PLoS ONE
Articles in this Issue
Identification of non-cardiomyocytes marker genes in patients with diabetes and cardiomyopathy through single-cell analysis
Background Diabetic cardiomyopathy (DCM) is a diabetes-related myocardial disorder causing fibrosis, hypertrophy, and progressive diastolic and systolic dysfunction. This study aim...
Social support and health related quality of life among older people in covid-19 pandemic: The mediating role of resilience
Background During emergencies and crises, comprehending the influence of various factors on the health-related quality of life (HRQoL) of older adults is crucial for enhancing it....
Prevalence and determinants of cigarette smoking and smoking frequency among people with tuberculosis in Lesotho: Evidence from a nationwide cross-sectional survey
Background Low- and middle-income countries face a significant dual burden of tuberculosis (TB) and cigarette smoking. Nevertheless, studies examining the prevalence and determinan...
Contemporary high resolution European forest structure assessed using tree-level National Forest Inventory data
This exploratory study presents an objective and consistent approach for assessing forest structure across multiple European countries, focusing on the distributions of tree species and tree diameter...
Expression of Concern: A study on the temperature profile of bifurcation tunnel fire under natural ventilation
From expert opinion to data driven selection of sports equipment: Boot selection in alpine ski racers
To compete successfully in alpine ski racing, not only physical, mental, and skiing technique preparation are important, but also wisely chosen and properly tuned skiing equipment. While equipment rel...
The role of premorbid cognitive performance in the neuropsychological assessment of people with HIV in South Africa
Background Cognitive assessment in people with HIV may be confounded by psychosocial factors, especially those linked to childhood circumstances, which are rarely measured in studi...
Correction: The increase in varus tilt of the joint line convergence angle under weight-bearing is correlated with medial meniscus extrusion in patients with knee osteoarthrosis
Spatiotemporal weather forecasting via multi-scale graph neural networks and latent diffusion models
Accurate weather prediction is crucial in agriculture, disaster prevention, and public safety. Challenge: Traditional numerical models have high computational costs and struggle with atmospheric nonli...
Atomistic insight into Al-Mg friction stir welding process via molecular dynamics simulation
Friction stir welding (FSW) has recently intrigued academics’ interest due to advances in high strength, low heat generation, tiny grain size, no melting, and the ability to produce dissimilar welding...
Treatment terminations during radiation therapy: A retrospective descriptive single-center analysis
Background Radiotherapy (RT) is a cornerstone of cancer management, substantially improving local tumor control and overall survival. However, a subset of patients fail to complete...
Mechanistic origin of high-cycle fatigue enhancement by grain refinement in AZ81 magnesium alloy for sports equipment
Lightweight, high-strength alloys are increasingly demanded in sports equipment. Magnesium (Mg) alloys are attractive due to their low density and high specific strength. This study systematically inv...
Interface-engineered nickel oxyhydroxide on carbon nanofibers for efficient urea oxidation and wastewater-to-energy conversion
Urea is a common nitrogenous pollutant in agricultural and industrial wastewaters, and its electrochemical oxidation in alkaline media enables simultaneous detoxification and energy recovery. Herein,...
Adapting, piloting, and evaluating a pediatric lead screening and risk-reduction intervention in Nairobi: A hybrid implementation-effectiveness trial protocol
Background Childhood lead exposure is prevalent worldwide including low- and middle-income countries (LMICs). Structured screening and prevention programs to address pediatric lead...
Markov reads Puškin, again: A statistical journey into the poetic world of Evgenij Onegin
This study applies symbolic time series analysis and Markov modeling to explore the phonological structure of Evgenij Onegin —as captured through a graphemic vo...
Mapping metabolic reprogramming in lung and breast cancer through integrative bioinformatics
Metabolic reprogramming is central to cancer biology, enabling tumor cells to sustain rapid proliferation, resist stress, and adapt to therapy. However, these alterations are highly heterogeneous acro...
Tool-stone selection in the African Middle stone age at Sibhudu cave
The raw materials people used for making stone tools may contain information about their territory, exchange routs or the selection criteria they employed during provisioning. In this study, we measur...
Effect of ciprofol–etomidate mixtures for deep sedation during gastrointestinal endoscopy: Protocol for a three-arm, double-blind randomized controlled trial
Introduction Deep sedation for gastrointestinal endoscopy can be achieved using either ciprofol or etomidate, both associated with distinct adverse events such as cardiopulmonary d...
Supporting entrepreneurial resilience: An experimental study protocol
Entrepreneurial activity is shaped by the structure and functioning of the entrepreneurial ecosystem, yet there is limited consensus on how entrepreneurial resilience is defined or measured. This stud...
Integrating deep learning, biological hierarchies, and high-resolution imagery to create a new identification tool for cryptic coral reef fishes
Life on Earth has evolved into a staggering diversity of species, most of which still remain undiscovered, unrecognized, or unmonitored. As our ocean’s richest biodiversity hotspot, coral reefs harbor...
AMGST: Adaptive multi-graph convolution and spatiotemporal attention network for traffic forecasting
Traffic forecasting is crucial for optimizing traffic management and control strategies. As a powerful approach for analyzing and mining graph-structured data, graph convolution has shown great potent...
Performance and safety of a fine-tuned small language model for pediatric emergency triage: A benchmark study
Pediatric emergency triage is a safety-critical task, and recent studies have explored whether artificial intelligence, including language models, can support triage decision-making; however, evidence...
Modelling cognitive outcomes in the UK Biobank: Education, noradrenaline and frontoparietal networks
Education is often used as a surrogate measure of so called cognitive reserve (CR) benefiting cognitive functioning in later years. In line with Robertson’s theory we tested here a hypothesis that edu...
Financial development and economic growth in Sub-Saharan Africa using system GMM analysis
The study on financial development and economic growth in Sub-Saharan Africa utilises System GMM analysis to investigate the relationship between financial development indicators and regional economic...
Exploring the genetic architecture underlying dietary fiber content in Colombian Andean blueberry (Vaccinium meridionale Swartz)
Dietary fiber composition is a major determinant of fruit nutritional quality, yet its genetic basis remains poorly characterized in wild Vaccinium species. Here, we combined extensive phenotyping wit...