PLoS ONE
Articles in this Issue
Resveratrol aggravated H2O2-induced the HK-2 cell damage by inhibiting AKT phosphorylation
Aims Reactive oxygen species (ROS) can induce renal damage when renal ischemia-reperfusion occurs as a result of factors such as renal transplant and shock. It is well established that oxidant damage...
Spatiotemporal patterns of water and vegetation in Poyang Lake from 2013 to 2021 using remote sensing data
Continuous monitoring and research on Poyang Lake is essential to understand its ecological dynamics and promote sustainable development. Spatial and temporal dynamic monitoring and analyses of vegeta...
Factors affecting quality of life in connective tissue disease-related interstitial lung disease
Background Connective tissue disease-related interstitial lung disease (CTD-ILD) results in an unrelenting symptom burden and may progress to death. The morbidity and mortality associated with CTD-ILD...
A computational Evo-Devo approach for elucidating the roles of PLETHORA transcription factors in regulating root development
PLETHORA (PLT) transcription factors play essential roles in regulating various developmental processes in plants, including embryogenesis, rhizotaxis, phyllotaxis, and most prominently, root developm...
Prioritizing the bottom line over people in a crisis: How leader behavior affects employee psychological distress under economic threat
Aim This study examines the impact of direct supervisors’ leadership on employee psychological distress during crises. Specifically, it explores the relationship between people-oriented and bottom-lin...
Characterization of a Drosophila model to study functions of guarana seeds
The seeds of the Amazonian fruit, guarana (Paullinia cupana), have been used as traditional medicine and, in recent years, as an ingredient in commercial energy beverages. However, mechanisms underlyi...
Prenatal developmental toxicity of Urtica simensis essential oil in rat embryos and rat fetuses
Pregnant women inhaled fresh U. simensis steam vapor to fumigate their bodies, and boiled it for tea. However, the safety of this practice during pregnancy has not yet been reported. This study aimed...
Detecting outbreaks using a spatial latent field
In this paper, we present a method for estimating the infection-rate of a disease as a spatial-temporal field. Our data comprises time-series case-counts of symptomatic patients in various areal units...
Small target detection algorithm based on the fusion attention mechanism and multi-layer convolution
In the realm of unmanned aerial vehicles, we proposed an enhanced small target detection algorithm, MGAC-YOLO, to address the challenges of missed detections and low accuracy associated with small tar...
Exploration of short-term predictions and long-term projections of Barents Sea cod biomass using statistical methods on data from dynamical models
This study aims to explore how well simple statistical modeling can generate short-term predictions and long-term projections of the total biomass of the Northeast Arctic stock of Atlantic cod (Gadus...
Reassessment of public awareness and prevention strategies for HIV and COVID-19 co-infections through epidemic modeling
A co–infection model between HIV and COVID-19 that takes into account COVID-19 vaccination and public awareness is discussed in this article. Rigorous analysis of the model is conducted to establish t...
Factors influencing the adoption of the BYOD policy in teaching hospitals: A cross-sectional study from Southeastern Iran
Introduction Clinicians are increasingly using their devices for work at hospitals, a practice known as Bring-your-own-device (BYOD), to enhance productivity and mobility. This study aimed to determin...
A multi-biomarker approach to risk stratification and detection of early cardiac disease in systemic sclerosis
Objective We sought to investigate the relationship between serum biomarkers of cardiac dysfunction, longitudinal strain on echocardiography, and all-cause mortality in patients with systemic sclerosi...
Correction: Identification of a disulfide bridge important for transport function of SNAT4 neutral amino acid transporter
Criterion-related validity of self-screening using the KOJI AWARENESS™ test for range of motion and strength in healthy participants
Objective This study aimed to establish the validity of the KOJI AWARENESS™ sub-components by determining whether there is a connection between the sub-component scores and joint range of motion, musc...
Unmasking the rising global burden of depression: A 32-year GBD analysis of gender disparities and regional hotspots in Sub-Saharan Africa
Aims Depression, a leading contributor to the global disease burden, exhibits alarming increases in incidence and prevalence, with pronounced disparities across regions and genders. This study provide...
Incidence of intraventricular haemorrhage, associated risk factors and short-term outcomes among preterm neonates in a tertiary referral hospital in Kenya
Background Intraventricular hemorrhage (IVH) stands as the predominant cause of brain injury with the incidence increasing with the decrease in birth weight and gestational age. In developed countries...
Smartphone dependence, addiction, and insomnia among medical students during the COVID-19 pandemic
Introduction During the COVID-19 pandemic, smartphone use among students increased, even before going to sleep, which resulted in an increased risk of dependence, addiction, and sleep problems such as...
A bearing fault diagnosis method based on hybrid artificial intelligence models
The working state of rolling bearing severely affects the performance of industrial equipment. Addressing the issue of that the difficulty of incipient weak signals feature extraction influences the r...
Post-caesarean section infection burden, antimicrobial resistance pattern, and associated factors at all Africa Leprosy Rehabilitation and Training Center Comprehensive Specialized Hospital, Addis Ababa, Ethiopia
Background Surgical site infections are a major concern in maternal healthcare, especially after cesarean sections (CSs), which are among the most common surgical procedures globally. The World Health...
Exploring the potential of synthetic and biological fungicides for managing the fungus-farming ambrosia beetle Xylosandrus compactus
Little is known about effective control strategies targeting the invasive ambrosia beetle Xylosandrus compactus. This fungus-farming beetle is highly dependent on its primary nutritional fungal mutual...
Determine the accuracy of CBCT reconstructed panoramic images in periodontal assessment
Objectives Periodontal probing and intraoral radiography are conventional methods for periodontal assessment. Evaluating periodontium using CBCT-reconstructed multiplanar or cross-sectional views is l...
Effects of repetitive head impacts from a single season on the cognitive functioning of youth male soccer players
Repetitive head impacts have long-lasting negative effects on the cognition of athletes. For example, repetitive head impacts accumulated by adult professional soccer players throughout their careers...
Transcriptome combined single-cell sequencing explores molecular mechanisms of ANGPTL4 in sepsis-induced acute lung injury
Objective Sepsis-induced acute lung injury (ALI) constitutes a critical clinical syndrome associated with high mortality rates, yet its molecular mechanisms remain inadequately elucidated. Recent evid...
Development and characterization of pramipexole dihydrochloride buccal films for Parkinson’s disease treatment
Parkinson’s disease is one of the most common neurodegenerative diseases worldwide. Swallowing difficulties present a significant challenge in the treatment of Parkinson’s disease patients. Our curren...