amanda S. Souza et al. Apr 01, 2026 pp. 111309 10.1016/j.jbc.2026.111309

A monofunctional-like mutant of DNA glycosylase NTHL1 changes the dynamics of DNA repair during acute oxidative stress

James Haslam, Natalie Rudolfova, Kaixin Zhou et al. Apr 01, 2026 pp. 111332 10.1016/j.jbc.2026.111332

Targeting the Golgi apparatus enhances PD-L1 blockade and synergizes with oxaliplatin to improve immunotherapy efficacy

Haohuan Li, Chao Cui, Chenglu Sun et al. Apr 01, 2026 pp. 111343 10.1016/j.jbc.2026.111343

HEXIM1/P–TEFb complex controls RNA polymerase II pause release and immediate early gene induction following neuronal depolarization

Myo Htet, Camila Estay-Olmos, Lan Hu et al. Apr 01, 2026 pp. 111325 10.1016/j.jbc.2026.111325

Thymine DNA glycosylase binds to R-loops and excises 5-formyl and 5-carboxyl cytosine from DNA/RNA hybrids

Baiyu Zhu, Lakshmi S. Pidugu, Mary E. Cook et al. Apr 01, 2026 pp. 111308 10.1016/j.jbc.2026.111308

Acetic acid induces proteasome storage granule formation and inhibits proteasomal proteolysis: Comparison with other induction conditions

Mitsuki Imajo, Shoei Tanaka, Vo Thi Anh Nguyet et al. Apr 01, 2026 pp. 111297 10.1016/j.jbc.2026.111297

Stability and interaction defects in the Sin3A-PAH1 αα-hub domain associated with loss-of-function variants

Amanda D. Due, Sigrid Jørsboe, Louise T. Jensen et al. Apr 01, 2026 pp. 111312 10.1016/j.jbc.2026.111312

Cosolute effects reveal the nature of weak forces governing GLP-1 oligomer stability

Anyah Settle, Rahul Mishra, Ramesh Kumar Shanmugam et al. Apr 01, 2026 pp. 111223 10.1016/j.jbc.2026.111223

SLC52A1 is a neofunctionalized primate urate transporter enabling intestinal urate secretion

Syunsuke Yamamoto, Katsuhisa Inoue, Tomoya Yasujima et al. Apr 01, 2026 pp. 111310 10.1016/j.jbc.2026.111310

Forces that shape the transcriptome: Linking cellular mechanosensing to mRNA splicing

Pavel Simara, Cristina Mazzotti, Gokula Narayanan et al. Apr 01, 2026 pp. 111352 10.1016/j.jbc.2026.111352

Structural basis of RNA polymerase II transcription on the histone H3–H4 octasome

Cheng-Han Ho, Kayo Nozawa, Masahiro Nishimura et al. Apr 01, 2026 pp. 111340 10.1016/j.jbc.2026.111340

The SWI/SNF complex in tumor metabolism: Mechanisms and therapeutic implications

Xuan-Hao Pan, Jian Wang, Jing Su et al. Apr 01, 2026 pp. 111342 10.1016/j.jbc.2026.111342

Plasticity in the structure and assembly of proteasomes

Alana H. Chang, Swarnab Sengupta, Robert J. Tomko Apr 01, 2026 pp. 111334 10.1016/j.jbc.2026.111334

Mechanisms of DNA methyltransferase 3A1-mediated DNA methylation of nucleosomes

Ethan Ward, Drew McDonald, Tyler Holl et al. Apr 01, 2026 pp. 111303 10.1016/j.jbc.2026.111303

Structure of Acinetobacter baumannii cytochrome bo3 ubiquinol oxidase

Quan Li, Rui Hao, Jiapeng Zhu et al. Apr 01, 2026 pp. 111324 10.1016/j.jbc.2026.111324

Altered benzo[a]pyrene adduct formation in nucleosomes establishes distinct mutational patterns in lung cancer

Benjamin Morledge-Hampton, Markus Lindberg, Erik Larsson et al. Apr 01, 2026 pp. 111291 10.1016/j.jbc.2026.111291

Mechanistic insights into Na+ pumping by KR2: Distinct roles of Asp102 and Asn112 coupled with retinal distortion in two O intermediates

Sahoko Tomida, Rei Abe-Yoshizumi, Akimori Wada et al. Apr 01, 2026 pp. 111313 10.1016/j.jbc.2026.111313

Differential activity of nonmuscle myosin IIA and IIB isoforms generates a dynamic actomyosin network in a concentration-dependent manner

Saurabh Shrivastva, Debojit Chanda, Farmaanullah Ansari et al. Apr 01, 2026 pp. 111275 10.1016/j.jbc.2026.111275

Structural insights into specific recognition of the histone variant H2A.Z by the YL1 subunit of SRCAP chromatin-remodeling complex

Wansen Tan, Yue Liu, Jingjun Hong Apr 01, 2026 pp. 111294 10.1016/j.jbc.2026.111294

Deficient mitochondrial tRNA modifications arising from TRMU mutation led to the liver-specific failure

Xiao He, Qinghai Zhang, Chao Chen et al. Apr 01, 2026 pp. 111168 10.1016/j.jbc.2026.111168

Human pumilio proteins use fuzzy multivalent hydrophobic interactions to recruit the CCR4–NOT deadenylase complex to repress mRNAs

Elise B. Dunshee, Brenna A. Saladin, David J. Turner et al. Apr 01, 2026 pp. 111281 10.1016/j.jbc.2026.111281

G protein Gαq subunits engage targets in the nucleus involved in chromatin remodeling and gene expression

Joseph Loomis, Naincy Chandan, Michael Burroughs et al. Apr 01, 2026 pp. 111322 10.1016/j.jbc.2026.111322

Sialic acids modulate immune responses in cancer: Therapeutic opportunities

Eleanor E. Bashian, James C. Paulson, Peng Wu Apr 01, 2026 pp. 111245 10.1016/j.jbc.2026.111245

PA14 domain of glycosyltransferase B4GALNT3 is a lectin that binds to sulfated glycan ligands

Yuko Tokoro, Takahiro Yamasaki, Hiroaki Tateno et al. Apr 01, 2026 pp. 111328 10.1016/j.jbc.2026.111328