PLoS ONE
Articles in this Issue
Evaluating how different balancing data techniques impact on prediction of premature birth using machine learning models
Premature birth can be defined as birth before 37 weeks of gestation, which is a significant global health issue, being the main cause for neonatal deaths. In this work, we evaluate machine learning m...
Computational network biology analysis revealed COVID-19 severity markers: Molecular interplay between HLA-II with CIITA
COVID-19, severe acute respiratory syndrome coronavirus 2, rapidly spread worldwide. Severe and critical patients are expected to rapidly deteriorate. Although several studies have attempted to uncove...
Analysis on the potential of Pennisetum hydridum for phytoremediation of Cd-polluted soil fertilized by worm castings
Soil heavy metal pollution including Cd, is the main factor that causes the decline of ecological environment quality, the excessive content in crops and the harm to human health. Phytoremediation is...
Evaluation of statistical methods applied in theses and dissertations in an Open, Distance and e-Learning University
The appropriate application of research methods and statistical analyses used in the studies directly affects the quality of scientific studies. Due to the possibility of employing an incorrect statis...
Editorial Note: Prolonged immune alteration following resolution of acute inflammation in humans
Ictal cardiovascular autonomic dysfunction during focal seizures induced by direct electrical stimulation: An observational study research protocol
Introduction Autonomic symptoms, such as changes in heart rate, blood pressure, or respiration often accompany epileptic seizures and, in some cases, may be life threatening or even contribute to sudd...
Cytomegalovirus host receptor expression in the human fetal inner ear
Fetal infection with human cytomegalovirus (hCMV) can cause sensorineural hearing loss and vestibular impairment, yet its pathogenesis remains unclear. This study aims to identify potential target cel...
Development of label-free cell tracking for discrimination of the heterogeneous mesenchymal migration
Image-based cell phenotyping is fundamental in both cell biology and medicine. As cells are dynamic systems, phenotyping based on static data is complemented by dynamic data extracted from time-depend...
Measuring metabolic energy expenditure with short duration walking tests for individuals with lower limb amputation
Introduction Metabolic assessment of prosthetic gait is useful when comparing devices, interventions, or populations. However, the standard requirement to walk continuously for six minutes or more to...
Advancing methods for comparative urban research: A city-centric protocol and longitudinal dataset for US metropolitan statistical areas
Comparative urban research in the USA has an unacknowledged data and methodological problem at the metropolitan scale, rooted in geographic and definitional boundary changes of urban areas across time...
UFM: Unified feature matching pre-training with multi-modal image assistants
Image feature matching, a foundational task in computer vision, remains challenging for multimodal image applications, often necessitating intricate training on specific datasets. In this paper, we in...
Aerobic exercise and brain structure among military service members and Veterans with varying histories of mild traumatic brain injury: A LIMBIC-CENC exploratory investigation
Objectives To explore associations of recent moderate-to-vigorous aerobic exercise (MVAE) participation and lifetime mild traumatic brain injury (mTBI) history with measures of brain gray matter volum...
The perception of eye contact is associated with men’s need to belong, self-esteem, and loneliness
The present study (N = 367) investigated the association of the cone of direct gaze (CoDG; a range within which slightly averted gaze is accepted as direct gaze) width with the need to belong (NTB) a...
Extended spectrum β-lactamase (ESβL)-producing E. coli causing urinary tract infection among pregnant women and pediatric patients in public hospitals in northern Jordan
Background Urinary tract infections (UTI’s) imply the invasion and multiplication of bacteria in the individual’s urinary tract, the incidence of UTI’s is mainly determined by sex and age being the hi...
Development of a health index for stranded marine tetrapods
This study presents the development and validation of a Health Index (HI) to assess the overall health of stranded marine tetrapods (seabirds, sea turtles, and marine mammals). The HI is based on para...
Prevalence and anatomical significance of the persistent median artery: A cadaveric study
Purpose The median artery is the initial, yet transient, vascular supply to the palm originating from the brachial artery during development. This artery generally regresses as radial and ulnar arteri...
Ex ante economic impact assessment of the 3R-gene potato in Kenya
Potato late-blight disease is as a major constraint to potato production in Kenya. The use of fungicides to control the disease is limited by the practice of delaying application until the symptoms ar...
Identification method and application of order parameters for organizational systems considering time-series values: A case study on high-quality development in China’s regional manufacturing industry
The transition from disorder to order in the evolution of organizational systems is driven by the identification of key order parameters, which serve as critical determinants of this shift and the pri...
Promoting Pro-environmental Beliefs and Behaviour: Choose-Your-Own Story Futuristic Climate Game
How can we address climate scepticism and increase public support for ambitious pro-environmental policies? This study investigates the potential of future-oriented perspective taking, using an innova...
Exposure to circadian disrupting environment and high-fat diet during pregnancy and lactation alter reproductive competence and lipid profiles of liver, mammary, plasma and milk of ICR mice
This study’s objective was to determine the effects of pre-pregnancy obesity induced by a high-fat diet and exposure to circadian-disrupting light-dark phase shifts on birth littler size, pup survival...
Experimental study on anti-drift shield curtain device for soybean (Glycine max)-maize (Zeal mays) strip intercropping weed sprayers
Soybean-maize strip intercropping is an important method to increase soybean oil self-sufficiency and promote sustainable agricultural development, which has rapidly developed in China in recent years...
SMND-309 activates Nrf2 signaling to alleviate acetaminophen-induced hepatotoxicity and oxidative stress
Background Acetaminophen (APAP) can be used for pain relief and fever alleviation, the overdose of which, however, may lead to the accumulation of N-acetyl-p-benzoquinone imine (NAPQI), inducing oxida...
Hyers Ulam stability and bifurcation control of leptospirosis disease dynamics and preventations: Modeling with singular and non-singular kernels
Due to its various uses, the dynamical system is a significant research area in the field of mathematical biology. The model is first developed by applying the usual derivative with combined recovery...
Comparison of CMIP6 GCMs historical precipitation with measured precipitation over Pakistan
Comparison of Coupled Model Intercomparison Project Phase 6 (CMIP6) General Circulation Models (GCMs) with observations under different climatic conditions is necessary to determine their respective s...
Adherence to the current guidelines on antibiotic prescription among dental practitioners: A national survey
Background The global emergence and spread of antibiotic resistance jeopardise health-care advances and life expectancy. Following the latest antibiotic guidelines is crucial to combat this issue. The...