PLoS ONE
Articles in this Issue
Development & validation of a health awareness booklet: “Reproductive health schemes for tribal women of Jharkhand” a study protocol
In India, women of reproductive age constitute of 22.2% of the total population. In tribal areas there are disparity in maternal health care utilization, lack of accessibility to safe menstrual health...
DNMT3A facilitates breast cancer progression via regulating ADAMTS8 mediated EGFR-MEK-ERK activation
ADAMTS8 inactivation by epigenetic modifications has been reported in various tumors, and the dysregulation of ADAMTS8 expression is associated with poor clinical outcomes, cancer cell invasion, and m...
Needs assessment for master of nursing program among Kenyan nurses
Background Nurses comprise the dominant cadre of healthcare workers yet there remains an acute shortage of nurses globally with Africa most affected. However, access to higher nursing education in sub...
Quantification of soil inorganic carbon using sulfamic acid and gas chromatography
Carbon dioxide is the primary greenhouse gas emitted through human activities, and these emissions impact the carbon cycle for hundreds to thousands of years. As carbon dioxide removal strategies to a...
The health-related quality of life among survivors with post-COVID conditions in the United States
Background Even after a mild initial SARS-CoV-2 infection, a considerable proportion of patients experience long-lasting symptoms. However, there is scarce data on how post-COVID conditions (PCCs) are...
Unveiling the impact of high-involvement work practices on team creativity: Exploring the interplay of team reflexivity and work demand attributes
This study aims to investigate the association between high-involvement work practices (HIWPs) and team creative performance (TCP) in Pakistan’s hospitality industry. Moreover, the mediating role of t...
Emerging trends and disparities in cardiovascular, kidney, and diabetes-related mortality: A retrospective analysis of the wide-ranging online data for epidemiologic research database
Introduction Cardiovascular-kidney-metabolic (CKM) syndrome, driven by metabolic risk factors like obesity, type 2 diabetes (DM-2), chronic kidney disease (CKD), and cardiovascular disease (CVD), lead...
Short versus long cephalomedullary nails for intertrochanteric femur fractures: A meta-analysis of randomized controlled trials
Purpose We aim to evaluate the efficacy and safety of short cephalomedullary nails(CMN) versus long CMN in patients with intertrochanteric femur fractures(IFFs). Methods The PubMed, Web of Science,...
The psychometric properties of childhood physical and sexual abuse measures in two Canadian samples of youth and emerging adults
Introduction Child maltreatment is prevalent in Canada; how we measure it varies. The objective of the current study was to examine the psychometric properties of the Childhood Experiences of Violence...
The costs of wind energy permitting compliance actions for regulated bats in the US
The wind industry’s expansion in North America due to the need to provide clean energy is leading to increased regulatory concern for bats, particularly those that are endangered due to white-nose syn...
Luminescence properties of Ge and Ge-Si structures on silicon-based microcavities
Utilizing laser etching technology under specific laser parameters (laser energy 250 mJ, repetition rate 1 Hz, pulse width 30 ns, spot diameter 150 µm), single-crystal silicon was etched, followed by...
Semisupervised adaptive learning models for IDH1 mutation status prediction
The mutation status of isocitrate dehydrogenase1 (IDH1) in glioma is critical information for the diagnosis, treatment, and prognosis. Accurately determining such information from MRI data has emerged...
Top-funded digital health companies offering lifestyle interventions for dementia prevention: Company overview and evidence analysis
Background and objective Dementia prevention has been recognized as a top priority by public health authorities due to the lack of a reversible cure. In this regard, digital dement...
A re-evaluation study and literature review on AD8 as a screening tool for dementia
Background The Eight-Item Informant Interview to Differentiate Aging and Dementia (AD8) was developed as a screening tool for dementia, with a cutoff score of 2 suggested by the initial study. However...
Perspectives of HPV vaccine decision-making among young adults: A qualitative systematic review and evidence synthesis
Background Despite the demonstrated safety and effectiveness of HPV vaccines in preventing HPV-related cancers, global vaccine coverage remains low. The suboptimal adolescent HPV vaccine coverage rate...
Navigating groundlessness: An interview study on dealing with ontological shock and existential distress following psychedelic experiences
Psychedelic induced mystical experiences have been largely assumed to drive the therapeutic effects of these substances, which may in part be mediated by changes in metaphysical beliefs. However, ther...
Comparison of healthcare costs of patients with COPD on maintenance inhaled therapies between 2011 and 2019 in Hungary using a nationwide database
Introduction and objectives Medical costs of patients with chronic obstructive pulmonary disease (COPD) are high, however data from Eastern European countries are scarce. We aimed to study healthcare...
The measurement of self-regulation in the Adolescent Brain Cognitive Development (ABCD) Study
To facilitate future research on self-regulation and related brain-behavior associations, we aimed to establish a psychometric model of self-regulation in the largest open neuroimaging dataset to date...
Biological knowledge combined with innovative engineering to reduce power plant impingement of horseshoe crabs
Electric generating plants (power plants) are often subject to regulatory requirements to comply with the impingement mortality reduction standards of Section 316(b) of the federal Clean Water Act. In...
Roscovitine enhances the bactericidal activity of the airway surface liquid of the cystic fibrosis bronchial epithelium but does not protect against Pseudomonas aeruginosa infection
Cystic fibrosis (CF) is the most common genetic diseases in the Caucasian population. CFTR defects, the most common being F508del, lead to abnormal mucus accumulation. Respiratory failure caused by th...
Effects of fluid shear stress duration on the mechanical properties of HeLa cells using atomic force microscopy
Cellular mechanical properties play a critical role in physiological and pathological processes, with fluid shear stress being a key determinant. Despite its importance, the impact of fluid shear stre...
Lake morphology and meteorological conditions impact stratification of saline lakes in the Atacama Desert
Saline lakes exist in various morphologies within salar environments, occurring as ephemeral to persistent bodies of water despite evaporative conditions. Salar environments are often characterized by...
Perceptions of COVID-19 risk among individuals with preexisting health conditions
Objectives To examine the association between the presence of preexisting health conditions (PEC) and the perceived risk of catching COVID-19 at the beginning of the pandemic and assess how risk perce...
A sequential three-way decision model based on linguistic Z-numbers
Linguistic Z-numbers (LZs), which uses both fuzzy constraint and reliability measure to describe information and has been widely used in various industries. However, as the amount of information neede...
Diagnostic accuracy of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in differentiating thyroid tumors: A systematic review and meta-analysis
Background Thyroid neoplasms include a range of lesions, most of which are benign, though some may progress to or present as malignant. Diagnostic tools like FNAB, ultrasound, and hormone analysis are...