PLoS ONE
Articles in this Issue
Impact of thermoneutral acclimation on a murine model of polymicrobial peritonitis
To examine the effects of ambient temperature on the reproducibility and translation of a murine sepsis model, we hypothesized that acclimation of mice in temperatures within their thermoneutral zone...
Influence of study shift on the interrelationships among chronobiological factors, health practices, and anthropometry in adolescents
The mismatch between chronobiological predispositions and social demands makes it difficult for adolescents with an evening chronotype to maintain healthy habits. This study aimed to explore the inter...
FIAEPI-KD: A novel knowledge distillation approach for precise detection of missing insulators in transmission lines
Ensuring transmission line safety is crucial. Detecting insulator defects is a key task. UAV-based insulator detection faces challenges: complex backgrounds, scale variations, and high computational c...
Analysis of the emergency response capacity of nursing staff for public health emergencies and the influencing factors: A cross-sectional study in China
Background The frequent occurrence of public health emergencies poses a serious challenge to the emergency response capacity of Chinese nurses. However, nurses still suffer from insufficient emergency...
Housing prices in China follow Zipf’s law
This study verifies that housing prices in China follow Zipf’s law by analyzing the average housing prices in 200 Chinese cities between 2015 and 2023. The Kolmogorov-Smirnov (KS) test further support...
Clinicopathological comparison of eccrine poroma and porocarcinoma: Ki-67 index is not a decisive factor
Background Eccrine poroma (EP) and porocarcinoma (EPC) arise from the intraepidermal part of the sweat gland. Clinically they resemble each other and cannot be distinguished without histopathological...
Psychological factors associated with sensory processing sensitivity in caregiving contexts: A protocol for a systematic review and meta-analysis
Background Caregiving, in both professional and informal settings, is a stressful role linked to burnout, anxiety and other negative mental health outcomes. Both environmental factors, such as perceiv...
Intertwined risk factors of mental health and cardiovascular diseases: A cross-sectional survey in Godawari Municipality of Far-western Nepal
Introduction Cardiovascular diseases (CVDs) are the leading global cause of death, whereas mental disorders account for one-third of all global disabilities. Despite clear availabl...
Scoping review on regulation, implementation and postmarket surveillance of medical devices
Background Regulation and postmarket surveillance of medical devices have been criticized for being too lenient as compared to drug regulation and postmarket surveillance. Little is known about the fa...
Phenome-wide association study and functional annotation of hemoglobin A1c-associated variants in African populations
Background Glycated hemoglobin (HbA1c) measures the average blood sugar level over the past three months. As a vital biomarker of blood glucose levels, it is used to diagnose Type-2 diabetes mellitus...
Gait assessment using a 2D video-based motion analysis app in healthy subjects and subjects with lower limb amputation – A pilot study
Introduction Although three-dimensional marker-based motion analysis is the gold standard for biomechanical investigations, it is time-consuming and cost-intensive. The conjunction of monocular video...
Role of blood Krebs von Lungen-6 in predicting acute exacerbation in patients with idiopathic pulmonary fibrosis
Background This study evaluated the role of blood Krebs von den Lungen-6 (KL-6) in predicting acute exacerbation (AE) in patients with idiopathic pulmonary fibrosis (IPF). Methods From April 2018 to...
Optimization of non-smooth functions via differentiable surrogates
Mathematical optimization is fundamental across many scientific and engineering applications. While data-driven models like gradient boosting and random forests excel at prediction tasks, they often l...
GDFGAT: Graph attention network based on feature difference weight assignment for telecom fraud detection
In recent years, the number of telecom frauds has increased significantly, causing substantial losses to people’s daily lives. With technological advancements, telecom fraud methods have also become m...
Antimicrobial-resistance of Escherichia coli in dogs and cats: A scoping review
Pathogenic Escherichia coli causes a range of clinical manifestations in dogs and cats, and the use of antimicrobials in pets is associated with the risk of antimicrobial resistance (AMR). Pets contri...
Identifying genes and traits associated with pre-eclampsia using summary statistics
The occurrence and development of pre-eclampsia (PE) is closely related to genetics. However, multi-omics analysis does not provide sufficient evidence to define significant genes. Therefore, we aimed...
Numerical simulation study on optimization of key technical parameters of unpowered dust removal system in a gas-solid two-phase flow field
Based on the engineering background of the Huaibei Coal Preparation Plant in Anhui Province, China, this study aims to effectively mitigate dust pollution during the blanking process at coal transfer...
Schistosoma mansoni infection causes consistent changes to the fecal bacterial microbiota of mice across and within sites
Eggs of Schistosoma mansoni are produced by adult female worms in mesenteries of infected hosts. Eggs can cross the intestinal barrier and form granulomas in the tissue or breach and exit the host thr...
T7 RNA polymerase-based gene expression from a transcriptionally silent rDNA spacer in the endosymbiont-harboring trypanosomatid Angomonas deanei
Eukaryotic life has been shaped fundamentally by the integration of bacterial endosymbionts. The trypanosomatid Angomonas deanei that contains a β-proteobacteri...
Deep learning reconstruction of free-breathing, diffusion-weighted imaging of the liver: A comparison with conventional free-breathing acquisition
This study aimed to compare image quality and solid focal liver lesion (FLL) assessments between free-breathing, diffusion-weighted imaging using deep learning reconstruction (FB-DL-DWI) and conventio...
A framework for identifying calcium accumulation problem in cropland: Integrating field surveys, legacy soil map, and machine learning models
The calcium accumulation problem (CAP) in cinnamon soil regions of northern China significantly impacts crop yields. Identifying and mitigating CAP is crucial for improving soil quality and agricultur...
Educational video combined with augmented clinical support to improve CPAP use in patients with obstructive sleep apnea-hypopnea syndrome: A randomized controlled trial protocol
Background Poor patient adherence to continuous positive airway pressure (CPAP) remains a common challenging issue and a major cause of treatment failure in patients with obstructive sleep apnea-hypop...
Thymoquinone loaded on chitosan nanoparticles alleviated the consequences of cryptosporidiosis infection in a murine model: Evidence from parasitological, histopathological, immunohistochemical, and immunological studies
Background Cryptosporidiosis, a parasitic zoonosis caused by the genus Cryptosporidium (C.), currently lacks a vaccine or fully effective treatment. Nitazoxanide (NTZ), the only medication approved by...
EODA: A three-stage efficient outlier detection approach using Boruta-RF feature selection and enhanced KNN-based clustering algorithm
Outlier detection is essential for identifying unusual patterns or observations that significantly deviate from the normal behavior of a dataset. With the rapid growth of data science, the prevalence...
Constraining the population size estimates of the pre-Columbian Casarabe Culture of Amazonian Bolivia
The capacity of Amazonian environments to support large indigenous societies prior to European Contact has long been a contentious area of debate, particularly in regions where pre-Columbian cultures...