PLoS ONE
Articles in this Issue
Which evolutionary game-theoretic model best captures NSCLC dynamics?
Understanding and predicting the eco-evolutionary dynamics of cancer requires identifying mathematical models that best capture tumor growth and treatment response. In this study, we fit a family of t...
Multi-omics and pan-cancer analysis revealed common molecular signatures to disclose multitargeted anticancer agents through network pharmacology approach
Cancer is characterized as a multifactorial disease due to their complex genetic and molecular mechanisms that often converge across tissue types. Shared oncogenic pathways can help us understand thes...
Gallstone disease classification using SLOA-optimized CatBoost classifier with explainable AI
Gallstones are small stones that form in the gallbladder. Around 80% of individuals with gallstones do not present any symptoms. Despite the high accuracy of image-based machine learning (ML) models i...
Comparative analysis of temperature effect on bandgap characteristics in 1D phononic crystals: Periodic versus quasiperiodic structures
Phononic crystal-based sensors have emerged as highly promising platforms for precise temperature monitoring due to their ability to manipulate acoustic wave propagation through engineered bandgaps. I...
A qualitative study of midlife women with type 2 diabetes in the UK: Exploring the impact of diabetes on their well-being
Background and aims Type 2 Diabetes mellitus (T2DM) substantially influences the overall well-being and quality of life of individuals with diabetes and is widely associated with p...
Clinical characteristics, management, and outcomes of pediatric non-infectious uveitis: A multicenter study in Saudi Arabia
Background Pediatric non-infectious uveitis is a challenging condition with significant risks for long-term ocular complications and visual impairment. Limited regional data on its...
Learning under uncertainty—Conservation of populations and persistence of dynamic resources through adaptive switching feedback controllers
In the context of conservation under uncertainty, the problem of designing and analysing adaptive switching feedback control schemes for systems of positive difference equations is considered. The aim...
Empowering future public health professionals: The impact of community-based education on students’ maternal and child health competencies
Preparing future public health professionals to address real-world maternal and child health (MCH) challenges requires educational approaches that extend beyond classroom instruction. In this context,...
DSE-YOLO11: Dynamic feature adaptation for key traffic element detection in complex road scenes
Accurate detection of key traffic elements in complex road scenes is critical for autonomous driving and intelligent transportation systems. However, existing lightweight detectors often suffer from m...
Retraction: SHP2 improved Late-onset fetal growth restriction via modulating ROS/BRD4/PI3K/YAP/PIGF signaling induced angiogenesis
Causes and trends of under-five mortality in the Gilgel Gibe Health and Demographic Surveillance System, 2005 to 2019, Southwest Ethiopia: Cohort study
Background Irrespective of intensive global efforts to reduce under-five mortality, it remains a significant public health concern. Understanding the causes and trends of under-fiv...
SVTRv2X: Enhanced scene text recognition via self-distilled mixture-of-experts
Scene Text Recognition (STR) is a fundamental component of intelligent perception systems and plays a crucial role in a wide range of real-world applications such as autonomous driving, document under...
Expression of Concern: Construction of a high-density genetic map and QTL analysis for yield, yield components and agronomic traits in chickpea (Cicer arietinum L.)
A sensitivity study on the measurement of urban polycentricity in chinese cities: Center definition, indicator selection, and their interaction effects
Research on urban polycentricity has long been hampered by fragmented case studies, inconsistent standardized criteria, and methodological misuse, complicating cross-study comparisons and limiting a n...
Temporal shift in task factor influence across the stretch reflex
Mechanical perturbations applied to the arm can elicit reflexive actions. These rapid corrective responses include the stretch reflex, which consists of different components: the short-latency reflex...
Security enhancement using scalable Blockchain-based Multi-Factor Authentication (BMFA)
As digital interactions continue to expand, securing online systems has become a fundamental priority. Multifactor authentication (MFA) plays a pivotal role in modern cybersecurity frameworks. Traditi...
Screening and comprehensive analysis of endoplasmic reticulum stress-related biomarkers in atherosclerosis
Atherosclerosis (AS) is a chronic inflammatory vascular disorder in which endoplasmic reticulum stress (ERS) plays a crucial regulatory role. However, the biological and translational relevance of ERS...
FGFR2 and favorable survival outcomes in resected poorly cohesive cell gastric cancer: Analysis from FGFR2 protein overexpression and genetic variation
Purpose Poorly cohesive cell gastric cancer has aggressive and heterogeneous characteristics. This study investigated the clinical significance of fibroblast growth factor receptor...
A dual-interface load transfer model for precast concrete-cored cemented soil piles considering progressive damage
Precast concrete-cored cemented soil piles (PCCS) are widely used to improve the bearing capacity of soft ground. However, existing design models usually assume perfect bonding between the concrete co...