PLoS ONE
Articles in this Issue
Comprehensive profiling of circRNAs reveals stimulus-specific networks and core regulators of cellular senescence
Cellular senescence, a hallmark of aging and age-related disorders, is characterized by irreversible cell cycle arrest and profound molecular alterations. Although previous transcriptomic studies have...
Distinct mutational landscapes and phylogenomic insights of the SARS-CoV-2 delta variant in Pakistan and India: Regional evolution, novel mutations, and epidemiological implications
Delta SARS-CoV-2 triggered a devastating wave of COVID-19 in India, infecting approximately 26% of the population (~357 million people) within four months, with ~0.4 million new cases per day, and aro...
Long-term clinical outcomes of endoscopic retrograde cholangiopancreatography for pancreatic duct stone treatment in children with chronic pancreatitis
Background Evidence on long-term outcomes of endoscopic retrograde cholangiopancreatography (ERCP) for pancreatic duct stones (PDS) in children with chronic pancreatitis (CP) remai...
Perceptions of assisted reproductive technologies in wildlife conservation: Public expectations and ethical implications across three EU countries
This paper examines public perceptions of Assisted Reproductive Technologies (ART) in wildlife conservation across three European countries: Czechia, Germany, and Italy. In the context of ongoing biod...
Analysis of the correlation between vaginal microbiota and high-risk human papillomavirus infection and cervical lesions
The aim of this study was to evaluate changes in the vaginal microbiota and biomarkers among high-risk human papillomavirus (hrHPV)-positive women, those with hrHPV accompanied by mucositis, and patie...
Magnitude, resistance profiles, and risk factors of intestinal parasites and enteric bacteria among food handlers in West Guji Zone, Ethiopia
Introduction Despite food handlers’ crucial role in pathogen transmission, current data on intestinal parasites and antimicrobial susceptibility and resistance patterns of enteric...
Body fat percentage is independently associated with lower pulmonary function in Korean never-smokers: A cross-sectional analysis of 33,748 adults
Background The relationship between obesity and pulmonary function is difficult to interpret using body mass index (BMI) alone because BMI cannot distinguish adiposity from lean ma...
Augmented reality for advanced prosthetic training in non-amputees
Prosthetic abandonment is highly prevalent among upper extremity amputees (UEA), partly due to lack of engaging and motivating training to use their devices. Augmented reality (AR) systems can be used...
Discriminant spectrogram local descriptors for electrocardiography biometric authentication
In recent years, Electrocardiogram (ECG) biometric authentication has emerged as a hot topic in biometrics research due to its unique advantages including intrinsic aliveness characteristics and conve...
Smartwatch-based detection of loss of pulse
We present a framework and a novel dataset for detecting loss of pulse cases using a smartwatch. Our methodology for gathering data involves inducing controlled pulse loss in the forearm within a clin...
Distinguishing post-COVID from long-COVID in adults: Development and validation of a biomarker signature using targeted proteomics and machine learning in a cross-sectional observational study
Background COVID-19 can have diverse clinical manifestations, ranging from asymptomatic infection to critical illness with multiorgan involvement. While many patients recover fully...
Ethnopharmocological study of medicinal plants used for treatment of skin diseases by herbalists in Northwestern region of Algeria
Background Skin disease is a major public health concern worldwide, particularly in developing countries. Despite the rich diversity of medicinal plants and strong traditional heal...
Point cloud generation adversarial network based on self-attention and curvature
As a mainstream form of 3D data, point clouds are widely used in computer vision for tasks such as segmentation, classification, and target detection due to their simple representation method and high...
MRI differentiation of usual type endocervical adenocarcinoma and cervical squamous cell carcinoma
Objectives To evaluate the magnetic resonance imaging (MRI) features that may help differentiate usual-type endocervical adenocarcinoma (UEA) from cervical squamous cell carcinoma...
Serum BDNF levels as a potential prognostic marker for functional recovery in stroke: Preliminary findings from a prospective observational study
Brain-derived neurotrophic factor (BDNF) crosses the blood-brain barrier and may serve as a marker of neuroplasticity. This study evaluated whether serum levels of mature BDNF, proBDNF, and matrix met...
Does the regulatory quality matter in the relationship between climate finance and inclusive growth in Africa?
This study scrutinizes the effect of climate finance on inclusive growth in Africa. It further explores how regulatory quality dynamics impact the connection between climate finance and Africa’s inclu...
Three-dimensional evaluation of soft tissue contour changes after premolar extraction with and without alveolar ridge preservation: A prospective observational study
Background This prospective observational study evaluated three-dimensional soft tissue contour changes over a 90-day healing period following bilateral premolar extractions, with...
Factors accelerating time to death among persons with Tuberculosis in Western India: Evidence from a community-based retrospective death audit
Introduction Tuberculosis (TB) remains a leading cause of death globally. India aims to eliminate TB by 2025; however, persistently high mortality rates suggest critical failures i...
Correction: Global burden of cardiovascular disease mortality attributable to secondhand smoke, 1990–2019: Systematic analysis of the Global Burden of Disease Study 2019
Using virtual reality hypnosis during stem cell transplant for patients in hematology: A protocol for a feasibility randomized study
Background Stem cell transplantation is a highly stressful treatment for hematological cancer patients, negatively impacting their quality of life. Hypnosis has proven effective in...
Building bridges for empowerment and informed decision-making: A qualitative study of midwives’ reflections on how to optimise contraceptive counselling for immigrant women in Sweden
Background Sweden’s National Strategy for Sexual and Reproductive Health and Rights (SRHR) emphasises equitable access to contraception and abortion services. Despite this, immigra...
Protective effect of cannabinoid type II receptor ligand on bleomycin-induced pulmonary fibrosis in mice
This study aimed to investigate the protective effects of the CB2R ligand compound COCA (N-(3-chloro-2-methylphenyl)-5-(4-hydroxyphenyl)-1,2-oxazole-3-carboxamide) against bleomycin (BLM)-induced pulm...
Dapagliflozin mitigates myocardial inflammation and metabolic stress in heart failure through STAT1 inhibition: Evidence from multi-omics analyses and experimental exploration
Background Heart failure (HF) is a global health challenge with high morbidity and mortality. While dapagliflozin (DAPA), a sodium–glucose cotransporter 2 inhibitor, has proven cli...
Statin prescribing patterns in cardiovascular risk management among outpatients with type 2 diabetes: Real-world practices at a Vietnamese general hospital
Objective This study aimed to evaluate the current prescribing patterns of statin therapy among outpatients with type 2 diabetes at Friendship Hospital, with a focus on alignment b...
Comparison of the 24-Style Tai Chi intervention based on various promotion approaches on college students’ mental health: A randomized controlled trial
Background The escalating pace of academic pressures and social life have intensified mental health challenges among college students, including widespread anxiety and depression....