Journal of Biological Chemistry

Abstract 3504 SARS-CoV-2 ORF3a blocks lysosomal cholesterol egress by disrupting VPS39-regulated protein trafficking and BMP metabolism

Jing Pu, Baley Goodson, Valeria Montenegro Vazquez et al. May 01, 2026 pp. 112226 10.1016/j.jbc.2026.112226

Abstract 5620 Electrostatic interactions with anionic lipids drive membrane association of PLCβ enzymes

Maria Falzone, Makayla Crawford, Marie Bennett et al. May 01, 2026 pp. 112273 10.1016/j.jbc.2026.112273

Abstract 3892 Broadening the scope of a colorimetric assay for adenylate formation

Madeline Tabora, Joseph Chihade May 01, 2026 pp. 112041 10.1016/j.jbc.2026.112041

Abstract 3866 Evaluation of the synergistic properties of standard of care chemotherapeutics with Protein Kinase C agonists in Triple-Negative Breast Cancer

Marelly Perez, Charles Fermaintt, April Risinger May 01, 2026 pp. 111925 10.1016/j.jbc.2026.111925

Abstract 2269 Histone decrotonylation plays a unique role in regulating HIV latency

Guochun Jiang, Xiaoyi Li, Yuyang Tang et al. May 01, 2026 pp. 111775 10.1016/j.jbc.2026.111775

Abstract 3963 Characterization of TonB4 and TonB6 Proteins in Bacteroides thetaiotaomicron through generation of multiple gene deletion strains

Chloe Lucas, Kalina Rashkov, Nisrine Jabara et al. May 01, 2026 pp. 112335 10.1016/j.jbc.2026.112335

Abstract 5634 Inflammatory Caspases Cleave hnRNP K to Promote Bacterial Immunity

Christopher Bourne, Simon Boudreault, Madhura Kulkarni et al. May 01, 2026 pp. 112197 10.1016/j.jbc.2026.112197

Abstract 4197 Engineering a Full-Length A2A Receptor via Sortase A-Mediated Tail Ligation to Uncover C-Terminal Regulatory Mechanisms

Trang Ma, Xudong Wang, Libin Ye May 01, 2026 pp. 112957 10.1016/j.jbc.2026.112957

Abstract 2338 Heat-induced activation of PI4KIIIα drives phosphatidylinositol 4-phosphate accumulation and HSPA1A membrane localization

Azalea Blythe Cuaresma, Clarisse Kate Martin, Jensen Low et al. May 01, 2026 pp. 112221 10.1016/j.jbc.2026.112221

Abstract 5732 Empowering Structural Determination through X-ray Crystallography at the National Crystallization Center

Gabrielle Budziszewski, Tiffany Wright, M. Elizabeth Snell et al. May 01, 2026 pp. 112887 10.1016/j.jbc.2026.112887

Abstract 2312 Exploring PKA's Conformational Selection Mechanism using Monte Carlo Simulations

Sonya Savelyev, Mira Malmosi, Lydia Good et al. May 01, 2026 pp. 111841 10.1016/j.jbc.2026.111841

Abstract 4331 Large-Scale Constraint-Driven Modeling of PROTAC Ternary Complexes Using the PRosettaC Pipeline Across PROTAC-DB 3.0

Joseph Schulz, CAM Buscaron, Tillman Pearce et al. May 01, 2026 pp. 111870 10.1016/j.jbc.2026.111870

Abstract 4105 Characterizing the Specificity of the ASCC2 CUE Domain for K63-linked Polyubiquitin at Loci of RNA Transcription Alkylation

Andrew Starvaggi, Patrick Lombardi, Madeline Mullen et al. May 01, 2026 pp. 112813 10.1016/j.jbc.2026.112813

Abstract 2129 CDC123 functional impairments noncanonically induce the Integrated Stress Response and are linked to a novel neurodevelopmental disorder

Anthony Erb, Ambar Rodriguez-Martinez, Alexandra Misciagna et al. May 01, 2026 pp. 111701 10.1016/j.jbc.2026.111701

Abstract 3920 Tissue-specific responses to low PC allow an ARF GTPase "swap” as membrane properties change

Amy Walker, Arjamand Mushtaq May 01, 2026 pp. 112244 10.1016/j.jbc.2026.112244

Abstract 3699 Thermodynamic characterization of binding between human lactadherin and cold-inducible RNA-binding protein

P. Clint Spiegel, Ava Horton, Kessa Russell et al. May 01, 2026 pp. 112744 10.1016/j.jbc.2026.112744

Abstract 4495 Immune and Inflammatory Pathways in Schwannomatosis-Associated Pain: Insights from Gene Expression Profiling

Chrissa Baldy May 01, 2026 pp. 112521 10.1016/j.jbc.2026.112521

Abstract 3717 RiboMarker®-Enhanced RNA Sequencing Reveals Small RNA Profiles and Transcriptomic Dynamics in Coccidioides posadasii

Tahirah Williams, Jonathan Howard, Aidan Manning et al. May 01, 2026 pp. 112627 10.1016/j.jbc.2026.112627

Abstract 6837 Regulation of the ABC Transporter MsbA by Lipids, Nucleotides, and Divalent Metals

Arthur Laganowsky May 01, 2026 pp. 112289 10.1016/j.jbc.2026.112289

Abstract 4182 De Novo Design of a Protein Binder for Citrus Red No.2

Luxel Moliko Djouba, Amanda Liyanaarachchi, Sagar Khare May 01, 2026 pp. 112826 10.1016/j.jbc.2026.112826

Abstract 6825 Fishing for targets: chemical proteomics strategies for anti-parasitic drug target deconvolution

Susan Wyllie May 01, 2026 pp. 111966 10.1016/j.jbc.2026.111966

Abstract 5630 Beyond cystine transport: cystinosin regulates ZNRF1-dependent glycosylation in cystinosis

Sumanth Mosale, Richa Sardana May 01, 2026 pp. 111751 10.1016/j.jbc.2026.111751

Abstract 4000 Harnessing Type III-A CRISPR-Cas for Sickle Cell Anemia Mutation Detection

Luqman Ajisafe, Calvin Perdigao, Jack Dunkle May 01, 2026 pp. 112575 10.1016/j.jbc.2026.112575

Abstract 5557 Charge Neutralization at Lys609 Modulates Catalysis and Interdomain Dynamics of Endothelial Nitric Oxide Synthase

Mohammad Masood, Rupesh Chaturvedi, Mohammad Mahfuzul Haque May 01, 2026 pp. 112080 10.1016/j.jbc.2026.112080

Abstract 3974 Pathogenic or not Pathogenic: Sequence Variant Classification Rules for Ornithine Transcarbamylase, N-Acetylglutamate Synthase and Carbamylphosphate Synthetase 1

Ljubica Caldovic, Kennedy Blancher, Yem Nguimbous et al. May 01, 2026 pp. 113011 10.1016/j.jbc.2026.113011