PLoS ONE
Articles in this Issue
Epidemiology of Traumatic brain injury in Ethiopia: A systematic review and meta-analysis of prevalence, mechanisms, and outcomes
Introduction Traumatic brain injury (TBI) is a major cause morbidity and mortality globally. In Ethiopia, the prevalence of TBI is high, driven by factors such as road traffic incidents (RTIs), assaul...
What we know and don’t know about the antenatal care service utilization in Ethiopia: A scoping review of the literature
Introduction In Ethiopia, there has been considerable recent investment and prioritization in the maternal health program. However, coverage rates have been low and stagnant for a long time, indicatin...
The influence of the Big Five inventory on quality of life in people with Parkinson’s disease aged 50 and above: A Longitudinal Analysis from the Survey of Health, Aging and Retirement in Europe (SHARE)
Background Parkinson’s disease (PD) significantly reduces quality of life (QoL), particularly due to its complex interplay of motor and nonmotor symptoms. While personality traits influence QoL in chr...
Efficacy and safety of botulinum toxin-A injection in the treatment of premature ejaculation: A systematic review and meta-analysis
Introduction Premature ejaculation (PE) is a common male sexual dysfunction, impacting sexual satisfaction and quality of life. Botulinum toxin-A (BoNT-A), known for its muscle-relaxing properties, ha...
Perspectives of a mobile intervention for kidney transplant seekers: Post-intervention qualitative results from the KidneyTIME study
Objective Mobile health education could expand accessibility, but limited research has explored attitudes about such products among kidney transplant (KT) seekers. This study aimed to assess KT-seeker...
Association of predicted lean body mass and fat mass with prognosis in patients with heart failure preserved ejection fraction
Background Previous studies have shown that body composition influences the prognosis of heart failure patients; however, the prognostic value of lean body mass and fat mass in patients with heart fai...
Behavioral and emotional difficulties in maltreated children: Associations with epigenetic clock changes and visual attention to social cues
Research indicates that childhood maltreatment leads to adverse outcomes later in life and accelerated aging. However, few studies have investigated how age acceleration manifests during childhood. Th...
ArsenicNet: An efficient way of arsenic skin disease detection using enriched fusion Xception model
Arsenic contamination of drinking water is a significant health risk. Countries such as Bangladesh’s rural areas and regions are in the red alert zone because groundwater is the only primary source of...
Impact of living kidney donation on blood pressure and arterial stiffness: Systematic review and meta-analysis
Background We aimed to conduct a systematic review and meta-analysis (PROSPERO CRD42023480478) regarding the impact of kidney donation on arterial stiffness indices such as pulse wave velocity (PWV) a...
Exploring the feasibility, effectiveness, and acceptability of telehealth for delivering a pain management group program: A retrospective study
Objective The COVID-19 pandemic caused significant changes in healthcare, particularly in pain management. To maintain care, the Multidisciplinary Activity Improvement Program (MAiP), at the Departmen...
Computational investigation and experimental validation of the molecular mechanism of Solanecio mannii aqueous roots extract against cervical cancer
Cervical cancer remains one of the leading causes of cancer-related mortality among women worldwide, particularly in low- and middle-income countries, highlighting the need for improved strategies in...
Prediction of drug-target interactions based on substructure subsequences and cross-public attention mechanism
Drug-target interactions (DTIs) play a critical role in drug discovery and repurposing. Deep learning-based methods for predicting drug-target interactions are more efficient than wet-lab experiments....
Enhancing the dataset of CycleGAN-M and YOLOv8s-KEF for identifying apple leaf diseases
Accurate diagnosis of apple diseases is vital for tree health, yield improvement, and minimizing economic losses. This study introduces a deep learning-based model to tackle issues like limited datase...
Measuring alignment of structural proteins in engineered tissue constructs using polarized Raman spectroscopy
Measures of structural protein alignment within biological and engineered tissues are needed for improved understanding of their mechanical behavior and functionality. We advance our method of measuri...
3-Deoxysappanchalcone attenuates LPS-induced neuroinflammation in microglia cell culture and ameliorates cognitive impairment in traumatic brain injury
Background As one of the major public health security problems, traumatic brain injury (TBI) is characterized by cerebral dysfunction. The following neuroinflammation is considered as the main seconda...
Predictive modeling of hemoglobin refractive index using Gaussian process regression with interpretability through partial dependence plots
Accurately predicting the refractive index of hemoglobin across various wavelengths and concentrations is critical for advancing optical diagnostic techniques in biological and clinical applications....
Lessons learned from the COVID-19 pandemic in Latin America: A Data Science standpoint
In the 21st century, the world has faced the devastating impacts of three acute respiratory diseases: Middle East respiratory Syndrome (MERS), Severe Acute respiratory Syndrome (SARS), and COVID-19, w...
Risk factors for, metrics of, and consequences of access to veterinary care for companion animals: A scoping review
Background Barriers to accessing veterinary care can be challenging for companion-animal caregivers and may lead to preventable health conditions or even death of pets. Objectives We conducted a sco...
A novel experimental design approach to generating orbital angular momentum waves using wearable textile antenna for sub-6 GHz 5G
This paper presents a novel wearable textile array antenna designed to generate Orbital Angular Momentum (OAM) waves with mode + 1 at 3.5 GHz (3.4 to 3.6 GHz) of the sub-6 GHz 5G New Radio (NR) band....
Functional trait identity regulates productivity better than tree diversity and structural complexity in subtropical mixed-species forests
Subtropical forests play an important role in global carbon cycle and in mitigating climate change. Understanding the relationship between multiple diversity and ecosystem function is crucial for prot...
Exploring the impact of nature connectedness on well-being and mental distress among urban youth: Evidence from 25 most populated cities in India
In contemporary urban settings, enhancing the well-being of youth is a challenge. The proliferation of screen time, particularly post-pandemic, has contributed to an alarming disconnection with nature...
Integrated pan-cancer analysis revealed therapeutic targets in the ABC transporter protein family
Next-generation sequencing technology enables uniform and impartial assessment of cancer diagnoses and prognosis. However, such studies are mostly type-specific, and capturing shared genomic abnormali...
Lessons from a systematic tracing process aimed to reduce initial loss to follow-up (ILTFU) among people diagnosed with tuberculosis (TB) in Cape Town, South Africa
Background South Africa is a high tuberculosis (TB) burdened country. People who are newly diagnosed with TB must link to a TB treatment facility and be registered in the electronic TB notification sy...
Integrated nutritional care in long-term care: From theory to evidence-based practice
Against the background of ageing societies and worldwide growing populations with complex care needs, the reorganization of health and social care provision from fragmented towards integrated healthca...
Effects of whole-body vibration training on muscle performance in healthy women: A systematic review and meta-analysis of randomized controlled trials
Objective This study aimed to perform a comprehensive meta-analysis of randomized controlled trials examining the effectiveness of whole-body vibration training (WBVT) on muscle performance in healthy...