PLoS ONE
Articles in this Issue
Perspective of Turkish society toward autistic individuals: Personal experiences, knowledge, and interaction comfort
Despite increasing awareness of autism spectrum disorder (ASD) and autistic individuals, factors shaping social interactions involving autistic individuals in the general population remain relatively...
Correction: Salidroside protects against high-altitude hypoxia-induced kidney injury via regulation of renal dopamine D1-like receptors
Synergic effect of dielectric barrier discharge plasma and hydrodynamic cavitation on decolorization of methylene blue
The growing demand for efficient and sustainable wastewater treatment technologies has driven the development of advanced oxidation processes (AOPs) that combine multiple physical and chemical mechani...
HIV-relevant policies in European countries: A comprehensive landscape of policies hindering or facilitating access to HIV prevention, testing, treatment, and care of key populations
Background In Europe, there are variations in epidemic patterns, trends, and progress toward achieving the UNAIDS target of ending the AIDS epidemic. Complex social, economic, cult...
EP300 promotes bladder cancer cell migration through SNAI2
EP300, a frequently mutated transcriptional coactivator in bladder cancer, has been demonstrated to positively correlate with malignancy in various cancers. Highly aggressive bladder cancers are often...
Prevalence and factors associated with microvascular and macrovascular diabetes complications in adult Ugandans: A systematic review and meta-analysis
Introduction The rising prevalence of diabetes in Uganda has led to a disproportionate increase in the burden of diabetes complications. We conducted a systematic review and meta-a...
Repetitive hypoxic preconditioning protects retinal ganglion cells against damage caused by exposure to blast
Visual system damage and dysfunction caused by exposure to a blast wave has been described in both clinical studies and in pre-clinical models. Within the retina, retinal ganglion cells (RGC) exhibit...
Leadership education to support person-centred health and social care: A scoping review of empirical literature
The purpose of this scoping review was to map evidence on leadership education to support person-centred care. Specifically, the review aimed to identify the key content of such education, the educati...
From defense to reconstruction: The hostility-meaning dual-path model of how observing others’ adversity influences distress disclosure
Objective This study explored the mechanism by which observing peers’ adverse experiences influences distress disclosure of negative information through two progressive studies....
Influence of person-organization fit on job satisfaction among pre-service preschool teachers of China: Mediation of teaching self-efficacy and perceived teacher competence
In China, a growing number of preschool education majors demonstrate reluctance to enter the profession upon graduation, posing a challenge to the sustainable development of the early childhood educat...
Species diversity and geographical distribution of ticks infesting domestic animals in Bagmati Province, Nepal
Background Ticks are important vectors for bacterial, viral, rickettsial, and protozoal diseases in different animals and humans, especially in tropical countries. Tick-borne patho...
Implementation of a clinical decision support tool to improve the adequate prescription of low-molecular-weight heparins in non-surgical patients
Background Non-surgical hospitalized patients have an increased risk of developing venous thromboembolism (VTE). This risk can be reduced by thromboprophylaxis with low-molecular-w...
Expression of melanoma differentiation–associated gene 5 in the epidermis and cutaneous deposition of complement C3 and immunoglobulins in patients with dermatomyositis
Objectives Dermatomyositis (DM) is an autoimmune disease characterized by interface dermatitis, but the immunopathological features underlying cutaneous inflammation remain incompl...
Integrating preliminary test and Stein-type techniques to improve estimation in the time-dependent Cox model
While shrinkage and preliminary test estimation have long been studied in linear and static Cox models, their theoretical integration within models featuring time-dependent covariates has remained unr...
Pathogen spectrum and epidemiology of respiratory tract infections in Quzhou, Eastern China, from November 2023 to July 2024: A post‑COVID‑19 surveillance study
Background After the relaxation of COVID‑19 containment measures, we investigated the pathogen spectrum and epidemiological characteristics of acute respiratory infections (ARIs) i...
Higher dietary polyphenol intake is associated with reduced pain sensitivity and migraine-related disability: A cross-sectional analysis
Introduction Migraine is a highly disabling neurological disorder characterized by recurrent headache attacks and altered pain processing. Emerging evidence suggests that dietary p...
Implicit processes do not contribute to learning to reach in small mirror reversed visuomotor environments
Learning to reach with a small visuomotor rotation (VR), where visual feedback regarding hand motion is rotated relative to one’s hand trajectory, has been shown to arise unconsciously (i.e., implicit...
How work hours affect well-being: A target trial emulation
Studies link longer work hours to multiple dimensions of well-being, but correlations do not show what would happen if hours changed. Target-trial emulation addresses this problem by specifying the ex...
Correction: The additive effect of IgE-mediated and pseudoallergic hypersensitivity in RBL-2H3 cells and guinea pigs
Sprint velocity and step frequency during repeated sprint ability testing are associated with high-intensity locomotor activity in elite female field hockey
Field hockey is an intermittent, high-intensity team sport in which global positioning system (GPS) monitoring and field-based fitness testing are widely used; however, the relationship between repeat...
Neuroblastoma cell growth and invasiveness is modulated by the activity of N-acetylglucosaminyltransferase-III
The presence of complex N-glycans with β1,6-N-acetylglucosamine (GlcNAc) on cells has long been associated with cancer. For this reason, the role of N-acetylglucosaminyltransferase-III (GnT-III,...
Exploring HIV prevention preferences among key populations in Uganda: A qualitative study
Long-acting injectable pre-exposure prophylaxis (PrEP) has recently been approved for use, and dissemination, but has yet to be released in Uganda. To ensure uptake of this injectable option, and othe...
Isolation of bioactive compounds from the petroleum ether soluble fraction of Eichhornia crassipes (Mart.) Solms flowers with dual evaluation: In silico studies of isolated molecules and in vitro/in vivo activities of the extract
Eichhornia crassipes (water hyacinth), an invasive aquatic plant, has attracted interest as a potential source of pharmacologically active natural products despite its ecological i...
Advanced glycation end product accumulation was associated with renal function impairment in males in large health examination population
The accumulation of advanced glycation end products (AGEs) is a risk factor for renal dysfunction. However, no investigation has been conducted on the association between AGEs and renal function in he...
Reinforcement learning for policymaking in epidemic control: A scoping review
Background Managing an epidemic demands policies that respond at the pace of the outbreak. Conventional rule‑based interventions struggle to keep up, prompting interest in reinforc...