PLoS ONE
Articles in this Issue
Identifying key factors in building fires: A novel approach fusing K-shell entropy gravity
Building fire key factors are the fundamental control variables that govern both the initiation of fires and dynamics of propagation. The accurate identification of key factors in building fires is cr...
Seasonal variation in species composition, deltamethrin susceptibility, and kdr mutations in anopheles mosquitoes in Northwest Ethiopia
Background Anopheles mosquitoes are the main vectors of malaria. Effective vector control depends on understanding their species composition, behavior, distr...
Leveraging nonlinear relationships and interactions to improve 30-day pneumonia readmission machine learning models
Background Research is needed to develop more accurate readmission prediction models that identify patients at the highest risk of readmission after their initial pneumonia hospita...
Ceftibuten-polymyxin B combination alters resistance and cell wall gene expression in multidrug-resistant Klebsiella pneumoniae
Background Multidrug-resistant Klebsiella pneumoniae , including carbapenem- and polymyxin-resistant strains, pos...
Breaking barriers: Validation of a Spanish oral health knowledge tool to enhance patient-provider communication
Objectives This study aimed to develop and validate the Knowledge Related to Oral Health Literacy Spanish (KROHL- S) instrument to assess oral health knowledge among Spanish-speaki...
Comprehensive chemical, morphological, thermal, and biological characterization of Agave tequilana extract and chitosan-based dissolving microneedle arrays
Dissolving microneedles have gained attention as minimally invasive platforms for transdermal research applications. In this study, chitosan‑based dissolving microneedle arrays incorporating a hydroal...
Prevalence and incidence of balance disorders in community-dwelling older adults: Protocol for the EPIBAS epidemiological balance study
Background Poor balance leads to falls, which can cause a loss of personal autonomy and reduced quality of life. Epidemiological studies of balance disorders (BDs) are limited. Ide...
Longitudinal employment patterns and parental health: A cross-country look
Study aims Using a cross-country lens, we investigate the links between longitudinal work trajectories and health among parents with children under age 18....
The application of large language models in bariatric surgery: A scoping review
Background Exploratory applications of large language models within the specialized field of metabolic and bariatric surgery have begun to emerge. Nevertheless, existing research r...
Genomic insights into population structure and adaptive variation of Pimelodus yuma and Pimelodus grosskopfii in the Magdalena-Cauca Basin
The biodiversity of the Magdalena–Cauca Basin, Colombia’s main fluvial system, is under severe threat from anthropogenic activities, imperiling endemic fish species such as Pimelod...
ICU-acquired infections and mortality in community-acquired pneumonia–induced sepsis: Insights from a transcriptomic analysis
Objectives To evaluate the association between ICU-acquired infections and 28-day mortality in pneumonia-induced sepsis and to explore associated immune-related gene expression pat...
RNA metagenomic profiling of mosquito viromes associated with Vector-Borne diseases in Quebec, Canada
Mosquitoes harbor diverse viral communities, including both medically important arboviruses and insect-specific viruses, yet the viromes of mosquito populations in northern temperate regions remains p...
Association of Brachial-Ankle pulse pressure with coronary artery stenosis severity: A sex-specific cross-sectional study in Chinese adults
Objectives To investigate the association between brachial and ankle pulse pressure and the severity of coronary artery stenosis, as well as to explore sex-specific differences in...
Baseline endocrine factors influencing live birth outcomes in Chinese infertile women undergoing their first fresh IVF cycle: A multistate model-based cohort study
Conventional in vitro fertilization (IVF) outcome prediction is limited by static, single-endpoint analyses. We aimed to overcome this by using a multistate model to dissect the stage-specific and, cr...
Numerical and experimental assessment of hydrogen enrichment effects on ci engine characteristics fuelled with dual biodiesel blends: A comprehensive study
The growing need for energy around the world is putting pressure on established power sources like fossil fuels, making renewable energy solutions more concern. The high calorific value of hydrogen ha...
J-shaped relationship between stress hyperglycemia ratio and delirium risk in critically ill patients: A population-based study
Background The incidence of delirium in critically ill patients is strongly correlated with poor prognosis. The stress hyperglycemic ratio has emerged as a novel marker for assessi...
Mechanical response of high-porosity rocks under high triaxial confining pressure and experimental study of indentation tests
As oil and gas exploration and development continue to advance, ultra-deep and extra-deep formations have become the primary battleground for increasing global oil and gas reserves and production. The...
Establishment of a mouse intrauterine adhesion model via transvaginal mechanical injury guided by abdominal ultrasound
Objective To establish a clinically relevant mouse model of intrauterine adhesion (IUA) using a minimally invasive approach that combines real-time ultrasound guidance with control...
Facial soft tissue thicknesses of Azerbaijan adult population: CT study
The aim of this study was to create a facial soft tissue thicknesses database of Azerbaijan adult population and find relation between FSTT and sex, age, body mass index (BMI). The study investigates...
Feasibility study of prospective gated tomosynthesis using a wide-angle carbon nanotube enabled, stationary digital chest tomosynthesis scanner: In-vivo evaluation in a porcine subject
Background Tomosynthesis offers a valuable alternative to computed tomography (CT) in longitudinal studies for dose reduction and applications where CT is not an option. This study...
Characterizing malignant prognostic signatures in primary glioma based on single-cell and bulk transcriptome sequencing
Glioma, characterized by its highly invasive nature, presents significant challenges in prognosis and treatment resistance. The advent of single-cell RNA sequencing (scRNA-seq) has facilitated a more...
Urban compactness and Land Use Efficiency in Indochina Capitals: A multi-method spatial assessment (2017–2024)
This study assesses land use efficiency (LUE) and urban spatial structure in three Indochina capitals, Hanoi, Vientiane, and Phnom Penh, during the period 2017–2024. By integrating the SDG 11.3.1 indi...
Pre-analytical variables affecting breast cancer biomarker expression: A controlled single-specimen study of fixation duration, cold ischemia time, and fixative preparation in a low-resource setting
Background Optimal pre-analytical management of breast tissue specimens, particularly formalin fixation, is essential for accurate immunohistochemical (IHC) biomarker assessment in...
Association between the triglyceride-glycated hemoglobin index and diabetes risk among patients with Non-alcoholic fatty liver disease: A longitudinal cohort study
Background Emerging evidence suggests that the triglyceride-glycated hemoglobin index (TyH-i) may be a novel predictor of type 2 diabetes (T2D) risk. However, in patients diagnosed...
Why are some children under 24 months still undernourished in urban and peri-urban Vientiane? A mixed-methods study
Child undernutrition remains a significant public health challenge in many low and middle-income countries (LMICs), including Lao PDR, where high levels persist even in urban areas with generally avai...