Journal of Biological Chemistry

Alphaherpesvirus pUL21 homologs use non-canonical sequences to compete with cellular adaptors for protein phosphatase 1 binding

Holly Monkhouse, Daniela S. Carter-Lopez, Tomasz H. Benedyk et al. Jan 01, 2026 pp. 110936 10.1016/j.jbc.2025.110936

Cell wall arabinogalactan is responsible for Fungitell cross reactivity in nocardiosis

Christophe Mariller, Pascal Letowski, Wei-Ting Chang et al. Jan 01, 2026 pp. 110900 10.1016/j.jbc.2025.110900

Initiator and elongator tRNA recognition mechanism in Mycobacterium tuberculosis methionyl-tRNA synthetase

Shivani Thakur, Rukmankesh Mehra Jan 01, 2026 pp. 110939 10.1016/j.jbc.2025.110939

Integrin α5β1 mediates the inhibitory effects of vasoinhibin on angiogenesis and vascular permeability

Magdalena Zamora, Carmen Clapp, Gonzalo Martínez de la Escalera et al. Jan 01, 2026 pp. 110978 10.1016/j.jbc.2025.110978

Profiling the TRPV4 ankyrin repeat domain interactome and its disruption by neuromuscular disease-causing mutations

Alexis K. Loder, Gage P. Kosmanopoulos, William H. Aisenberg et al. Jan 01, 2026 pp. 110991 10.1016/j.jbc.2025.110991

Coiled-coil register transitions and coupling with the effector’s inhibitory site enables high fold changes in blue light–regulated diguanylate cyclases

Uršula Vide, Gabriela Shickle, Julia Schwekendiek et al. Jan 01, 2026 pp. 111020 10.1016/j.jbc.2025.111020

Regulation of Kv2.1 biogenesis and gating by candidate disease-linked Kv6.1 variants

Damayantee Das, Shawn M. Lamothe, Nicholas C. Duta et al. Jan 01, 2026 pp. 110943 10.1016/j.jbc.2025.110943

Mutations in Hsp40 co-chaperone change the canonical interdomain interactions stimulating LGMDD1 myopathy

Ankan K. Bhadra, Geetika Aggarwal, Anshuman Jaysingh et al. Jan 01, 2026 pp. 110945 10.1016/j.jbc.2025.110945

Cryo-EM structure of the ATP11C Q79E mutant reveals the structural basis for altered Phospholipid recognition

Yuheng Qian, Chai C. Gopalasingam, Christoph Gerle et al. Jan 01, 2026 pp. 110935 10.1016/j.jbc.2025.110935

Phosphorylation at S1288 of leukemia associated RhoGEF (LARG/ARHGEF12) induces plasma membrane localization and promotes binding and activation of RhoA

Won Seok Yang, Neda Z. Ghanem, Steven D. Scahill et al. Jan 01, 2026 pp. 110996 10.1016/j.jbc.2025.110996

Cholesterol promotes the formation of dimers and oligomers of the receptor tyrosine kinase ROR1

Alyssa Ward, Luis J. Baeza-Ballesteros, Ryan Schuck et al. Jan 01, 2026 pp. 111000 10.1016/j.jbc.2025.111000

HMGN1 and HMGN2 are recruited to acetylated and histone variant H2A.Z-containing nucleosomes to regulate chromatin state and transcription

Riya Gohil, Zhihan Gao, Rebecca A. Lewis et al. Jan 01, 2026 pp. 110997 10.1016/j.jbc.2025.110997

E3 ubiquitin ligase TRIM47 promotes intrahepatic cholangiocarcinoma progression by ubiquitinating fumarate hydratase and modulating macrophage polarization

Yanyang Fu, Jixing Wu, Jian Shi et al. Jan 01, 2026 pp. 111035 10.1016/j.jbc.2025.111035

Spontaneous dimerization of the hepatitis C virus 3′X RNA

Parker D. Sperstad, Erik D. Holmstrom Jan 01, 2026 pp. 110963 10.1016/j.jbc.2025.110963

Dynamic control of bacterial antiphage defense through the CdnG–Cap5 cyclic oligonucleotide–based antiphage pathway in Vibrio cholerae

Feng Ye, Jiaao Gong, Yao Ge et al. Jan 01, 2026 pp. 111021 10.1016/j.jbc.2025.111021

Kallikrein 14 activates the chemoattractant protein chemerin in human skin

Piotr Brzoza, Mariia Tyshchenko, Tomasz Kantyka et al. Jan 01, 2026 pp. 111002 10.1016/j.jbc.2025.111002

Metabolic and epigenetic abnormalities cause hepatic fibrogenesis in metabolic dysfunction–associated steatohepatitis model mice

Atsushi Miura, Shiori Ikeda, Yuki Kono et al. Jan 01, 2026 pp. 110959 10.1016/j.jbc.2025.110959

Development of a recombinant membrane protein ELISA for analyzing antibody responses against SARS-CoV-2 envelope proteins

Sylvie Chabot, Tahir Malik, Lila Saye et al. Jan 01, 2026 pp. 110974 10.1016/j.jbc.2025.110974

The mitotic functions of a fission yeast CK1 enzyme are regulated by Cdk1-dependent and auto-phosphorylation

Kazutoshi Akizuki, Sierra N. Cullati, Alyssa E. Johnson et al. Jan 01, 2026 pp. 111007 10.1016/j.jbc.2025.111007

Regulatory role for tumor suppressor REST on estrogen receptor (ESR1) expression and leiomyoma pathophysiology

Skylar G. Bird, Sumedha Gunewardena, Ashley Cloud et al. Jan 01, 2026 pp. 111017 10.1016/j.jbc.2025.111017

Enhancing O-linking oligosaccharyltransferase functionality through directed evolution

Rachel L. Edwards, Kathleen N. McAllister, Jenna C. McGuffey et al. Jan 01, 2026 pp. 110885 10.1016/j.jbc.2025.110885

A humanized transferrin receptor 1-transferrin model supports functional iron homeostasis and therapeutic delivery across the blood–brain barrier

Metin Yesiltepe, Sanjay Metkar, Tao Yin et al. Jan 01, 2026 pp. 110995 10.1016/j.jbc.2025.110995

Minimal actin cortices: The αD-helix of ezrin's C-ERMAD governs F-actin binding

Elena Lisa Maria Ackermann, Johanna Rathke, Tim Heißenberg et al. Jan 01, 2026 pp. 111031 10.1016/j.jbc.2025.111031

Discovery of small molecule modulators of the thin filament that alter the contractile profile in a hypertrophic cardiomyopathy engineered tissue model

Ruth F. Sommese, Samuel M. Levi, Janice Brown et al. Jan 01, 2026 pp. 110938 10.1016/j.jbc.2025.110938

Dynamic acetylation of a conserved lysine impacts glycerol kinase activity and abundance in the haloarchaeon Haloferax volcanii

Karol M. Sanchez, Manasa Addagarla, Heather N. Judd et al. Jan 01, 2026 pp. 110960 10.1016/j.jbc.2025.110960