Journal of Biological Chemistry

The intrinsically disordered region of the human parathyroid hormone controls functional amyloid properties

Shubhra Sachan, Twinkle Bhatia, Monika Baumann et al. Apr 01, 2026 pp. 111295 10.1016/j.jbc.2026.111295

G6PD facilitates axon regeneration via clathrin-mediated endocytosis

Chunyi Jiang, Xinyi Liu, Hui Li et al. Apr 01, 2026 pp. 111345 10.1016/j.jbc.2026.111345

Identification of a distinct family of polyphosphate kinases relevant to energy homeostasis in Crenarchaeota

Svenja Höfmann, Roman Kogay, Christian Schmerling et al. Apr 01, 2026 pp. 111283 10.1016/j.jbc.2026.111283

TOP1 and TOP2 complementarily maintain DNA replication fork progression in vertebrates

Koyuki Umemura, Masato Ooka, Miku Sojo et al. Apr 01, 2026 pp. 111339 10.1016/j.jbc.2026.111339

An enhancement of extrachromosomal circular DNA enrichment and amplification to address the extremely low overlap between replicates

Charles M. Burnham, Alongkorn Kurilung, Visanu Wanchai et al. Apr 01, 2026 pp. 111302 10.1016/j.jbc.2026.111302

HuR-driven reversible mitochondrial shuttling buffers cytosolic miRNA levels in hepatic cells

Saikat Banerjee, Sourav Hom Choudhury, Susanta Chatterjee et al. Apr 01, 2026 pp. 111255 10.1016/j.jbc.2026.111255

Dynamic assessment of the allocation of copper to cytochrome c oxidase using size-exclusion chromatography (SEC) combined with inductively coupled plasma mass spectrometry (ICP-MS)

Dina Secic, Megan E. Bischoff, Lucas Schmidt et al. Apr 01, 2026 pp. 111278 10.1016/j.jbc.2026.111278

Attenuated lamin A–prohibitin2 interaction leads to mitochondrial dysfunction in LMNA 289 A>G–mediated dilated cardiomyopathy

Subhradip Nath, Debasish Prusty, Sk Ramiz Islam et al. Apr 01, 2026 pp. 111274 10.1016/j.jbc.2026.111274

Transcriptome-guided discovery and active-site gatekeeper engineering of a Viola arcuata asparaginyl ligase with superior catalytic performance

Qiongyan Zou, Yujiao Yan, Xinglei Zou et al. Apr 01, 2026 pp. 111301 10.1016/j.jbc.2026.111301

Apolipoprotein M: Structural insights, functional roles, and therapeutic approaches in vascular disease

Tim F. Dorweiler, Timothy Hla Apr 01, 2026 pp. 111335 10.1016/j.jbc.2026.111335

Identification and characterization of inhibitors of the tuberculosis phosphatase PstP

Chase Riedel, Jeremy Rahkola, Matthew Reichlen et al. Apr 01, 2026 pp. 111316 10.1016/j.jbc.2026.111316

Structural insights into glycoside hydrolase family 1 β-glucosidase: Selective oligosaccharide hydrolysis, synthesis, and product profiling

Chih-Chieh Lin, Hiroya Uno, Chihaya Yamada et al. Apr 01, 2026 pp. 111293 10.1016/j.jbc.2026.111293

Aspartate treatment ameliorates metabolic dysfunction-associated fatty liver disease through upregulation of CBS and suppression of ferroptosis

Jie Zhang, Shihua Lin, Tiantian Zhang et al. Apr 01, 2026 pp. 111318 10.1016/j.jbc.2026.111318

A characterization of recombinant Arabidopsis FRIABLE1 (FRB1) reveals robust rhamnogalacturonan-I rhamnosyltransferase activity and critical catalytic residues

Kayleigh J. Robichaux, Madison N. Blea, Robert A. Amos et al. Apr 01, 2026 pp. 111305 10.1016/j.jbc.2026.111305

Rab5 nucleotide binding promotes oxidative metabolism to fuel hepatocellular carcinoma cell proliferation

Kelly O. Otakhor, Mohd Ali Abbas Zaidi, Rebecca E. Oberley-Deegan et al. Apr 01, 2026 pp. 111321 10.1016/j.jbc.2026.111321

The RNA methyltransferase NSUN2 catalyzes 5-methylcytosine (m5C) on IL1B mRNA to promote transcript stability

Jiayun Wang, Lingyan Yan, Rong Jia et al. Apr 01, 2026 pp. 111290 10.1016/j.jbc.2026.111290

Elevated neuraminidase potentiates lung inflammation through facilitating integrin β2-mediated adhesion and immune responses of neutrophils

Lulu Huang, Amy Tang, Hui Zhong et al. Apr 01, 2026 pp. 111311 10.1016/j.jbc.2026.111311

The protein phosphatase 2A-B56α complex regulates N-Myc degradation in neuroblastoma

Brian D. Tran, Irene Peris, Ethan Wurman et al. Apr 01, 2026 pp. 111298 10.1016/j.jbc.2026.111298

Ganglioside GM2 induces epithelial–mesenchymal transition (EMT) in cancer cells in a MEK/ERK/Egr1-dependent transcriptional program

Elora Khamrui, Sounak Banerjee, Subha Ray et al. Apr 01, 2026 pp. 111306 10.1016/j.jbc.2026.111306

Mapping the temporality and structural impacts of modifications in Escherichia coli tRNAs

Marcel-Joseph Yared, Carine Chagneau, Pierre Barraud Apr 01, 2026 pp. 111337 10.1016/j.jbc.2026.111337

GPCR-selective effects of endocytosis on cellular signaling through the cAMP/PKA cascade

Emily E. Blythe, Rita R. Fagan, Mark von Zastrow Apr 01, 2026 pp. 111253 10.1016/j.jbc.2026.111253

The Hsp40 cochaperone DNAJC7 regulates polyglutamine aggregation and exhibits context-dependent effects on polyglycine aggregation

Biswarathan Ramani, Kean Ehsani, Martin Kampmann Apr 01, 2026 pp. 111292 10.1016/j.jbc.2026.111292

AKAP2 is required for assembly of cytoskeletal signaling complexes that promote growth and metastasis of triple-negative breast cancer

Kacey J. Rosenthal, Pamela Felix-Sanchez, Katherine Forbush et al. Apr 01, 2026 pp. 111329 10.1016/j.jbc.2026.111329

Oligomer-dependent and oligomer-independent pathogenesis of muscular dystrophy-associated mutations within the penta-EF-hand domain of calpain-3

Chihiro Hisatsune, Fumiko Shinkai-Ouchi, Shoji Hata et al. Apr 01, 2026 pp. 111277 10.1016/j.jbc.2026.111277

Evidence that non-cognate proteinogenic amino acids generate immunogenic neoepitopes

Kenneth J. Rodgers Apr 01, 2026 pp. 111349 10.1016/j.jbc.2026.111349