PLoS ONE
Articles in this Issue
Neurological outcomes and predictive factors in traumatic spinal cord injury patients in the intensive care unit
Background This study aims to analyze the demographic characteristics, clinical features, and neurological outcomes of patients with traumatic spinal cord injury (TSCI) admitted to the Intensive Care...
Informer-based DDoS attack detection method for the power Internet of Things
With the rapid development of smart grids, power grid systems are becoming increasingly complex, posing significant challenges to their security. Traditional network intrusion detection systems often...
Effects of dietary of Bacillus coagulans, whey powder, and their interaction on the performance of Lohmann LSL-lite laying hens in the late production phase
Due to the need to produce high-quality and healthy eggs, the current experiment was conducted to investigate the impact of dietary supplementation of whey powder (WP), Bacillus coagulans (B. coagulan...
Findings from transcriptomics and immunohistochemistry indicate an autoimmune disease targeting brainstem inhibitory interneurons in bovine spastic paresis
Bovine spastic paresis (BSP) is a progressive neuromuscular disease of unknown origin that causes persistent stiffness of the hind limbs. The symptoms are similar to those of human motor neuron diseas...
The removal of black ink via Emericella quadrilineata as a green alternative technique to recycling ink waste papers
In order to fight deforestation, biological methods of recycling printed waste papers must be used. In addition to identifying and isolating A. quadrilineatus, the current study attempts to ascertain...
The impact of baseline laboratory tests on the management of new-onset hypertension in primary care: A pilot study
Background Hypertension is a key contributor to the global cardiovascular disease burden. In 2021, the World Health Organization (WHO) hypertension management guideline suggested baseline laboratory t...
Maternal health care services utilization and associated factors among pregnant women in Kersa district, Jimma zone, Southwest Ethiopia
Background Ethiopia has a high rate of maternal mortality, documented at 412 deaths per 100,000 live births in 2016. One of the most important interventions to reduce maternal death from pregnancy-rel...
Sleep phenotyping in a rat model of susceptibility to substance use disorders
Alcohol use disorders (AUD) are bidirectionally associated with significant sleep disturbances, yet the underlying neural mechanisms remain poorly understood. The Marchigian Sardinian alcohol Preferri...
Feasibility of shear wave elastography for assessing steatosis in early-stage non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic fat accumulation with varying degrees of severity. This study aimed to evaluate the feasibility of shear wave elastography (SWE) f...
Correction: Attitudes, practices, and zoonoses awareness of community members involved in the bushmeat trade near Murchison Falls National Park, northern Uganda
The role of obesity in physiological stress, balance, and proprioception during repetitive manual material handling tasks
Manual laborers often experience fatigue-related incidents, which increase their risk of balance disturbances and falls. Previous research indicates that obese individuals may reach critical fatigue l...
The early-life fecal microbiota is associated with litter of origin but not with susceptibility to ETEC F4ab-mediated post-weaning diarrhea in CHCF1 genotyped pigs
Introduction Universal biomarkers in the fecal microbiota that predict susceptibility to post-weaning diarrhea (PWD) would be valuable for future intervention strategies. Genetic susceptibility to ent...
Ultra-orphan diseases: A cross-sectional quantitative analysis of the natural history of isolated sulfite oxidase deficiency
Objective Isolated sulfite oxidase deficiency (ISOD; OMIM #272300) is a devastating rare neurometabolic disorder due to biallelic pathogenic variants in the SUOX gene, that typically results in neonat...
Bidirectional genetic links between chronic obstructive pulmonary disease and frailty: Genome-wide association study insights
Background Recent research underscores a potential correlation between chronic obstructive pulmonary disease (COPD) and frailty, suggesting a shared genetic foundation. However, specific genetic facto...
Self-reported life experiences of members of the LGBTQ+ community in Accra, Ghana
Background Lesbian, Gay, Bisexual, Transgender, Queer/Questioning (LGBTQ+) community members encompass individuals whose sexual orientations and gender identities do not align with the heterosexual no...
Making the best of a bad sample: Comparison of DNA extraction and quantification methods using sub-optimally stored Ixodes ricinus ticks
The primary aim of this study was to evaluate the performance of four DNA extraction methods on a collection of 200 sub-optimally stored Ixodes ricinus ticks from Southeastern Norway (177 nymphs, 11 m...
The effect of traditional Thai massage vs routine physical therapy on gait pattern in spastic cerebral palsy: A cross-over randomized controlled trial
Background Various types of massage, including the traditional Thai, have not yet provided conclusive evidence to reduce the spasticity and improve walking ability for cerebral palsy (CP). Objective...
Food label literacy among Malaysian school adolescents: A prevalence study
Making informed food choices is crucial for all ages, especially adolescents who are involved in selecting and buying food. Understanding nutrition labels helps guide choices and ensures nutritional n...
Gender perspectives on zoonotic disease epidemiology; A strength weakness opportunities threats analysis in Bundibugyo district, Uganda
Background Gender mainstreaming in zoonotic disease prevention and control is paramount to produce sustainable solutions as well as keeping communities at the human-animal-environment interface safe a...
The analysis of waste heat recovery in steel enterprises’ data centers based on the Co-ah cycle
To improve the energy economic efficiency of Data Centers (DCs) in steel enterprises, a centralized heating scheme for waste heat recovery based on the Co-ah cycle is proposed. This scheme establishes...
Heat shock transcription factor 2 reduces mitochondrial pathway apoptosis in intestinal epithelial cells by inhibiting the increase in mitochondrial membrane permeability in ulcerative colitis
The destruction of intestinal mucosal mechanical barrier homeostasis caused by excessive apoptosis of intestinal epithelial cells (IECs) is an important reason for the occurrence and development of ul...
Numerical study on the supersonic gas-solid two-phase injection mechanism of needle-free syringe
Supersonic gas-solid injection technology finds extensive use in drug particle delivery systems. However, the combined impact of particle diameter and mass flow rate on the delivery efficiency remain...
Deep-embedded clustering by relevant scales and genome-wide association study in autism
Autism spectrum disorder (ASD) presents with heterogeneous phenotypic and genetic characteristics. Despite investigation into the molecular mechanisms underlying ASD, its etiology remains elusive. In...
Identification and validation of intergeneric hybrids between Saccharum officinarum and Erianthus rockii using molecular and cytogenetic tools
Sugarcane (Saccharum spp.), a vital crop for sugar and bioenergy production, faces challenges in breeding due to its narrow genetic base and susceptibility to environmental stresses. To enhance geneti...
The motivational foundations of childbearing: Investigating relationships between childbearing attitudes, value preferences, and parental bonding
This study aims to reveal the motivational foundations of childbearing. To achieve this goal, we investigated how general motivational goals expressed in personal value preferences and relationships w...