PLoS ONE
Articles in this Issue
Post-acute sequelae of COVID-19 in residents in long-term care homes: Examining symptoms and recovery over time
Background Post-COVID-19 condition (PCC) has been studied extensively since the inception of the COVID-19 pandemic. In the population of long-term care (LTC) home residents, however, information about...
Replacing non-biomedical concepts improves embedding of biomedical concepts
Embeddings are semantically meaningful representations of words in a vector space, commonly used to enhance downstream machine learning applications. Traditional biomedical embedding techniques often...
Evaluating miR-107 and adiponectin as biomarkers in obstructive sleep apnea: Associations with neurotransmitters and metabolic regulation
This study aimed to examine the levels of microRNA-107 (miR-107) and its correlation with neurotransmitters (glutamate, serotonin, melatonin) and adiponectin in patients with obstructive sleep apnea (...
Impaired gastric and urinary but preserved cardiac interoception in women with endometriosis
Endometriosis is a chronic inflammatory gynaecological condition frequently associated with chronic pelvic pain. Visceral hypersensitivity could be present, like in other chronic pain conditions, caus...
RETRACTED: Cardiovascular and mortality outcomes of DPP-4 inhibitors vs. sulfonylureas as metformin add-on therapy in patients with type 2 diabetes: A systematic review and meta-analysis
Background Type 2 diabetes significantly increase the risk of cardiovascular disease and mortality. This systematic review and meta-analysis compared cardiovascular and mortality o...
Use of allele-specific qPCR and PCR-RFLP analysis for rapid detection of the SARS-CoV-2 variants in Tunisia: A cheap flexible approach adapted for developing countries
Monitoring the emergence and propagation of SARS-COV2 variants, especially Omicron variants, remains a major concern in developing countries, including Tunisia. We here report lessons of simple approa...
Itaconate potentiates hepatic gluconeogenesis through NRF2 induction
The interplay between systemic metabolism and immune responses is increasingly recognized as a significant factor in the dysregulation of glucose homeostasis associated with diabetes and obesity. Immu...
Correction: Precise phenotyping method using image data for carcass marbling score in Hanwoo cattle
A study of systemic risk spillovers in Asian emerging markets and Chinese stock market
This study examines systemic risk spillover effects between China’s Shanghai Stock Exchange (SSE) and seven Asian emerging markets within the context of increasing global financial integration. Utiliz...
Inhibition of xpt Guanine Riboswitch by a synthetic nucleoside analog
Riboswitches are structured elements predominantly found in the 5’-untranslated region of many bacterial mRNA. These noncoding RNA regions play a vital role in bacterial metabolism and overall functio...
The roles and signalling pathways of lncMALAT1 in coronary artery disease: A protocol for systematic review of in vivo and in vitro studies
Background Coronary artery disease (CAD) is a major cardiovascular disease that affects global population health. Several studies have indicated the association between high expression level of a non-...
Discrimination of a single-item scale to measure intention to have a COVID-19 vaccine
Aim When developing public health measures in a pandemic, it is important to examine attitudes and beliefs relating to vaccination uptake. We report the discrimination of a single-item vaccination int...
Physical capacity is associated with attention but not with general executive function in middle aged adults
Associations between Physical Capacity (PC) and various aspects of executive function, including attention, have been identified in older and younger cohorts. Yet, the relationship among middle-aged i...
Histological study of donor/recipient feasibility in distal nerve transfer for the upper limb nerve injury
This study aimed to histologically investigate whether the compatibility of donor and recipient nerves in distal nerve transfer for radial and ulnar nerve palsy is suitable for restoring nerve functio...
The non-specific phospholipase C of common bean PvNPC4 modulates roots and nodule development
Plant phospholipase C (PLC) proteins are phospholipid-degrading enzymes classified into two subfamilies: phosphoinositide-specific PLCs (PI-PLCs) and non-specific PLCs (NPCs). PI-PLCs have been widely...
Prevalence of periodontitis in adolescents: A systematic review protocol
Periodontitis is considered an inflammatory disease that affects the tooth’s supporting structures, resulting in its progressive destruction, which can lead to several problems, such as loss of teeth,...
Non-communicable disease and mental health care during the COVID-19 pandemic in South Africa: Perspectives from selected healthcare professionals and patients
Aim South Africa has a high burden of non-communicable diseases (NCDs) and experienced a high COVID-19 caseload, while the healthcare system was already overstretched. The aim of this study was to exa...
Enhancing the communication of radiation exposure data for radiological workers in Korea using data visualization techniques
Effective communication of radiation exposure data is essential for improving safety management practices for radiological workers. However, traditional tabular formats used in reporting radiation exp...
Type 1 diabetes mellitus in children: Patient reported outcomes
The global prevalence of type 1 diabetes mellitus (T1DM) is increasing. Poor glycemic control in children and adolescents leads to both acute and chronic problems, reduced Health Related Quality of Li...
Puriton attenuates the asthma severity in ovalbumin-induced murine model via balancing Th1/Th2 and inhibiting inflammation
In 2019, 262 million asthma patients were estimated, with 455 thousand deaths caused by asthma. It is an incurable chronic inflammatory respiratory disease and is more severe in the elderly and in the...
TCN-QV: an attention-based deep learning method for long sequence time-series forecasting of gold prices
Accurate prediction of gold prices is crucial for investment decision-making and national risk management. The time series data of gold prices exhibits random fluctuations, non-linear characteristics,...
Characterization and identification of extrachromosomal circular DNA in cholangiocarcinoma
Extrachromosomal circular DNAs (eccDNAs) have gained attention as key players in cancer heterogeneity, potentially associated with elevated oncogene copy numbers in many cancers. While the presence of...
Identifying a predictive level of serum C-terminal telopeptide associated with a low risk of medication-related osteonecrosis of the jaw secondary to oral surgery: A systematic review and meta-analysis
Objective Our aim was to determine serum C-terminal telopeptide of type I collagen (sCTX) thresholds for predicting the minimal risk of medication-related osteonecrosis of the jaw (MRONJ) in patients...
New class of symmetric starlike functions subordinate to the generating function of Gregory coefficients
Function theory research has long struggled with the challenge of deriving sharp estimates for the coefficients of analytic and univalent functions. Researchers have advanced the field by developing a...
Elevated urine albumin-to-creatinine ratio as a risk factor for cognitive impairment in older adults: A cross-sectional analysis of NHANES data
Background Cognitive impairment is an escalating challenge in aging populations, with risk factors extending beyond traditional domains. The urine albumin-to-creatinine ratio (UACR), a marker of kidne...