Journal of Biological Chemistry

The ASC-c isoform as a modulator of inflammasome activation: Insights into molecular mechanisms and therapeutic applications

Meenakshi Sharma, Anthony Waterston, Christopher J. Randolph et al. May 01, 2026 pp. 111353 10.1016/j.jbc.2026.111353

Abstract 2243 Evaluation of Membrane Interactions and Permeabilization of Daptomycin

Samuel Pennock, Maggie Cortez, Maxine Morano et al. May 01, 2026 pp. 112216 10.1016/j.jbc.2026.112216

Abstract 4054 Proteomic and Virological Characterization of Tupanvirus Deep Ocean, A Hairy Monster from the Deep

Mariana Michalakis, Rachel Vandersea, Eugene Wu May 01, 2026 pp. 112337 10.1016/j.jbc.2026.112337

Abstract 5788 Stem Cell Aging: local and systemic effects

Heinrich Jasper May 01, 2026 pp. 112972 10.1016/j.jbc.2026.112972

Abstract 3810 Uncovering the role of accessory proteins in poison exon inclusion by splicing modulator compounds

Frédéric Vaillancourt May 01, 2026 pp. 111791 10.1016/j.jbc.2026.111791

Abstract 5723 Mapping OGTs Network: Mechanistic Clues to Cardiac Cytoprotection

Fiddia Zahra, Bhargavi Narayanan, Robert O'Meally et al. May 01, 2026 pp. 112638 10.1016/j.jbc.2026.112638

Age-dependent induction of ER stress in retinal pigment epithelium impairs phagocytosis via ADAM17-dependent MERTK shedding

Hiroto Yasuda, Shinsuke Nakamura, Aimi Shirakawa et al. May 01, 2026 pp. 111397 10.1016/j.jbc.2026.111397

Abstract 3674 Refining Potent STAT3 Inhibitor Structure Through Molecular Docking

Arthur Sikora, Marqus Colon, Dev Patel et al. May 01, 2026 pp. 111852 10.1016/j.jbc.2026.111852

Abstract 3465 Modeling the Disruption of Binding of Three IgE Antibodies with Six Mutated Interaction Sites on the Arah2 Allergen

Aashi Chhabra, Hansi Parmar, Amaan Khan et al. May 01, 2026 pp. 112171 10.1016/j.jbc.2026.112171

Abstract 5722 Alterations in Host Glycan Utilization Associated with Bladder Disorders

Nuzhat Hoque, Nathan Boyer, Lisa Karstens et al. May 01, 2026 pp. 111879 10.1016/j.jbc.2026.111879

Abstract 5718 Retatrutide: The Future of Weight Loss Medications

Daniel Shannon, Scott Kaplan, Giovanni Mikesell et al. May 01, 2026 pp. 111958 10.1016/j.jbc.2026.111958

Abstract 3599 Differential Role of Bradykinin Receptors B1 and B2 on Bone Cell Differentiation and Function

Subramanya Pandruvada, Mitchell Piacsek, Charles Holjencin et al. May 01, 2026 pp. 111719 10.1016/j.jbc.2026.111719

Prolyl-3-hydroxylase 1 is a central regulator of collagen post-translational modifications and the collagen biosynthetic network

Claudia A. Staab-Weijnitz, Juliane Merl-Pham, Elisabeth Hennen et al. May 01, 2026 pp. 111422 10.1016/j.jbc.2026.111422

Abstract 3800 Delta-4-Desaturase (Δ4Des) from DHA-Rich Microalgal species: For Metabolic Engineering and Nutraceutical Applications

Sugasini Dhavamani, Kathiresan Shanmugam May 01, 2026 pp. 112652 10.1016/j.jbc.2026.112652

Abstract 4416 High-Resolution Detection of Post-Translational Modifications Using Single-Molecule Protein Sequencing

Meredith Carpenter, Natchanon Sittipongpittaya, Kendrick Nguyen et al. May 01, 2026 pp. 112852 10.1016/j.jbc.2026.112852

Abstract 3708 ZMIZ1 MODULATES COHESIN FUNCTION AND CGAS-STING PATHWAY ACTIVATION TO DRIVE OSTEOSARCOMA PROGRESSION

Hualong Yan, Payel Mondal, Gamze Ayaz et al. May 01, 2026 pp. 111617 10.1016/j.jbc.2026.111617

Abstract 4358 Formulation of surface modified RGD- solid lipid nanoparticles for delivering siRNA to triple negative breast cancer cell lines

Kruyanshi Master, Lujain Al-Khalaileh, Mir Hossain et al. May 01, 2026 pp. 111658 10.1016/j.jbc.2026.111658

Abstract 4354 Novel SINE Inhibitor Induces Apoptosis in Jurkat Leukemia Cells

Roslyn Crowder, Isabella Fortin, Victoria Savoie et al. May 01, 2026 pp. 111657 10.1016/j.jbc.2026.111657

Abstract 4469 A Biocatalysis-to-Biology Strategy to Target the Dynamic Coactivator Med25

Ana Martinez, Caroline Spancake, Katherine Torma et al. May 01, 2026 pp. 111816 10.1016/j.jbc.2026.111816

Abstract 3613 Investigation of Atg10's effect on autophagic body size and number

Pablo Demerath, Juan Salcedo, Olivia Clarino et al. May 01, 2026 pp. 112735 10.1016/j.jbc.2026.112735

Abstract 4180 New and Unexpected Findings in the Metabolism of Inositol Pyrophosphate in Candida albicans

Emmanuel Olotu, Ronda Rolfes May 01, 2026 pp. 112435 10.1016/j.jbc.2026.112435

Abstract 4155 Investigating the Functional Differences of Human eEF1As in tRNA Aminoacylation and Their Role in Peripheral Neuropathies

Gabriela Soriano, Juan Maldonado, Edwin Cruz et al. May 01, 2026 pp. 112058 10.1016/j.jbc.2026.112058

Abstract 3852 Structural Basis for Nucleotide Binding and Conformational Regulation of Anaplasma phagocytophilum Guanylate Kinase

Aniyah Barnett, Emma Sere, Evan Sturgill et al. May 01, 2026 pp. 112772 10.1016/j.jbc.2026.112772

Abstract 2135 Interaction between KATP Channels and EPAC2 during Chronic Opioid Exposure

Amy De Lury, Sunna Mujteba, Amanda Klein May 01, 2026 pp. 111888 10.1016/j.jbc.2026.111888

Abstract 4055 The Drosophila PDGF/VEGF signaling pathway regulates host immunometabolism in response to parasitoid infection

Abraham Kpirikai, Ashley Waring-Sparks, Luke Marney et al. May 01, 2026 pp. 112422 10.1016/j.jbc.2026.112422