Journal of Biological Chemistry

Abstract 2067 Actin-Regulatory Protein Profilin1 Plays an Important Role in Lipid Homeostasis

Andrew Orenberg, Michael Chirumbolo, Dave Gau et al. May 01, 2025 pp. 109420 10.1016/j.jbc.2025.109420

Abstract 2370 Characterizing DNA Binding Activity of the Transcription Factor TWIST1 and its Basic Domain Mutants

Antonio Cervoni, Alexandra Torres-Bracero, Jessicca Renta-Torres et al. May 01, 2025 pp. 109992 10.1016/j.jbc.2025.109992

Abstract 2914 Role of RNase L in the Spike Protein of SARS-CoV-2 (S-protein)-Induced Activation of Macrophages

Xiaotong Zhao, Isabel Paulesc, Aimin Zhou May 01, 2025 pp. 109382 10.1016/j.jbc.2025.109382

Transcription blocking properties and transcription-coupled repair of N2-alkylguanine adducts as a model for aldehyde-induced DNA damage

Leen Sarmini, Nataliya Kitsera, Mohammed Meabed et al. May 01, 2025 pp. 108459 10.1016/j.jbc.2025.108459

Abstract 1477 Mapping affinity and allostery of human IgG antibody Fc region interactions with endoglycosidases, and comparison of fucosylated/afucosylated Fc region interactions with activating and inhibitory Fc γ Receptors

Alasdair Keith, Ting Xu, Tatiana Chernova et al. May 01, 2025 pp. 109348 10.1016/j.jbc.2025.109348

Abstract 2275 Loss of PDGFRB/VEGFR2 perturbs cell-cell junction structure in retinal epithelial and retinoblastoma cells

Katherine Sinex, Vanessa Morales-Tirado, Matt Wilson et al. May 01, 2025 pp. 110120 10.1016/j.jbc.2025.110120

Abstract 2566 Intracellular pH regulates kinase signalling

Dominic Ng, Yuliia Didan, Milad Ghomlaghi et al. May 01, 2025 pp. 110125 10.1016/j.jbc.2025.110125

Abstract 2174 Allosteric Noncompetitive Inhibition of the Bacterial Enzyme N-Succinyl-L,L-2,6-Diaminopimelic Acid Desuccinylase (DapE)

Kenneth Olsen, Amanda Briggs, Emma Kelley et al. May 01, 2025 pp. 109059 10.1016/j.jbc.2025.109059

Abstract 2706 Engineered NLS-chimera downregulates expression of aggregation-prone endogenous FUS

Miyuki Hayashi, Jacquelyn DePierro, Lin Guo May 01, 2025 pp. 109720 10.1016/j.jbc.2025.109720

Abstract 1480 Eeyarestatin I (ESI) Stimulates JNK-dependent G2/M Arrest and Apoptosis and Downregulates Expression of Translocon-associated Proteins (TRAPs) in Human Colorectal Cancer Cells

Jing Peng, Cheng-I Wei, Seong-Ho Lee May 01, 2025 pp. 108657 10.1016/j.jbc.2025.108657

A major Toxoplasma serine protease inhibitor protects the parasite against gut-derived serine proteases and NETosis damage

Maryam Saffarian, Julia D. Romano, Michael E. Grigg et al. May 01, 2025 pp. 108457 10.1016/j.jbc.2025.108457

Abstract 1136 Engineering yeast Hsp104 through nucleotide-binding domain 2 to counter human proteotoxicity

Zarin Tabassum, Zoe Chen, Alondra Betancourt et al. May 01, 2025 pp. 109868 10.1016/j.jbc.2025.109868

Abstract 2405 Building functional chimeras for biosensing and synthetic biology using CRISPR

Jacinda Pujols, Kyutae Lee, Nick Kapolka et al. May 01, 2025 pp. 110160 10.1016/j.jbc.2025.110160

Abstract 2163 REDD2 protein abundance is controlled by redox-sensitive proteasomal degradation

Ashley VanCleave, Siddharth Sunilkumar, Christopher McCurry et al. May 01, 2025 pp. 109966 10.1016/j.jbc.2025.109966

Abstract 2207 Investigating the Molecular Mechanisms of the Heat Shock Response in Corals: Implications for Thermal Tolerance and Resilience to Climate Change

Saborni Chowdhury, Avery Kruger, Kate Fetkenhour et al. May 01, 2025 pp. 109972 10.1016/j.jbc.2025.109972

Abstract 2700 Stability of Metal Binding Domains of Wilson Disease Protein

David Huffman, Conor Handlogten, Thomas Gavan et al. May 01, 2025 pp. 108941 10.1016/j.jbc.2025.108941

Abstract 1242 Surveying helix 12 dynamics within constitutively active human estrogen receptors containing somatic Y537S and D538G mutations

Lasantha Sendanayake, Justin Holub May 01, 2025 pp. 108888 10.1016/j.jbc.2025.108888

Abstract 1418 Overexpression Methods for DesD to Investigate Binding Kinetics

Ashlee Bacconi, Katherine Hoffmann May 01, 2025 pp. 109119 10.1016/j.jbc.2025.109119

Abstract 1578 TMT-based quantitative proteomic analysis of lymphatic exosomes reveals pathways involved in sentinel lymph node remodeling in melanoma

Shankar Suman, Liyi Geng, Wendy Nevala et al. May 01, 2025 pp. 108664 10.1016/j.jbc.2025.108664

Abstract 1369 Modeling Isocitrate Dehydrogenase 2 Mutations in Acute Myeloid Leukemia: Exploring how the drug AG-221 Inhibits 2-hydroxyglutarate Production and Restores Blood Cell Differentiation

Jay Matta, Brianna Bourke, Bhumika Balani et al. May 01, 2025 pp. 108578 10.1016/j.jbc.2025.108578

Abstract 2436 Identification of a cysteine residue near an ERK1/2 substrate docking site and potential regulation of signaling involved in cell adhesion in A375 melanoma cells

Lena Grogan, Nathaniel McClean, Mohan Tulapurkar et al. May 01, 2025 pp. 108731 10.1016/j.jbc.2025.108731

Abstract 2785 Mapping the TMEM97-NPC1 interface

Ha Nguyen, Yu-Shiuan Cheng, Alison Ondrus May 01, 2025 pp. 108944 10.1016/j.jbc.2025.108944

Abstract 2701 NADK2 controls lipid processing and physiological homeostasis in vivo

Harrison Tom, Eunji Park, Trevor Tippetts et al. May 01, 2025 pp. 109548 10.1016/j.jbc.2025.109548

Abstract 1707 Characterization of the contribution of the Mediator complex subunit MED23 to H3K27me3 homeostasis

Shelby Sliger, Jiaxin Long, Joe Ogas May 01, 2025 pp. 109251 10.1016/j.jbc.2025.109251

Abstract 1588 Exploring Regulatory Mechanisms of Mannitol-Driven Biofilm Formation in Vibrio cholerae

Emmie Appl, Eleanor Mackey, Jane Liu May 01, 2025 pp. 109604 10.1016/j.jbc.2025.109604