Journal of Biological Chemistry

Structural basis for inhibition of the voltage-gated sodium channel NaV1.7 by the tarantula toxin HWTX-I

Hang Wu, Wenxing Wang, Zhaotun Hu et al. Jun 01, 2026 pp. 113130 10.1016/j.jbc.2026.113130

Impact of salt concentration and free magnesium on human beta-cardiac myosin reveal important details about the conserved mechanochemical mechanism

Jinghua Ge, Michael R. Ebert, Skylar M.L. Bodt et al. Jun 01, 2026 pp. 113114 10.1016/j.jbc.2026.113114

An inhibitor of GCN2 and the integrated stress response directly targets ZAK protein kinase to limit cytotoxicity

Jagannath Misra, Dan F. Spandau, Jonah Z. Vilseck et al. Jun 01, 2026 pp. 111482 10.1016/j.jbc.2026.111482

The role of phospho-ubiquitin in mitochondrial health and diseases

Kumar Suresh, Christopher Rainville, David E. Sterner et al. Jun 01, 2026 pp. 113128 10.1016/j.jbc.2026.113128

Variants in glycine decarboxylase activate catabolic mechanisms of mitochondrial energy metabolism in the brain

Alejandro Lopez-Ramirez, Andrew J. Worth, Ziyi (Lindsay) Wang et al. Jun 01, 2026 pp. 113098 10.1016/j.jbc.2026.113098

Alternative probe chemistries for single-molecule analysis of long noncoding RNA

Kalika R. Pai, Aimee M. Martin, Madison Kadrmas et al. Jun 01, 2026 pp. 111441 10.1016/j.jbc.2026.111441

A coherent structural picture of the interaction of Tau with tubulin provides a link to its aggregation

Benoît Gigant, Liza Ammar Khodja, Valérie Campanacci et al. Jun 01, 2026 pp. 113086 10.1016/j.jbc.2026.113086

A proximity-labeling map of PI5P4K phosphoinositide kinases interaction networks

Alicia Llorente, Gurpreet K. Arora, Ryan M. Loughran et al. Jun 01, 2026 pp. 113071 10.1016/j.jbc.2026.113071

Steroid receptor coactivators in immunity - From function to emerging translational opportunities

Yosef Gilad, David M. Lonard Jun 01, 2026 pp. 113087 10.1016/j.jbc.2026.113087

Correction: The necessity of multi-parameter normalization in cyanobacterial research: A case study of the PsbU in Synechocystis sp. PCC 6803 using CRISPRi

Maria Christine Veit, Ron Stauder, Yu Bai et al. Jun 01, 2026 pp. 111453 10.1016/j.jbc.2026.111453

Electrostatic tuning of the pyridoxal-5′-phosphate cofactor site defines pH dependence in type I cystathionine β-lyases

Yuanxiang Liu, Xin Li, Jianxun Li et al. Jun 01, 2026 pp. 111469 10.1016/j.jbc.2026.111469

Sustained β-catenin activation via GSK3 inhibition promotes direct fibroblast-to-cardiomyocyte reprogramming

Xinghua Wang, Iqra Anwar, Richard E. Pratt et al. Jun 01, 2026 pp. 111458 10.1016/j.jbc.2026.111458

The role of HIF-1α in innate immune mechanisms and autoimmunity: A double-edged sword

Martha L. Chapple, Arnaud Zaldumbide, Raphael R. Fagundes Jun 01, 2026 pp. 111429 10.1016/j.jbc.2026.111429

NS5 polymerase stimulates RNA duplex unwinding by the Orthoflavivirus NS3 helicase

Jamie J. Arnold, Shubeena Chib, Craig E. Cameron Jun 01, 2026 pp. 113118 10.1016/j.jbc.2026.113118

Lipid transfer proteins and PI4KIIα initiate nuclear p53-phosphoinositide signaling

Noah D. Carrillo, Mo Chen, Poorwa Awasthi et al. Jun 01, 2026 pp. 113123 10.1016/j.jbc.2026.113123

The tumor suppressor NDRG2 recruits protein phosphatase 2A to suppress STAT5 phosphorylation in adult T-cell leukemia/lymphoma

Tomonaga Ichikawa, Shingo Nakahata, Kazuya Shimoda et al. Jun 01, 2026 pp. 113080 10.1016/j.jbc.2026.113080

A thiadiazolylidene-morpholine compound inhibits Pseudomonas aeruginosa by destabilizing the thiamine monophosphate kinase thiL

Yingying Li, Jianqing Lin, Zara Chung et al. Jun 01, 2026 pp. 113112 10.1016/j.jbc.2026.113112

A noncanonical RNA polymerase assembly pathway in Bacillus subtilis: α Dimer associates with either β or β′ before forming the core enzyme

Aniruddha Tewary, Anushka Chakraborty, Runa Sur et al. Jun 01, 2026 pp. 111478 10.1016/j.jbc.2026.111478

Molecular analysis of a new patient COX15 mutation provides insight into the etiology of fatal infantile cardioencephalopathy

Jayda A. Carroll-Deaton, Iryna Bohovych, Faith T. Emetu et al. Jun 01, 2026 pp. 111475 10.1016/j.jbc.2026.111475

Correction: Acylation of Lysine 983 Is Sufficient for Toxin Activity of Bordetella pertussis Adenylate Cyclase

Tümay Basar, Vladimír Havlíček, Silvia Bezoušková et al. Jun 01, 2026 pp. 111454 10.1016/j.jbc.2026.111454

A tungsten-specific maturation pathway governs cofactor assembly of a CO2-reducing formate dehydrogenase in Methylorubrum extorquens

Uyen Thu Phan, Yong Hwan Kim Jun 01, 2026 pp. 111483 10.1016/j.jbc.2026.111483

Rab8 and TNPO1 function as the ciliary transport adapters for GPCRs

Divyanshu Mahajan, Viswanadh Madugula, Hui Min Chia et al. Jun 01, 2026 pp. 112202 10.1016/j.jbc.2026.112202

Receptor-substrate competition for the TonB homolog FusB suggests a model for ferredoxin import

Marta Wojnowska, Victor Flores, Tamas Yelland et al. Jun 01, 2026 pp. 113121 10.1016/j.jbc.2026.113121

Structure-guided discovery of non-catechol dopamine D1 receptor ligands with biased agonism and antagonism

Yang Zhou, William C. Wetsel, Alem W. Kahsai et al. Jun 01, 2026 pp. 113076 10.1016/j.jbc.2026.113076

Functional evaluation of TRPC6 missense variants in cancer patients via molecular docking analysis compared with patch Clamp electrophysiology

Ying Wu, Xiaojing Sun, Joseph S. Reddy et al. Jun 01, 2026 pp. 113124 10.1016/j.jbc.2026.113124