PLoS ONE
Articles in this Issue
Impact of social determinants of health on obesity among American Indian and Alaska Native young adults
We examined the prevalence of obesity among American Indian and Alaska Native (AIAN) young adults and to investigate the association between key social determinants of health (SDOH) and higher body ma...
Power production and area usage of offshore wind and the relationship with available energy in the atmosphere
This paper presents an analysis of the area dependency of power and capacity density of wind farms, based on derivations of the available energy in the atmosphere and data on the power production of e...
LSTM-conformal forecasting-based bitcoin forecasting method for enhancing reliability
Cryptocurrency is a new type of asset that has emerged with the advancement of financial technology, creating significant opportunities for research. bitcoin is the most valuable cryptocurrency and ho...
Research on the supply-demand balance evaluation and driving mechanism of community public service facilities
The configuration level of community-level public service facilities is an important indicator for assessing the completeness of the urban public service system, and its spatial equilibrium directly i...
Are people willing to take regular vaccinations? A qualitative study among diverse ethnic groups in Hong Kong
Vaccine hesitancy is identified as one of the top ten global health threats by the World Health Organization. The emergence of new coronavirus variants and evidence of waning immunity offered by COVID...
Trends, levels, and projections of Head and Neck Cancer in China between 2000 and 2021: Findings from the Global Burden of Disease 2021
Head and neck cancer (HNC), a condition that is both disfiguring and potentially fatal, has become a critical public health challenge. This study seeks to evaluate the trends in HNC burden and predict...
Adipocyte-specific deletion of Dbc1 does not recapitulate healthy obesity phenotype but suggests regulation of inflammation signaling
The protein Deleted in Breast Cancer 1 (Dbc1) is an important regulator of various transcription factors and epigenetic modulators, significantly influencing metabolism, obesity, and aging-related pro...
Copy number variations in AMY2B gene and amylase activity in Balkan dog breeds
This study aims to estimate the number of AMY2B gene copies and measure serum amylase activity in several Balkan dog breeds. Additionally, it explores the relationship between these genetic and bioche...
Mechanistic insights into Alpha-Synuclein binding to P2RX7: A molecular dynamic and docking study
Alpha-synucleinopathies, characterized by extracellular alpha-synuclein (αSyn or SNCA) accumulation and aggregation, have been linked to neurological disorders including Parkinson’s disease and multip...
Resistance exercise combined with protein supplementation for skeletal muscle mass in people with pancreatic cancer undergoing neoadjuvant chemotherapy: Study protocol for the REBUILD trial
Background Pancreatic cancer patients’ prognosis may be limited by two conditions, cachexia and sarcopenia. Resistance exercise and protein supplementation are safe non-pharmacological strategies that...
The experiences of high-risk young adults with type 1 diabetes transitioning to real-time continuous glucose monitoring – A thematic analysis
Background Real-time continuous glucose monitoring (rtCGM) is now the standard care for people with type 1 diabetes. However, whilst its impact on glycaemic outcomes is well-documented, its psychosoci...
Moral decision-making is altered in patients with schizophrenia
Introduction Previous research suggests patients with schizophrenia have altered decision-making when presented with philosophical moral scenarios. However, not much is known about everyday moral deci...
Impact of COVID-19 on mucormycosis presentation and laboratory values: A comparative analysis
Background The COVID-19 pandemic has led to an alarming increase in mucormycosis coinfections and its rapid progression. The overlapping risk factors and symptoms between COVID-19 and mucormycosis fur...
The effect of unmet needs on the health-related Quality of life of family caregivers of cancer patients in South Korea
This study was conducted to explore the unmet needs and health-related quality of life (QOL) of family caregivers who support cancer patients, and to determine the impact of these unmet needs on their...
Widespread coral bleaching and mass mortality during the 2023–2024 marine heatwave in Little Cayman
The increased frequency and intensity of marine heatwaves (MHWs) induced by continued global warming are the greatest threat to tropical coral reefs, causing mass bleaching events and widespread morta...
A landscape analysis of psychedelic retreat organizations advertising online
Research into psychedelics’ clinical potential has corresponded to a growth in public interest and adult use. One common pathway to accessing psychedelics is through psychedelic retreats. While indivi...
Novel insights into rural spatial design: A bio-behavioral study employing eye-tracking and electrocardiography measures
In order to objectively assess the effectiveness of rural space design on the affective dimension, this study utilized eye-tracking and electrocardiogram (ECG) monitoring techniques to quantify users’...
Bacterial profile, treatment outcomes, and determinants among adult patients with musculoskeletal infections admitted to Jimma Medical Center: A prospective observational study
Background The epidemiological characteristics of musculoskeletal infections are constantly evolving. Despite the significant burden of musculoskeletal infections in sub-Saharan Africa, there is a sca...
Exploratory outcomes of the DHA WIN randomized controlled trial: Supplementing women with docosahexaenoic acid did not reduce the impact of neoadjuvant breast cancer chemotherapy on quality of life or exercise behaviour
Supplementation of omega-3 (n-3) polyunsaturated fatty acids has been associated with reduced side effects and improved quality of life (QoL) in breast cancer patients receiving chemotherapy. The curr...
Family caregivers’ experience of caring for patients undergoing hemodialysis: A qualitative study at Muhimbili National Hospital in Dar es Salaam, Tanzania
Background The number of patients with chronic kidney disease requiring hemodialysis services is growing in Tanzania. Considering patients undergoing hemodialysis are outpatients, family caregivers fi...
Influence of abiotic factors in Calliphoridae and Mesembrinellidae (Insecta: Diptera) entomofauna in the Jardim Botânico do Rio De Janeiro, Brazil
Diptera are one of the four megadiverse insect orders, with great environmental, ecological, forensic and medical-sanitary relevance. The Jardim Botânico do Rio de Janeiro, located in an urban area of...
“The child of your fellow is your child”: Building on existing protective norms to engage men as caregivers; qualitative findings from an exploratory evaluation of an edutainment intervention to prevent age-disparate transactional sex
Evidence on the importance of engaging men in preventing violence against women and girls has increased over the past decade, yet efforts often focus on men as partners rather than caregivers. This pa...
Child undernutrition is associated with maternal mental health and other sociodemographic factors in low-income settings in Dhaka, Bangladesh
Background Maternal mental health and other underlying factors might affect a child’s nutritional status. This study assesses child undernutrition and its associated characteristics, including materna...
Inhibition of cytotoxic fibril formation of α-synuclein and human insulin by Silymarin from the Silybum marianum
Silymarin (SIL), the extract obtained from the seeds of milk thistle (Silybum marianum), contains several flavonolignans with a broad range of therapeutic properties such as antioxidant, anti-inflamma...
Multi-channel pricing strategies for pharmaceutical supply chains considering channel power and price competition
In the context of the reality that pharmaceutical manufacturers and retailers are simultaneously opening online sales channels, three different multi-channel pharmaceutical supply chain game models we...